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Recent advances in digital pathology have led to the need for Histopathology Image Retrieval (HIR) systems that search through databases of biopsy images to find similar cases to a given query image. These HIR systems allow pathologists to…
Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…
Multiplex immunofluorescence (mIF) enables simultaneous single-cell quantification of multiple biomarkers within intact tissue architecture, yet its high reagent cost, multi-round staining protocols, and need for specialized imaging…
Superpixel segmentation has become an important research problem in image processing. In this paper, we propose an Iterative Spanning Forest (ISF) framework, based on sequences of Image Foresting Transforms, where one can choose i) a seed…
Within the domain of texture classification, a lot of effort has been spent on local descriptors, leading to many powerful algorithms. However, preprocessing techniques have received much less attention despite their important potential for…
Fine-grained image recognition is very challenging due to the difficulty of capturing both semantic global features and discriminative local features. Meanwhile, these two features are not easy to be integrated, which are even conflicting…
We propose a general framework for a collaborative machine learning system to assist bioscience researchers with the task of labeling specific cell identities from microscopic still or video imaging. The distinguishing features of this…
As modern complex neural networks keep breaking records and solving harder problems, their predictions also become less and less intelligible. The current lack of interpretability often undermines the deployment of accurate machine learning…
We present a novel methodology for integrating high resolution longitudinal data with the dynamic prediction capabilities of survival models. The aim is two-fold: to improve the predictive power while maintaining interpretability of the…
Cellular composition prediction, i.e., predicting the presence and counts of different types of cells in the tumor microenvironment from a digitized image of a Hematoxylin and Eosin (H&E) stained tissue section can be used for various tasks…
Fluorescence labeling is the standard approach to reveal cellular structures and other subcellular constituents for microscopy images. However, this invasive procedure may perturb or even kill the cells and the procedure itself is highly…
Breast cancer (BC) is the most common cancer among women world-wide, approximately 20-25% of BCs are HER-2 positive. Analysis of HER-2 is fundamental to defining the appropriate therapy for patients with breast cancer. Inter-pathologist…
Inspired by the combination of feedforward and iterative computations in the virtual cortex, and taking advantage of the ability of denoising autoencoders to estimate the score of a joint distribution, we propose a novel approach to…
Multi-exposure image fusion (MEF) has emerged as a prominent solution to address the limitations of digital imaging in representing varied exposure levels. Despite its advancements, the field grapples with challenges, notably the reliance…
Multilayer Extreme Learning Machine (ML-ELM) and its variants have proven to be an effective technique for the classification of different natural signals such as audio, video, acoustic and images. In this paper, a Hybrid Multilayer Extreme…
State-of-the-art techniques for 6D object pose recovery depend on occlusion-free point clouds to accurately register objects in 3D space. To deal with this shortcoming, we introduce a novel architecture called Iterative Hough Forest with…
Cell segmentation for multi-modal microscopy images remains a challenge due to the complex textures, patterns, and cell shapes in these images. To tackle the problem, we first develop an automatic cell classification pipeline to label the…
With such a massive growth in the number of images stored, efficient search in a database has become a crucial endeavor managed by image retrieval systems. Image Retrieval with Relevance Feedback (IRRF) involves iterative human interaction…
We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…
Incoherent Fourier ptychography (IFP) is a newly developed super-resolution method, where accurate knowledge of translation positions is essential for image reconstruction.To release this limitation, we propose a preprocessing algorithm…