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Ultra-thin multimode optical fiber imaging promises next-generation medical endoscopes reaching high image resolution for deep tissues. However, current technology suffers from severe optical distortion, as the fiber's calibration is…

Optics · Physics 2023-10-04 Yijie Zheng , George S. D. Gordon

In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Phase Contrast Imaging (PCI), Dark-Field (DF) and Directional Dark-Field (DDF) imaging are recent X-ray imaging modalities that have demonstrated their interest by providing access to information and contrasts different from those provided…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Clara Magnin , Laurene Quenot , Sylvain Bohic , Dan Mihai Cenda , Manuel Fernández Martínez , Blandine Lantz , Bertrand Faure , Emmanuel Brun

The back-focal plane (BFP) of a high-numerical aperture objective contains the fluoro-phore radiation pattern, which encodes information about the axial fluorophore position, molecular orientation and the local refractive index of the…

Over the last decade, the light microscope has become increasingly useful as a quantitative tool for studying colloidal systems. The ability to obtain particle coordinates in bulk samples from micrographs is particularly appealing. In this…

Soft Condensed Matter · Physics 2007-09-27 Matthew C. Jenkins , Stefan U. Egelhaaf

Dispersion-based photonics-assisted microwave measurement systems provide immense potential for real-time analysis of wideband and dynamic signals. However, they face two critical challenges: a difficulty in achieving high frequency…

Optics · Physics 2026-02-13 Chi Jiang , Taixia Shi , Hang Yang , Lei Gao , Xianxin Zhang , Yiqing Liu , Yang Chen

A general-purpose all-fiber spectrometer is demonstrated to overcome the trade-off between spectral resolution and bandwidth. By integrating a wavelength division multiplexer with five multimode optical fibers, we have achieved 100 nm…

Instrumentation and Detectors · Physics 2016-08-26 Seng Fatt Liew , Brandon Redding , Michael A. Choma , Hemant D. Tagare , Hui Cao

In clinical practice, tri-modal medical image fusion, compared to the existing dual-modal technique, can provide a more comprehensive view of the lesions, aiding physicians in evaluating the disease's shape, location, and biological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yushen Xu , Xiaosong Li , Yuchan Jie , Haishu Tan

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

Optics · Physics 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

Optical imaging plays a critical role in advancing our understanding of three dimensional dynamics of biological systems. Coherent imaging (CI) methods exploit spatial phase information, encoded through propagation of coherent signal light…

Optics · Physics 2015-07-24 Jeffrey J. Field , David G. Winters , Randy A. Bartels

Minimally invasive imaging with fiber optic endoscopes is crucial for in vivo visualization of tissue morphology, particularly because visualizing structural changes in tissue can support applications such as the early diagnosis of tumors.…

We present a novel design that exploits the focusing properties of scattering media to increase the resolution and the working distance of multimode fiber based imaging devices. Placing a highly scattering medium in front of the distal tip…

Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system performance beyond the limit defined by its optical elements. The FPM technique applies a novel…

Optics · Physics 2014-05-02 Xiaoze Ou , Roarke Horstmeyer , Changhuei Yang , Guoan Zheng

We present a superpixel method for full spatial phase and amplitude control of a light beam using a digital micromirror device (DMD) combined with a spatial filter. We combine square regions of nearby micromirrors into superpixels by low…

Optics · Physics 2015-06-19 Sebastianus A. Goorden , Jacopo Bertolotti , Allard P. Mosk

Image Phase Alignment Super-Sampling (ImPASS) is a computational imaging algorithm for converting a sequence of displaced low-resolution images into a single high-resolution image. The method consists of a unique combination of Phase…

Optics · Physics 2025-09-01 James N. Caron

Multimode optical fibers represent the ideal platform for transferring multidimensional light states. However, dispersion degrades the correlations between the light's degrees of freedom, thus limiting the effective transport of ultrashort…

Light-field imaging is an emerging paradigm in biomedical optics, offering the unique ability to capture volumetric information in a single snapshot by encoding both the spatial and angular components of light. Unlike conventional…

Optics · Physics 2025-09-30 Ruixuan Zhao , Xuanwen Hua , Woongjae Baek , Zhaoqiang Wang , Shu Jia , Liang Gao

Holography has always held special appeal, for it is able to record and display spatial information in three dimensions. Here, we show how to augment the capabilities of digital holography by using a large number of narrow laser lines at…

X-ray microtomography is a powerful non-destructive technique allowing 3D virtual histology of resected human tissue. The achievable imaging field-of-view, is however limited by the fixed number of detector elements, enforcing the…

Additive manufacturing, also known as 3D printing, is an advanced manufacturing technique that allows the fabrication of arbitrary macroscopic and microscopic objects. All 3D printing systems require large optical elements or nozzles in…