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In order to interpret recent experimental studies of the dependence of conductance of ds-DNA as the DNA is pulled from the 3'end1-3'end2 ends, which find a sharp conductance jump for a very short (4.5 %) stretching length, we carried out…

Soft Condensed Matter · Physics 2016-08-26 Saientan Bag , Santosh Mogurampelly , William A Goddard , Prabal K Maiti

We simulate the electronic and transport properties of metal/two-dimensional material/metal vertical heterostructures, with a focus on graphene, hexagonal boron nitride and two phases of molybdenum diselenide. Using density functional…

Mesoscale and Nanoscale Physics · Physics 2025-02-06 Gaëlle Bigeard , Zineb Kerrami , François Triozon , Alessandro Cresti

The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting…

Biomolecules · Quantitative Biology 2007-05-23 Richard A. Neher , Ulrich Gerland

At present, there have been suggested two types of physical mechanism that may facilitate preferential pairing between DNA molecules, with identical or similar base pair texts, without separation of base pairs. One solely relies on base…

Biological Physics · Physics 2017-11-06 Dominic. J. , Lee

Helical molecules have been identified as potential candidates for investigating electronic transport, spin filtering, or even piezoelectricity. However, the description of the transport mechanism is not straightforward in single molecular…

Dielectrophoretic trapping of six different DNA fragments, sizes varying from the 27 to 8416 bp, has been studied using confocal microscopy. The effect of the DNA length and the size of the constriction between nanoscale fingertip…

The Histone-like Nucleoid Structuring protein (H-NS) is a nucleoid-associated protein, which is involved in both gene regulation and DNA compaction. H-NS can bind to DNA in two different ways: in trans, by binding to two separate DNA…

Biological Physics · Physics 2013-04-04 Marc Joyeux , Jocelyne Vreede

A model of self-avoiding walk with suitable constraints on self-attraction is developed to describe the conformational behaviour of a single stranded short DNA molecule that form hairpin structure. Using exact enumeration method we…

Soft Condensed Matter · Physics 2007-05-23 Debaprasad Giri , Sanjay Kumar , Yashwant Singh

Optical experiments on calf thymus DNA films subjected to different buffer environments are reported. The optical conductivity is that of a disordered or lightly doped semiconductor with a well-defined band-gap for charge excitations and…

Disordered Systems and Neural Networks · Physics 2007-05-23 E. Helgren , G. Gruner , A. Omerzu , D. Mihailovic , R. Podgornik , H. Grimm

Within a simple elastic theory, we study the elongation versus force characteristics of a supercoiled DNA molecule at thermal equilibrium in the regime of small supercoiling. The partition function is mapped to the path integral…

Soft Condensed Matter · Physics 2016-08-31 C. Bouchiat , M. Mezard

In eukaryotic genomes, nucleosomes function to compact DNA and to regulate access to it both by simple physical occlusion and by providing the substrate for numerous covalent epigenetic tags. While nucleosome positions in vitro are…

We present an elastic model of B-form DNA as a stack of thin, rigid plates or base pairs that are not permitted to deform. The symmetry of DNA and the constraint of plate rigidity limit the number of bulk elastic constants contributing to a…

Soft Condensed Matter · Physics 2009-10-30 C. S. O'Hern , Randall D. Kamien , T. C. Lubensky , Philip Nelson

DNA inside the cellular environment works under a confined space. An intense research of the transcription and replication of DNA in the confined state is structurally significant to command the self assembly of DNA in a chamber or channel.…

Soft Condensed Matter · Physics 2020-01-14 Arghya Maity , Navin Singh

We present in this paper an original approach to compute the electrophoretic mobility of rigid nucleo-protein complexes like nucleosomes. This model allows to address theoretically the influence of complex position along DNA, as well as…

Biological Physics · Physics 2016-08-14 Martin Castelnovo , Sébastian Grauwin

We perform a single molecule force spectroscopy study to characterize the role of the size (molecular weight) and concentration of depleting agents on DNA condensation and on the stabilization of the double-helix structure, showing that…

Soft Condensed Matter · Physics 2023-10-26 R. M. de Oliveira , M. S. Rocha

Cooperativity plays an important role in the action of proteins bound to DNA. A simple, mechanical mechanism for cooperativity, in the form of a tension-mediated interaction between proteins bound to DNA at two different locations is…

Soft Condensed Matter · Physics 2009-10-31 Joseph Rudnick , Robijn Bruinsma

Debates about conductivity of DNAs have been recently renewed due to contradictory results of direct measurements by use of electrical contacts to molecules. In several works it was discovered that double-stranded (ds)DNAs are conductors:…

Condensed Matter · Physics 2007-05-23 A. Yu. Kasumov , D. V. Klinov

The structure of DNA in the nucleosome core particle is studied using an elastic model that incorporates anisotropy in the bending energetics and twist-bend coupling. Using the experimentally determined structure of nucleosomal DNA [T.J.…

Biomolecules · Quantitative Biology 2009-11-13 Farshid Mohammad-Rafiee , Ramin Golestanian

We here present a variable-range hopping model to describe the chirality-induced spin selectivity along the DNA double helix. In this model, DNA is considered as a one-dimensional disordered system, where electrons are transported by chiral…

Mesoscale and Nanoscale Physics · Physics 2024-05-01 Ryotaro Sano , Takeo Kato

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

Soft Condensed Matter · Physics 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can