English
Related papers

Related papers: Optogenetic control of cell signaling pathway thro…

200 papers

Focusing light through turbid media presents a highly fascinating challenge in modern biophotonics. The unique capability of optoacoustics for high resolution imaging of light absorption contrast in deep tissues can provide a natural and…

Optics · Physics 2015-02-03 X. Luís Deán-Ben , Héctor Estrada , Daniel Razansky

Wavefront shaping is a technique to study and control light transport inside scattering media. Wavefront shaping is considered to be applicable to any complex material, yet in most previous studies, the only sample geometries that are…

Shaping light deep inside complex media, such as biological tissue, is critical to many research fields. Although the coherent control of scattered light via wavefront shaping has made significant advances in addressing this challenge,…

Optics · Physics 2023-09-21 YoonSeok Baek , Hilton B. de Aguiar , Sylvain Gigan

Focusing light into opaque random or scattering media such as biological tissue is a much sought-after goal for biomedical applications such as photodynamic therapy, optical manipulation, and photostimulation. However, focusing with…

Optics · Physics 2014-03-10 Jian Wei Tay , Puxiang Lai , Yuta Suzuki , Lihong V. Wang

Chemo-mechanical waves on active deformable surfaces are a key component for many vital cellular functions. In particular, these waves play a major role in force generation and long-range signal transmission in cells that dynamically change…

Wavefront shaping techniques allow waves to be focused on a diffraction-limited target deep inside disordered media. To identify the target position, a guidestar is required that typically emits a frequency-shifted signal. Here we present a…

Applied Physics · Physics 2025-05-13 Antton Goïcoechea , Jakob Hüpfl , Stefan Rotter , François Sarrazin , Matthieu Davy

Multiple light scattering in tissue limits the penetration of optical coherence tomography (OCT) imaging. Here, we present in-vivo OCT imaging of a live mouse using wavefront shaping to enhance the penetration depth. A digital micro-mirror…

Scattering has usually be considered as detrimental for optical focusing or imaging. Recently, more and more research has shown that strongly scattering materials can be utilized to focus coherent light by controlling or shaping the…

Optics · Physics 2017-05-24 Yanqi Qiao , Xianfeng Chen , Yajun Peng , Yuanlin Zheng

After multiple scattering of quadrature-squeezed lights in a disordered medium, the quadrature amplitudes of the scattered modes present an excess noise above the shot-noise level [Opt. Expr. 14, 6919 (2006)]. A natural question is raised…

Quantum Physics · Physics 2020-01-08 Dong Li , Yao Yao

We report the first experimental demonstration of combined spatial and temporal control of light trajectories through opaque media. This control is achieved by solely manipulating spatial degrees of freedom of the incident wavefront. As an…

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Scattering prevents light from being focused in turbid media. The effect of scattering can be negated through wavefront shaping techniques when a localized form of feedback is available. Even in the absence of such a localized reporter,…

Optics · Physics 2019-05-01 Gerwin Osnabrugge , Lyubov V. Amitonova , Ivo M. Vellekoop

We demonstrate the control of entanglement of a single photon between several spatial modes propagating through a strongly scattering medium. Measurement of the scattering matrix allows the wavefront of the photon to be shaped to compensate…

A perfectly collimated beam can be spread out by multiple scattering, creating a speckle pattern and increasing the etendue of the system. Standard optical systems conserve etendue, and thus are unable to reverse the process by transforming…

Optics · Physics 2021-07-23 Alba M. Paniagua-Diaz , William L. Barnes , Jacopo Bertolotti

A random medium can serve as a controllable arbitrary spectral filter with spectral resolution determined by the inverse of the interaction time of the light in the medium. We use wavefront shaping to implement an arbitrary spectral…

Optics · Physics 2015-06-05 Eran Small , Ori Katz , Yefeng Guan , Yaron Silberberg

We present and experimentally verify a matrix approach for determining how to optimally sculpt an input wavefront both in space and time for any desired wave-control functionality, irrespective of the complexity of the wave scattering. We…

Applied Physics · Physics 2023-08-08 Clément Ferise , Philipp del Hougne , Matthieu Davy

The increasing complexity of neural networks and the energy consumption associated with training and inference create a need for alternative neuromorphic approaches, e.g. using optics. Current proposals and implementations rely on physical…

Optics · Physics 2023-08-31 Clara C. Wanjura , Florian Marquardt

Over the past decade, techniques enabling bidirectional modulation of neuronal activity with single cell precision have rapidly advanced in the form of two-photon optogenetic stimulation. Unlike conventional electrophysiological approaches…

Neurons and Cognition · Quantitative Biology 2025-09-01 Riichiro Hira , Yoshikazu Isomura

Optogenetics has emerged as an exciting tool for manipulating neural activity, which in turn, can modulate behavior in live organisms. However, detecting the response to the optical stimulation requires electrophysiology with physical…

Light propagation in materials with microscopic inhomogeneities is affected by scattering. In scattering materials, such as powders, disordered metamaterials or biological tissue, multiple scattering on sub-wavelength particles makes light…

Disordered Systems and Neural Networks · Physics 2009-11-13 I. M. Vellekoop , A. P. Mosk