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The adoption of deep learning techniques in genomics has been hindered by the difficulty of mechanistically interpreting the models that these techniques produce. In recent years, a variety of post-hoc attribution methods have been proposed…

Molecular Networks · Quantitative Biology 2020-02-11 Ammar Tareen , Justin B. Kinney

The vast majority of natural sensory data is temporally redundant. Video frames or audio samples which are sampled at nearby points in time tend to have similar values. Typically, deep learning algorithms take no advantage of this…

Neural and Evolutionary Computing · Computer Science 2017-06-14 Peter O'Connor , Efstratios Gavves , Max Welling

We formulate the search for phenomenological models of synaptic plasticity as an optimization problem. We employ Cartesian genetic programming to evolve biologically plausible human-interpretable plasticity rules that allow a given network…

Neural and Evolutionary Computing · Computer Science 2021-02-09 Henrik D. Mettler , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici , Jakob Jordan

The creation of machine learning algorithms for intelligent agents capable of continuous, lifelong learning is a critical objective for algorithms being deployed on real-life systems in dynamic environments. Here we present an algorithm…

Machine Learning · Computer Science 2020-01-28 Andrew Brna , Ryan Brown , Patrick Connolly , Stephen Simons , Renee Shimizu , Mario Aguilar-Simon

Recurrent spiking neural networks (RSNN) in the human brain learn to perform a wide range of perceptual, cognitive and motor tasks very efficiently in terms of energy consumption and requires very few examples. This motivates the search for…

Neurons and Cognition · Quantitative Biology 2021-03-22 Paolo Muratore , Cristiano Capone , Pier Stanislao Paolucci

Deep learning continues to play as a powerful state-of-art technique that has achieved extraordinary accuracy levels in various domains of regression and classification tasks, including images, video, signal, and natural language data. The…

Neural and Evolutionary Computing · Computer Science 2022-06-03 Anna Zou , Zhiyuan Li

This paper introduces a new biologically-inspired training method named Continual Learning through Adjustment Suppression and Sparsity Promotion (CLASSP). CLASSP is based on two main principles observed in neuroscience, particularly in the…

Neural and Evolutionary Computing · Computer Science 2024-06-11 Oswaldo Ludwig

Uncertainty computation in deep learning is essential to design robust and reliable systems. Variational inference (VI) is a promising approach for such computation, but requires more effort to implement and execute compared to…

Machine Learning · Statistics 2018-08-03 Mohammad Emtiyaz Khan , Didrik Nielsen , Voot Tangkaratt , Wu Lin , Yarin Gal , Akash Srivastava

Backpropagation (BP) is the standard algorithm for training the deep neural networks that power modern artificial intelligence including large language models. However, BP is energy inefficient and unlikely to be implemented by the brain.…

Machine Learning · Computer Science 2025-10-30 Francesco Innocenti

Brain-inspired learning models attempt to mimic the cortical architecture and computations performed in the neurons and synapses constituting the human brain to achieve its efficiency in cognitive tasks. In this work, we present…

Neural and Evolutionary Computing · Computer Science 2017-03-21 Priyadarshini Panda , Gopalakrishnan Srinivasan , Kaushik Roy

Brain-inspired machine intelligence research seeks to develop computational models that emulate the information processing and adaptability that distinguishes biological systems of neurons. This has led to the development of spiking neural…

Neural and Evolutionary Computing · Computer Science 2024-10-28 Alexander Ororbia

A growing body of work underlines striking similarities between biological neural networks and recurrent, binary neural networks. A relatively smaller body of work, however, discusses similarities between learning dynamics employed in deep…

Neural and Evolutionary Computing · Computer Science 2020-05-22 Jacques Kaiser , Hesham Mostafa , Emre Neftci

Modern deep neural networks are well known to be brittle in the face of unknown data instances and recognition of the latter remains a challenge. Although it is inevitable for continual-learning systems to encounter such unseen concepts,…

Machine Learning · Computer Science 2022-04-04 Martin Mundt , Iuliia Pliushch , Sagnik Majumder , Yongwon Hong , Visvanathan Ramesh

The key idea behind the unsupervised learning of disentangled representations is that real-world data is generated by a few explanatory factors of variation which can be recovered by unsupervised learning algorithms. In this paper, we…

Machine Learning · Computer Science 2019-06-19 Francesco Locatello , Stefan Bauer , Mario Lucic , Gunnar Rätsch , Sylvain Gelly , Bernhard Schölkopf , Olivier Bachem

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

Deep learning is computationally intensive, with significant efforts focused on reducing arithmetic complexity, particularly regarding energy consumption dominated by data movement. While existing literature emphasizes inference, training…

Machine Learning · Statistics 2025-06-09 Van Minh Nguyen , Cristian Ocampo , Aymen Askri , Louis Leconte , Ba-Hien Tran

Compositionality is a basic structural feature of both biological and artificial neural networks. Learning compositional functions via gradient descent incurs well known problems like vanishing and exploding gradients, making careful…

Neural and Evolutionary Computing · Computer Science 2021-01-11 Jeremy Bernstein , Jiawei Zhao , Markus Meister , Ming-Yu Liu , Anima Anandkumar , Yisong Yue

Deep Reinforcement Learning has demonstrated the potential of neural networks tuned with gradient descent for solving complex tasks in well-delimited environments. However, these neural systems are slow learners producing specialized agents…

Machine Learning · Computer Science 2022-10-13 Mathieu Chalvidal , Thomas Serre , Rufin VanRullen

By and large, Backpropagation (BP) is regarded as one of the most important neural computation algorithms at the basis of the progress in machine learning, including the recent advances in deep learning. However, its computational structure…

Artificial Intelligence · Computer Science 2018-08-22 Alessandro Betti , Marco Gori , Giuseppe Marra

Finding an interpretable non-redundant representation of real-world data is one of the key problems in Machine Learning. Biological neural networks are known to solve this problem quite well in unsupervised manner, yet unsupervised…

Machine Learning · Computer Science 2020-10-13 Denis Kuzminykh , Laida Kushnareva , Timofey Grigoryev , Alexander Zatolokin
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