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The problem of achieving consensus in a network of connected systems arises in many science and engineering applications. In contrast to previous works, we focus on the system reactivity, i.e., the initial amplification of the norm of the…

Systems and Control · Electrical Eng. & Systems 2023-06-21 Amirhossein Nazerian , David Phillips , Hernan A. Makse , Francesco Sorrentino

It is well known that, for mass-action systems, complex-balanced equilibria are asymptotically stable. For generalized mass-action systems, even if there exists a unique complex-balanced equilibrium (in every stoichiometric class and for…

Dynamical Systems · Mathematics 2022-09-14 Balazs Boros , Stefan Müller , Georg Regensburger

We introduce KiNetX, a fully automated meta-algorithm for the kinetic analysis of complex chemical reaction networks derived from semi-accurate but efficient electronic structure calculations. It is designed to (i) accelerate the automated…

Chemical Physics · Physics 2019-01-11 Jonny Proppe , Markus Reiher

Despite their topological complexity almost all functional properties of metabolic networks can be derived from steady-state dynamics. Indeed, many theoretical investigations (like flux-balance analysis) rely on extracting function from…

Molecular Networks · Quantitative Biology 2009-11-13 Carsten Marr , Mark Mueller-Linow , Marc-Thorsten Huett

A major challenge in network science is to determine parameters governing complex network dynamics from experimental observations and theoretical models. In complex chemical reaction networks, for example, such as those describing processes…

Disordered Systems and Neural Networks · Physics 2021-06-02 Zachary G. Nicolaou , Adilson E. Motter

Certain chemical reaction networks (CRNs) when modeled as a deterministic dynamical system taken with mass-action kinetics have the property of reaction network detailed balance (RNDB) which is achieved by imposing network-related…

Probability · Mathematics 2014-12-30 Badal Joshi

We show that discrete distributions on the $d$-dimensional non-negative integer lattice can be approximated arbitrarily well via the marginals of stationary distributions for various classes of stochastic chemical reaction networks. We…

Computational Complexity · Computer Science 2019-10-01 Daniele Cappelletti , Andrés Ortiz-Muñoz , David Anderson , Erik Winfree

We lay the foundation of a circuit theory for chemical reaction networks. Chemical reactions are grouped into chemical modules solely characterized by their current-concentration characteristic, as electrical devices by their…

Molecular Networks · Quantitative Biology 2023-07-27 Francesco Avanzini , Nahuel Freitas , Massimiliano Esposito

Evolution produces complex and structured networks of interacting components in chemical, biological, and social systems. We describe a simple mathematical model for the evolution of an idealized chemical system to study how a network of…

Adaptation and Self-Organizing Systems · Physics 2014-03-05 Sanjay Jain , Sandeep Krishna

We propose a new approach to study the long time dynamics of the wave kinetic equation in the statistical description of acoustic turbulence. The approach is based on rewriting the discrete version of the wave kinetic equation in the form…

Mathematical Physics · Physics 2021-07-09 Minh-Binh Tran , Gheorghe Craciun , Leslie M. Smith , Stanislav Boldyrev

In network theory, a question of prime importance is how to assess network vulnerability in a fast and reliable manner. With this issue in mind, we investigate the response to parameter changes of coupled dynamical systems on complex…

Adaptation and Self-Organizing Systems · Physics 2018-02-27 Melvyn Tyloo , Tommaso Coletta , Philippe Jacquod

Empirical studies of graphs have contributed enormously to our understanding of complex systems. Known today as network science, what was originally a theoretical study of graphs has grown into a more scientific exploration of communities…

Quantitative Methods · Quantitative Biology 2020-01-01 Ryan E. Langendorf , Debra S. Goldberg

A class of systems is considered, where immobile species associated to distinct patches, the nodes of a network, interact both locally and at a long-range, as specified by an (interaction) adjacency matrix. Non local interactions are…

Pattern Formation and Solitons · Physics 2020-06-30 Giulia Cencetti , Federico Battiston , Timoteo Carletti , Duccio Fanelli

A detailed understanding of biochemical networks at the molecular level is essential for studying complex cellular processes. In this paper, we provide a comprehensive description of biochemical networks by considering individual atoms and…

Molecular Networks · Quantitative Biology 2025-04-08 Hadjar Rahou , Hulda S. Haraldsdottir , Filippo Martinelli , Ines Thiele , Ronan M. T. Fleming

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

A faithful description of the state of a complex dynamical network would require, in principle, the measurement of all its $d$ variables, an infeasible task for systems with practical limited access and composed of many nodes with high…

Chaotic Dynamics · Physics 2019-05-06 Christophe Letellier , Irene Sendiña-Nadal , Luis A. Aguirre

Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to…

Molecular Networks · Quantitative Biology 2012-02-21 Ronan M. T. Fleming , Ines Thiele

The long time behavior of a model for a first order, weakly reversible chemical reaction network is considered, where the movement of the reacting species is described by kinetic transport. The reactions are triggered by collisions with a…

Analysis of PDEs · Mathematics 2020-02-18 Gianluca Favre , Christian Schmeiser

It is common for people to access multiple social networks, for example, using phone, email, and social media. Together, the multi-layer social interactions form a "integrated social network." How can we extend well developed knowledge…

Social and Information Networks · Computer Science 2016-09-07 Kristina Lerman , Shang-Hua Teng , Xiaoran Yan

The behavior of some stochastic chemical reaction networks is largely unaffected by slight inaccuracies in reaction rates. We formalize the robustness of state probabilities to reaction rate deviations, and describe a formal connection…

Computational Complexity · Computer Science 2009-01-28 David Soloveichik