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Purpose: The goal of this work was to develop a deep network for whole-head segmentation including clinical MRIs with abnormal anatomy, and compile the first public benchmark dataset for this purpose. We collected 98 MRIs with volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-09-04 Andrew M Birnbaum , Adam Buchwald , Peter Turkeltaub , Adam Jacks , George Carra , Shreya Kannana , Yu Huang , Abhisheck Datta , Lucas C Parra , Lukas A Hirsch

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…

Accurate brain tissue segmentation in Magnetic Resonance Imaging (MRI) has attracted the attention of medical doctors and researchers since variations in tissue volume help in diagnosing and monitoring neurological diseases. Several…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Mariano Cabezas , Sergi Valverde , Arnau Oliver , Xavier Lladó

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

A major challenge in brain tumor treatment planning and quantitative evaluation is determination of the tumor extent. The noninvasive magnetic resonance imaging (MRI) technique has emerged as a front-line diagnostic tool for brain tumors…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Hao Dong , Guang Yang , Fangde Liu , Yuanhan Mo , Yike Guo

Recently deep learning has been playing a major role in the field of computer vision. One of its applications is the reduction of human judgment in the diagnosis of diseases. Especially, brain tumor diagnosis requires high accuracy, where…

Computer Vision and Pattern Recognition · Computer Science 2018-09-24 Zahra Sobhaninia , Safiyeh Rezaei , Alireza Noroozi , Mehdi Ahmadi , Hamidreza Zarrabi , Nader Karimi , Ali Emami , Shadrokh Samavi

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

Automated segmentation of anatomical sub-regions with high precision has become a necessity to enable the quantification and characterization of cells/ tissues in histology images. Currently, a machine learning model to analyze…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Hosein Barzekar , Hai Ngu , Han Hui Lin , Mohsen Hejrati , Steven Ray Valdespino , Sarah Chu , Baris Bingol , Somaye Hashemifar , Soumitra Ghosh

We describe a fully-automatic 3D-segmentation technique for brain MR images. Using Markov random fields the segmentation algorithm captures three important MR features, i.e. non-parametric distributions of tissue intensities, neighborhood…

Computer Vision and Pattern Recognition · Computer Science 2009-03-20 Karsten Held , Elena Rota Kops , Bernd J. Krause , William M. Wells , Ron Kikinis , Hans-Wilhelm Mueller-Gaertner

Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Zhihua Liu , Lei Tong , Zheheng Jiang , Long Chen , Feixiang Zhou , Qianni Zhang , Xiangrong Zhang , Yaochu Jin , Huiyu Zhou

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

The task of medical image segmentation commonly involves an image reconstruction step to convert acquired raw data to images before any analysis. However, noises, artifacts and loss of information due to the reconstruction process are…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Qiaoying Huang , Xiao Chen , Dimitris Metaxas , Mariappan S. Nadar

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Image segmentation some of the challenging issues on brain magnetic resonance image tumor segmentation caused by the weak correlation between magnetic resonance imaging intensity and anatomical meaning.With the objective of utilizing more…

Computer Vision and Pattern Recognition · Computer Science 2014-03-25 Narkhede Sachin G. , Vaishali Khairnar , Sujata Kadu

Automated segmentation of brain tumors from 3D magnetic resonance images (MRIs) is necessary for the diagnosis, monitoring, and treatment planning of the disease. Manual delineation practices require anatomical knowledge, are expensive,…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Andriy Myronenko

Accurate and reliable brain tumor segmentation is a critical component in cancer diagnosis, treatment planning, and treatment outcome evaluation. Build upon successful deep learning techniques, a novel brain tumor segmentation method is…

Computer Vision and Pattern Recognition · Computer Science 2017-11-13 Xiaomei Zhao , Yihong Wu , Guidong Song , Zhenye Li , Yazhuo Zhang , Yong Fan

Segmentation of brain structures from magnetic resonance (MR) scans plays an important role in the quantification of brain morphology. Since 3D deep learning models suffer from high computational cost, 2D deep learning methods are favored…

Image and Video Processing · Electrical Eng. & Systems 2021-03-09 Yuemeng Li , Hongming Li , Yong Fan