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With quantum computers of significant size now on the horizon, we should understand how to best exploit their initially limited abilities. To this end, we aim to identify a practical problem that is beyond the reach of current classical…

Quantum Physics · Physics 2018-09-26 Andrew M. Childs , Dmitri Maslov , Yunseong Nam , Neil J. Ross , Yuan Su

Ising machines are hardware solvers which aim to find the absolute or approximate ground states of the Ising model. The Ising model is of fundamental computational interest because it is possible to formulate any problem in the complexity…

Quantum Physics · Physics 2022-04-04 Naeimeh Mohseni , Peter L. McMahon , Tim Byrnes

Quantum annealing has emerged as a promising approach for solving NP-hard optimization problems, leveraging quantum phenomena such as quantum tunneling to navigate complex energy landscapes. However, the extent to which quantum tunneling…

Quantum Physics · Physics 2026-03-02 Vishwajeet Ohal , Pierre Boulanger

Quantum annealing targets low-energy solutions of Ising/QUBO problems, but reliable assessment requires more than best-energy comparisons. This dissertation develops a benchmarking framework for D-Wave quantum annealers that combines strong…

Quantum Physics · Physics 2026-05-01 Tomasz Śmierzchalski

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

A prominent approach to solving combinatorial optimization problems on parallel hardware is Ising machines, i.e., hardware implementations of networks of interacting binary spin variables. Most Ising machines leverage second-order…

Emerging Technologies · Computer Science 2022-12-08 Connor Bybee , Denis Kleyko , Dmitri E. Nikonov , Amir Khosrowshahi , Bruno A. Olshausen , Friedrich T. Sommer

Recent years have seen significant advances in quantum/quantum-inspired technologies capable of approximately searching for the ground state of Ising spin Hamiltonians. The promise of leveraging such technologies to accelerate the solution…

Optimization and Control · Mathematics 2024-01-24 Robin Brown , David E. Bernal Neira , Davide Venturelli , Marco Pavone

Recent advances bring within reach the viability of solving combinatorial problems using a quantum annealing algorithm implemented on a purpose-built platform that exploits quantum properties. However, the question of how to tune the…

Data Structures and Algorithms · Computer Science 2014-10-21 Andrew D. King , Catherine C. McGeoch

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

The recent availability of the first commercial quantum computers has provided a promising tool to tackle NP hard problems which can only be solved heuristically with present techniques. However, it is unclear if the current state of…

Quantum Physics · Physics 2018-02-01 Hristo N. Djidjev , Guillaume Chapuis , Georg Hahn , Guillaume Rizk

Given an undirected graph, the stable set problem asks to determine the cardinality of the largest subset of pairwise non-adjacent vertices. This value is called the stability number of the graph, and its computation is an NP-hard problem.…

Optimization and Control · Mathematics 2025-11-14 Aljaž Krpan , Janez Povh , Dunja Pucher

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Quantum algorithms and complexity have recently been studied not only for discrete, but also for some numerical problems. Most attention has been paid so far to the integration problem, for which a speed-up is shown by quantum computers…

Quantum Physics · Physics 2007-05-23 Boleslaw Kacewicz

By analyzing the characteristics of hardware-native Ising Models and their performance on current and next generation quantum annealers, we provide a framework for determining the prospect of advantage utilizing adiabatic evolution compared…

Quantum Physics · Physics 2024-06-25 Salvatore Certo , Georgios Korpas , Andrew Vlasic , Philip Intallura

Quantum computing not only holds the potential to solve long-standing problems in quantum physics, but also to offer speed-ups across a broad spectrum of other fields. However, due to the noise and the limited scale of current quantum…

Quantum Physics · Physics 2024-03-05 Julien Gacon

In classical machine learning, a set of weak classifiers can be adaptively combined to form a strong classifier for improving the overall performance, a technique called adaptive boosting (or AdaBoost). However, constructing the strong…

Quantum Physics · Physics 2019-02-05 Ximing Wang , Yuechi Ma , Min-Hsiu Hsieh , Manhong Yung

An earlier work [18] proposes a method for solving the Lagrangian dual of a constrained binary quadratic programming problem via quantum adiabatic evolution using an outer approximation method. This should be an efficient prescription for…

Optimization and Control · Mathematics 2019-01-07 Sahar Karimi , Pooya Ronagh

We present a family of planted-solution benchmark instances for satisfiability (SAT) solvers and Ising optimization derived from integer factorization. Given two primes $p$ and $q$, the construction encodes the arithmetic constraints of $N…

Quantum Physics · Physics 2026-04-14 Itay Hen

Quantum annealing has the potential to provide a speedup over classical algorithms in solving optimization problems. Just as for any other quantum device, suppressing Hamiltonian control errors will be necessary before quantum annealers can…

Quantum Physics · Physics 2021-12-30 Adam Pearson , Anurag Mishra , Itay Hen , Daniel Lidar

Although many efficient heuristics have been developed to solve binary optimization problems, these typically produce correlated solutions for degenerate problems. Most notably, transverse-field quantum annealing - the heuristic employed in…

Disordered Systems and Neural Networks · Physics 2019-06-27 Zheng Zhu , Andrew J. Ochoa , Helmut G. Katzgraber