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Sparsity promoting norms are frequently used in high dimensional regression. A limitation of such Lasso-type estimators is that the optimal regularization parameter depends on the unknown noise level. Estimators such as the concomitant…

Machine Learning · Statistics 2020-09-04 Quentin Bertrand , Mathurin Massias , Alexandre Gramfort , Joseph Salmon

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

An important task in health research is to characterize time-to-event outcomes such as disease onset or mortality in terms of a potentially high-dimensional set of risk factors. For example, prospective cohort studies of Alzheimer's disease…

Methodology · Statistics 2024-01-12 Harrison T. Reeder , Sebastien Haneuse , Kyu Ha Lee

This paper contributes to the literature on treatment effects estimation with machine learning inspired methods by studying the performance of different estimators based on the Lasso. Building on recent work in the field of high-dimensional…

Econometrics · Economics 2018-05-15 Michael Zimmert

This paper studies high-dimensional regression models with lasso when data is sampled under multi-way clustering. First, we establish convergence rates for the lasso and post-lasso estimators. Second, we propose a novel inference method…

Econometrics · Economics 2019-08-22 Harold D. Chiang , Yuya Sasaki

As a general and robust alternative to traditional mean regression models, quantile regression avoids the assumption of normally distributed errors, making it a versatile choice when modeling outcomes such as cognitive scores that typically…

Methodology · Statistics 2026-03-19 Rongke Lyu , Marina Vannucci , Suprateek Kundu

Generalized additive model is a powerful statistical learning and predictive modeling tool that has been applied in a wide range of applications. The need of high-dimensional additive modeling is eminent in the context of dealing with high…

Methodology · Statistics 2021-07-08 Kaixu Yang , Tapabrata Maiti

Finite mixture regression models are useful for modeling the relationship between response and predictors, arising from different subpopulations. In this article, we study high-dimensional predic- tors and high-dimensional response, and…

Statistics Theory · Mathematics 2016-01-07 Emilie Devijver

Longitudinal data are often plagued with sparsity of time points where measurements are available. The functional data analysis perspective has been shown to provide an effective and flexible approach to address this problem for the case…

Methodology · Statistics 2017-02-13 Matthew Dawson , Hans-Georg Müller

We propose a versatile and computationally efficient estimating equation method for a class of hierarchical multiplicative generalized linear mixed models with additive dispersion components, based on explicit modelling of the covariance…

Methodology · Statistics 2010-08-18 René Holst , Bent Jørgensen

We model time-varying network data as realizations from multivariate Gaussian distributions with precision matrices that change over time. To facilitate parameter estimation, we require not only that each precision matrix at any given time…

Methodology · Statistics 2022-03-11 Jie Jian , Peijun Sang , Mu Zhu

The parallel alternating direction method of multipliers (ADMM) algorithm is widely recognized for its effectiveness in handling large-scale datasets stored in a distributed manner, making it a popular choice for solving statistical…

Machine Learning · Statistics 2023-11-22 Xiaofei Wu , Zhimin Zhang , Zhenyu Cui

Regularized regression approaches such as the Lasso have been widely adopted for constructing sparse linear models in high-dimensional datasets. A complexity in fitting these models is the tuning of the parameters which control the level of…

Methodology · Statistics 2019-03-12 Ellis Patrick , Samuel Mueller

Smoothing is often used to improve the readability and interpretability of noisy areal data. However there are many instances where the underlying quantity is discontinuous. In this case, specific methods are needed to estimate the…

Methodology · Statistics 2025-05-20 Vivien Goepp , Jan van de Kassteele

Inferring causal relationships or related associations from observational data can be invalidated by the existence of hidden confounding. We focus on a high-dimensional linear regression setting, where the measured covariates are affected…

Methodology · Statistics 2021-07-22 Zijian Guo , Domagoj Ćevid , Peter Bühlmann

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a…

Predicting clinical variables from whole-brain neuroimages is a high dimensional problem that requires some type of feature selection or extraction. Penalized regression is a popular embedded feature selection method for high dimensional…

Methodology · Statistics 2018-02-27 Joanne C. Beer , Howard J. Aizenstein , Stewart J. Anderson , Robert T. Krafty

We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

Large-scale empirical data, the sample size and the dimension are high, often exhibit various characteristics. For example, the noise term follows unknown distributions or the model is very sparse that the number of critical variables is…

Statistics Theory · Mathematics 2018-06-18 Yuehan Yang , Hu Yang

We propose an L1-penalized algorithm for fitting high-dimensional generalized linear mixed models. Generalized linear mixed models (GLMMs) can be viewed as an extension of generalized linear models for clustered observations. This…

Computation · Statistics 2014-06-03 Jürg Schelldorfer , Lukas Meier , Peter Bühlmann