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Deconvolution is the most widely used aberration correction technique in microscopy, however most techniques assume that the aberrations are the same for each point in the image, which is rarely true. Methods for tracking spatially varying…

Optics · Physics 2025-12-02 Jakub Czuchnowski , Chuan Li , Hongli Ni , Brandon Weissbourd , Jerome Mertz

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

The goal of blind image deblurring is to recover a sharp image from a motion blurred one without knowing the camera motion. Current state-of-the-art methods have a remarkably good performance on images with no noise or very low noise…

Computer Vision and Pattern Recognition · Computer Science 2019-05-17 Jérémy Anger , Mauricio Delbracio , Gabriele Facciolo

Many problems of low-level computer vision and image processing, such as denoising, deconvolution, tomographic reconstruction or super-resolution, can be addressed by maximizing the posterior distribution of a sparse linear model (SLM). We…

Machine Learning · Statistics 2010-08-16 Matthias W. Seeger , Hannes Nickisch

In image deconvolution problems, the diagonalization of the underlying operators by means of the FFT usually yields very large speedups. When there are incomplete observations (e.g., in the case of unknown boundaries), standard…

Computer Vision and Pattern Recognition · Computer Science 2016-08-31 Miguel Simões , Luis B. Almeida , José Bioucas-Dias , Jocelyn Chanussot

The density deconvolution problem involves recovering a target density g from a sample that has been corrupted by noise. From the perspective of Le Cam's local asymptotic normality theory, we show that non-parametric density deconvolution…

Statistics Theory · Mathematics 2015-07-06 Stefan Wager

Numerous regularization methods for deformable image registration aim at enforcing smooth transformations, but are difficult to tune-in a priori and lack a clear physical basis. Physically inspired strategies have emerged, offering a sound…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Pablo Alvarez , Stéphane Cotin

Estimation of response functions is an important task in dynamic medical imaging. This task arises for example in dynamic renal scintigraphy, where impulse response or retention functions are estimated, or in functional magnetic resonance…

Machine Learning · Statistics 2017-06-22 Ondřej Tichý , Václav Šmídl

Image reconstruction based on indirect, noisy, or incomplete data remains an important yet challenging task. While methods such as compressive sensing have demonstrated high-resolution image recovery in various settings, there remain issues…

Numerical Analysis · Mathematics 2023-03-07 Jan Glaubitz , Anne Gelb , Guohui Song

Image denoising is a well-known and well studied problem, commonly targeting a minimization of the mean squared error (MSE) between the outcome and the original image. Unfortunately, especially for severe noise levels, such Minimum MSE…

Image and Video Processing · Electrical Eng. & Systems 2021-09-01 Bahjat Kawar , Gregory Vaksman , Michael Elad

In the present paper we consider the problem of Laplace deconvolution with noisy discrete observations. The study is motivated by Dynamic Contrast Enhanced imaging using a bolus of contrast agent, a procedure which allows considerable…

Statistics Theory · Mathematics 2012-07-12 Fabienne Comte , Charles-André Cuénod , Marianna Pensky , Yves Rozenholc

Mammography is using low-energy X-rays to screen the human breast and is utilized by radiologists to detect breast cancer. Typically radiologists require a mammogram with impeccable image quality for an accurate diagnosis. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Dominik Eckert , Sulaiman Vesal , Ludwig Ritschl , Steffen Kappler , Andreas Maier

Magnetic Resonance Imaging (MRI) is an essential diagnostic tool in clinical settings but its utility is often hindered by noise artifacts introduced during the imaging process. Effective denoising is critical for enhancing image quality…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Zeyun Deng , Joseph Campbell

Deep Learning based methods have emerged as the indisputable leaders for virtually all image restoration tasks. Especially in the domain of microscopy images, various content-aware image restoration (CARE) approaches are now used to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Mangal Prakash , Alexander Krull , Florian Jug

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

In this paper, we propose a fully convolutional networks for iterative non-blind deconvolution We decompose the non-blind deconvolution problem into image denoising and image deconvolution. We train a FCNN to remove noises in the gradient…

Computer Vision and Pattern Recognition · Computer Science 2016-11-22 Jiawei Zhang , Jinshan Pan , Wei-Sheng Lai , Rynson Lau , Ming-Hsuan Yang

Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…

Computer Vision and Pattern Recognition · Computer Science 2013-06-10 Ji Won Yoon

Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Takashi Hato , Pierre C. Dagher , Evan L. Nichols , Cody J. Smith , Kenneth W. Dunn , Scott Howard

Recent developments in fluorescence microscopy allow capturing high-resolution 3D images over time for living model organisms. To be able to image even large specimens, techniques like multi-view light-sheet imaging record different…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Canyu Yang , Dennis Eschweiler , Johannes Stegmaier

Medical imaging modalities including magnetic resonance imaging (MRI), computed tomography (CT), and ultrasound are essential for accurate diagnosis and treatment planning in modern healthcare. However, noise contamination during image…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Asadullah Bin Rahman , Masud Ibn Afjal , Md. Abdulla Al Mamun
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