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Bioinformatics research is characterized by voluminous and incremental datasets and complex data analytics methods. The machine learning methods used in bioinformatics are iterative and parallel. These methods can be scaled to handle big…

Computational Engineering, Finance, and Science · Computer Science 2015-06-17 Hirak Kashyap , Hasin Afzal Ahmed , Nazrul Hoque , Swarup Roy , Dhruba Kumar Bhattacharyya

Solid-state drives (SSDs) have revolutionized data storage with their high performance, energy efficiency, and reliability. However, as storage demands grow, SSDs face critical challenges in scalability, endurance, latency, and security.…

Hardware Architecture · Computer Science 2026-02-12 Tianyu Ren , Yajuan Du , Jinhua Cui , Yina Lv , Qiao Li , Chun Jason Xue

As the capacity of Solid-State Drives (SSDs) is constantly being optimised and boosted with gradually reduced cost, the SSD cluster is now widely deployed as part of the hybrid storage system in various scenarios such as cloud computing and…

Performance · Computer Science 2023-03-24 Jiashu Wu , Yang Wang , Jinpeng Wang , Hekang Wang , Taorui Lin

Solid state drives have a number of interesting characteristics. However, there are numerous file system and storage design issues for SSDs that impact the performance and device endurance. Many flash-oriented and flash-friendly file…

Operating Systems · Computer Science 2019-07-30 Viacheslav Dubeyko

With the ever-increasing amount of data generate in the world, estimated to reach over 200 Zettabytes by 2025, pressure on efficient data storage systems is intensifying. The shift from HDD to flash-based SSD provides one of the most…

Operating Systems · Computer Science 2023-07-25 Nick Tehrany , Krijn Doekemeijer , Animesh Trivedi

Hybrid Solid-State Drives (SSDs), which integrate several types of flash cells (e.g., single-level cell (SLC) and multiple-level cell (MLC)) in a single drive and enable them to convert between each other, are designed to deliver both high…

Hardware Architecture · Computer Science 2025-03-18 Qian Wei , Yi Li , Zehao Chen , Zhaoyan Shen , Dongxiao Yu , Bingzhe Li

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

Neural personalized recommendation models are used across a wide variety of datacenter applications including search, social media, and entertainment. State-of-the-art models comprise large embedding tables that have billions of parameters…

Hardware Architecture · Computer Science 2021-02-02 Mark Wilkening , Udit Gupta , Samuel Hsia , Caroline Trippel , Carole-Jean Wu , David Brooks , Gu-Yeon Wei

Storing digital information, ensuring the accuracy, steady and uninterrupted access to the data are considered as fundamental challenges in enterprise-class organizations and companies. In recent years, new types of storage systems such as…

Other Computer Science · Computer Science 2014-05-12 Arash Batni , Farshad Safaei

Over the last two decades, scientific workflow management systems (SWfMS) have emerged as a means to facilitate the design, execution, and monitoring of reusable scientific data processing pipelines. At the same time, the amounts of data…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-03-29 Marc Bux , Ulf Leser

This chapter introduces the state-of-the-art in the emerging area of combining High Performance Computing (HPC) with Big Data Analysis. To understand the new area, the chapter first surveys the existing approaches to integrating HPC with…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-01 Yuankun Fu , Fengguang Song

Existing solid state drive (SSD) simulators unfortunately lack hardware and/or software architecture models. Consequently, they are far from capturing the critical features of contemporary SSD devices. More importantly, while the…

Hardware Architecture · Computer Science 2017-09-15 Myoungsoo Jung , Jie Zhang , Ahmed Abulila , Miryeong Kwon , Narges Shahidi , John Shalf , Nam Sung Kim , Mahmut Kandemir

As deep learning models scale, they become increasingly competitive from domains spanning from computer vision to natural language processing; however, this happens at the expense of efficiency since they require increasingly more memory…

Neural and Evolutionary Computing · Computer Science 2024-01-30 Fabrizio Ottati , Chang Gao , Qinyu Chen , Giovanni Brignone , Mario R. Casu , Jason K. Eshraghian , Luciano Lavagno

The performance and capacity of solid-state drives (SSDs) are continuously improving to meet the increasing demands of modern data-intensive applications. Unfortunately, communication between the SSD controller and memory chips (e.g., 2D/3D…

The growing demand for efficient cloud storage solutions has led to the widespread adoption of Solid-State Drives (SSDs) for caching in cloud block storage systems. The management of data writes to SSD caches plays a crucial role in…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-30 Chiyu Cheng , Chang Zhou , Yang Zhao , Jin Cao

The exponential growth of DNA sequencing data has outpaced traditional heuristic-based methods, which struggle to scale effectively. Efficient computational approaches are urgently needed to support large-scale similarity search, a…

Emerging storage systems with new flash exhibit ultra-low latency (ULL) that can address performance disparities between DRAM and conventional solid state drives (SSDs) in the memory hierarchy. Considering the advanced low-latency…

Operating Systems · Computer Science 2019-12-17 Sungjoon Koh , Junhyeok Jang , Changrim Lee , Miryeong Kwon , Jie Zhang , Myoungsoo Jung

Using machine learning, especially deep learning, to facilitate biological research is a fascinating research direction. However, in addition to the standard classification or regression problems, in bioinformatics, we often need to predict…

Quantitative Methods · Quantitative Biology 2020-08-31 Yu Li

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

There is a wide range of available biological databases developed by bioinformatics experts, employing different methods to extract biological data. In this paper, we investigate and evaluate the performance of some of these methods in…

Databases · Computer Science 2022-02-08 Raja A. Moftah , Abdelsalam M. Maatuk , Richard White
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