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Related papers: Single-molecule spectromicroscopy: the door into s…

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Thanks to their highly coherent emission and compact form factor, single axial mode diamond Raman lasers have been identified as a valuable asset for applications including integrated quantum technology, high resolution spectroscopy or…

Optics · Physics 2022-08-17 Georgios Stoikos , Eduardo Granados

Precise measurement of the refractive index of stable silicon isotopes $^{28}$Si, $^{29}$Si, $^{30}$Si single crystals with enrichments above 99.9 at.% and a silicon single crystal $^{nat}$Si of natural isotopic composition is performed…

Investigations that probe defects one at a time offer a unique opportunity to observe properties and dynamics that are washed out of ensemble measurements. Here we present confocal fluorescence measurements of individual defects in Al-doped…

Materials Science · Physics 2015-06-18 N. R. Jungwirth , Y. Y. Pai , H. S. Chang , E. R. MacQuarrie , G. D. Fuchs

We explore constraints on the spectral index $n$ of density fluctuations and the neutrino energy density fraction $\Omega_{HDM}$, employing data from a variety of large scale observations. The best fits occur for $n\approx 1$ and…

High Energy Physics - Phenomenology · Physics 2011-05-12 G. Dvali , Q. Shafi , R. Schaefer

Time course measurement of single molecules on a cell surface provides detailed information on the dynamics of the molecules, which is otherwise inaccessible. To extract the quantitative information, single particle tracking (SPT) is…

Quantitative Methods · Quantitative Biology 2016-01-06 Shunsuke Teraguchi , Yutaro Kumagai

The detection of single molecules has facilitated many advances in life- and material-sciences. Commonly, it founds on the fluorescence detection of single molecules, which are for example attached to the structures under study. For…

Single-molecule detection enables direct observation of individual biomolecular events, providing mechanistic insights into biological processes and offering a powerful tool for disease diagnostics. However, the fundamental scale mismatch…

Optics · Physics 2025-10-14 Guifeng Li , Chaoyang Gong

A scanning tunneling microscope (STM) can do more than atomic imaging and manipulation. Its tunneling current can also be used for the excitation of light, converting electron energy to photon energy. STM based single-molecule…

Optics · Physics 2019-01-01 Yao Zhang , Yang Zhang , Zhenchao Dong

Diffusion coefficient measurements are important for many biological and material investigations, such as particle dynamics, kinetics, and size determinations. Amongst current measurement methods, single particle tracking (SPT) offers the…

Biomolecules · Quantitative Biology 2011-07-12 Shannon Kian Zareh , Michael C. DeSantis , Jonathan Kessler , Je-Luen Li , Y. M. Wang

Label free tracking of small bio-particles such as proteins or viruses is of great utility in the study of biological processes, however such experiments are frequently hindered by weak signal strengths and a susceptibility to scattering…

Optics · Physics 2021-08-03 Joel Berk , Carl Paterson , Matthew R. Foreman

Temporal-spectral modes of light provide a fundamental window into the nature of atomic and molecular systems and offer robust means for information encoding. Methods to precisely characterize the temporal-spectral state of light at the…

Quantum Physics · Physics 2018-08-29 Alex O. C. Davis , Valérian Thiel , Michał Karpiński , Brian J. Smith

Absorption spectroscopy is widely used in sensing and astronomy to understand molecular compositions on microscopic to cosmological scales. However, typical dispersive spectroscopic techniques require multichannel detection, fundamentally…

Our ability to optically interrogate nanoscopic objects is controlled by the difference between their extinction cross sections and the diffraction limited area to which light can be confined in the far field. We show that a partially…

Optics · Physics 2016-11-17 Daniel Cole , Gavin Young , Alexander Weigel , P. Kukura

A method is proposed to pin down an unambiguous proof for single molecule surface enhanced Raman spectroscopy (SERS). The simultaneous use of two analyte molecules enables a clear confirmation of the single (or few) molecule nature of the…

Chemical Physics · Physics 2007-05-23 E. C. Le Ru , M. Meyer , P. G. Etchegoin

Due to their sub picosecond temporal resolution, coherent Raman spectroscopies have been proposed as a viable extension of Spontaneous Raman (SR) thermometry, to determine dynamics of mode specific vibrational energy content during out of…

The in situ combination of Scanning Probe Microscopies (SPM) with X-ray microbeams adds a variety of new possibilities to the panoply of synchrotron radiation techniques. In this paper we describe an optics-free AFM/STM that can be directly…

Materials Science · Physics 2009-01-09 Mario Rodrigues , Olivier Dhez , Simon Le Denmat , Joel Chevrier , Roberto Felici , Fabio Comin

Normal thermal fluctuations of the cell membrane have been studied extensively using high resolution microscopy and focused light, particularly at the peripheral regions of a cell. We use a single probe particle attached non-specifically to…

Biological Physics · Physics 2020-04-16 Rahul Vaippully , Vaibavi Ramanujan , Manoj Gopalakrishnan , Saumendra Bajpai , Basudev Roy

We discuss basics of scanning tunneling microscopy and spectroscopy (STM/S) of the superconducting state with normal and superconducting tips. We present a new method to measure the local variations in the Andreev reflection amplitude…

The detection of fluorescence with submolecular resolution enables the exploration of spatially varying photon yields and vibronic properties at the single-molecule level. By placing individual polycyclic aromatic hydrocarbon molecules into…

Mesoscale and Nanoscale Physics · Physics 2018-08-01 Jörg Kröger , Benjamin Doppagne , Fabrice Scheurer , Guillaume Schull

Terahertz time domain spectroscopy has been used to study low frequency confined acoustic phonons of silver nanoparticles embedded in poly(vinyl alcohol) matrix in the spectral range of 0.1 to 2.5 THz. The real and imaginary parts of the…

Mesoscale and Nanoscale Physics · Physics 2010-10-13 Sunil Kumar , N. Kamaraju , B. Karthikeyan , M. Tondusson , E. Freysz , A. K. Sood
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