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We address the problem of adapting robot trajectories to improve safety, comfort, and efficiency in human-robot collaborative tasks. To this end, we propose CoMOTO, a trajectory optimization framework that utilizes stochastic motion…

In this work, we present a new deterministic partition-based global optimization algorithm, HALO (Hybrid Adaptive Lipschitzian Optimization), which uses estimates of the local Lipschitz constants associated with different sub-regions of the…

Optimization and Control · Mathematics 2026-03-18 Danny D'Agostino

-Molecular simulations allow the study of properties and interactions of molecular systems. This article presents an improved version of the Adaptive Resolution Scheme that links two systems having atomistic (also called fine-grained) and…

Computational Engineering, Finance, and Science · Computer Science 2017-08-01 Iuliana Marin , Virgil Tudose , Anton Hadar , Nicolae Goga , Andrei Doncescu

Cooperative and Adaptive Cruise Control (CACC) is widely focused to enhance driving fuel-efficiency by maintaining a close following gap. The ecology of CACC could be further enhanced by adapting to the rolling terrain. However, current…

Robotics · Computer Science 2024-10-31 Mingyue Lei , Haoran Wang , Lu Xiong , Jaehyun , So , Ashish Dhamaniya , Jia Hu

We study the problem of globally optimizing the causal effect on a target variable of an unknown causal graph in which interventions can be performed. This problem arises in many areas of science including biology, operations research and…

Machine Learning · Computer Science 2022-08-26 Nicola Branchini , Virginia Aglietti , Neil Dhir , Theodoros Damoulas

We present a differentiable formulation of abstract chemical reaction networks (CRNs) that can be trained to solve a variety of computational tasks. Chemical reaction networks are one of the most fundamental computational substrates used by…

Molecular Networks · Quantitative Biology 2023-02-07 Alexander Mordvintsev , Ettore Randazzo , Eyvind Niklasson

Cooperative Coevolution (CC) effectively addresses Large-Scale Global Optimization (LSGO) via decomposition but struggles with the emerging class of Heterogeneous LSGO (H-LSGO) problems arising from real-world applications, where…

Neural and Evolutionary Computing · Computer Science 2026-04-03 Wenjie Qiu , Zixin Wang , Hongyu Fang , Zeyuan Ma , Yue-Jiao Gong

The constrained path optimization (CPO) problem takes the following input: (a) a road network represented as a directed graph, where each edge is associated with a "cost" and a "score" value; (b) a source-destination pair and; (c) a budget…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-05 Kousik Kumar Dutta , Ankita Dewan , Venkata M. V. Gunturi

In this paper we survey the primary research, both theoretical and applied, in the area of Robust Optimization (RO). Our focus is on the computational attractiveness of RO approaches, as well as the modeling power and broad applicability of…

Optimization and Control · Mathematics 2010-10-27 Dimitris Bertsimas , David B. Brown , Constantine Caramanis

Consensus-based optimization (CBO) is a powerful and versatile zero-order multi-particle method designed to provably solve high-dimensional global optimization problems, including those that are genuinely nonconvex or nonsmooth. The method…

Optimization and Control · Mathematics 2026-02-13 Massimo Fornasier , Hui Huang , Jona Klemenc , Greta Malaspina

Robust and stochastic optimal control problem (OCP) formulations allow a systematic treatment of uncertainty, but are typically associated with a high computational cost. The recently proposed zero-order robust optimization (zoRO) algorithm…

Optimization and Control · Mathematics 2023-11-09 Jonathan Frey , Yunfan Gao , Florian Messerer , Amon Lahr , Melanie Zeilinger , Moritz Diehl

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

In this work, we address the cooperation problem among large language model (LLM) based embodied agents, where agents must cooperate to achieve a common goal. Previous methods often execute actions extemporaneously and incoherently, without…

Artificial Intelligence · Computer Science 2025-03-04 Jie Liu , Pan Zhou , Yingjun Du , Ah-Hwee Tan , Cees G. M. Snoek , Jan-Jakob Sonke , Efstratios Gavves

Quadratic unconstrained binary optimization (QUBO) tasks are very important in chemistry, finance, job scheduling, and so on, which can be represented using graph structures, with the variables as nodes and the interaction between them as…

Quantum Physics · Physics 2024-04-10 Yuhan Huang , Ferris Prima Nugraha , Siyuan Jin , Yichi Zhang , Bei Zeng , Qiming Shao

Searching through chemical space is an exceptionally challenging problem because the number of possible molecules grows combinatorially with the number of atoms. Large, autoregressive models trained on databases of chemical compounds have…

Machine Learning · Computer Science 2025-10-24 Shriram Chennakesavalu , Frank Hu , Sebastian Ibarraran , Grant M. Rotskoff

Efficient Global Optimization (EGO) is the canonical form of Bayesian optimization that has been successfully applied to solve global optimization of expensive-to-evaluate black-box problems. However, EGO struggles to scale with dimension,…

Optimization and Control · Mathematics 2022-04-26 Youssef Diouane , Victor Picheny , Rodolphe Le Riche , Alexandre Scotto Di Perrotolo

This research delves into optimizing mechanism design, with an emphasis on the energy efficiency and the expansive design possibilities of reciprocating mechanisms. It investigates how to efficiently integrate Computer-Aided Design (CAD)…

Systems and Control · Electrical Eng. & Systems 2024-03-14 Abdelmajid Ben Yahya , Santiago Ramos Garces , Nick Van Oosterwyck , Annie Cuyt , Stijn Derammelaere

We investigate the optimal portfolio deleveraging (OPD) problem with permanent and temporary price impacts, where the objective is to maximize equity while meeting a prescribed debt/equity requirement. We take the real situation with cross…

Optimization and Control · Mathematics 2021-01-18 Hezhi Luo , Yuanyuan Chen , Xianye Zhang , Duan Li , Huixian Wu

Collision-free mobile robot navigation is an important problem for many robotics applications, especially in cluttered environments. In such environments, obstacles can be static or dynamic. Dynamic obstacles can additionally be…

Robotics · Computer Science 2023-02-28 Baskın Şenbaşlar , Gaurav S. Sukhatme
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