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In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

Engineered injection and extraction systems that create chaotic advection are promising procedures for enhancing mixing between two species. Mixing efficiencies vary considerably, so carefully selecting the design parameters, like pumping…

Chaotic Dynamics · Physics 2026-01-29 Carla Feistner , Francesca Ziliotto , Barbara Wohlmuth , Gabriele Chiogna

Microfluidic devices are gaining attention for their small size and ability to handle tiny fluid volumes. Mixing fluids efficiently at this scale, known as micromixing, is crucial. This article builds upon previous research by introducing a…

The behavior of proteins near interfaces is relevant for biological and medical purposes. Previous results in bulk show that, when the protein concentration increases, the proteins unfold and, at higher concentrations, aggregate. Here, we…

Soft Condensed Matter · Physics 2021-01-19 David March , Valentino Bianco , Giancarlo Franzese

Droplet-based microfluidics systems have become widely used in recent years thanks to their advantages, varying from the possibility of handling small fluid volumes to directly synthesizing and encapsulating various living forms for…

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

Mixing of reagents in microfluidics is necessary for various applications however, due to the laminar nature of flows, efficient mixing in a small span of length and time becomes difficult. The analysis of mixing of non-Newtonian fluids is…

Fluid Dynamics · Physics 2022-09-01 Anirban Roy , Avinash Kumar , Chirodeep Bakli , Gargi Das

The interactions of a protein, its phase behavior, and ultimately, its ability to function, are all influenced by the interactions between the protein and its hydration waters. Here we study proteins with a variety of sizes, shapes,…

Chemical Physics · Physics 2018-11-08 Nicholas B. Rego , Erte Xi , Amish J. Patel

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

Micro fluidized beds are basically suspensions of solid particles by an ascending fluid in a mm-scale tube, with applications in chemical and pharmaceutical processes involving powders. Although in many applications beds are polydisperse,…

Soft Condensed Matter · Physics 2024-01-22 Henrique Barbosa de Oliveira , Erick de Moraes Franklin

We address the evaluation of mixing efficiency in experiments of chaotic mixing inside an open-flow channel. Since the open flow continuously brings new fluid into the limited mixing region, it is difficult to define relevant mixing…

Soft Condensed Matter · Physics 2011-05-02 Emmanuelle Gouillart , Olivier Dauchot , Jean-Luc Thiffeault

The mixing of an impurity into a flowing fluid is an important process in many areas of science, including geophysical processes, chemical reactors, and microfluidic devices. In some cases, for example periodic flows, the concepts of…

Chaotic Dynamics · Physics 2016-02-29 G. Voth , G. Haller , J. P. Gollub

The design of strategies to generate efficient mixing is crucial for a variety of applications, particularly digital microfluidic devices that use small "discrete" fluid volumes (droplets) as fluid carriers and microreactors. In recent…

Chaotic Dynamics · Physics 2008-09-03 R. Chabreyrie , D. Vainchtein , C. Chandre , P. Singh , N. Aubry

A novel micromixing technique that exploit a thrust of droplets into the mixing interface is developed. The technique enhances the mixing by injecting immiscible droplets in a mixing channel and the methodology enables a control of the…

Fluid Dynamics · Physics 2023-03-28 Ryosuke Sakurai , Ken Yamamoto , Masahiro Motosuke

In the manufacturing process of high-performance particulate materials, viscous sintering plays a crucial role, particularly in fields such as polymer processing and additive manufacturing. The interactions between microscopic particles,…

Computational Engineering, Finance, and Science · Computer Science 2024-12-06 Xiaoxu Dai , Bo Qian , Arkadz Kirshtein , Qingcheng Yang

In this work, we assess the internal dynamics of particles in liquid-solid fluidized beds using an unresolved CFD-DEM model. We use the Nearest Neighbors Method (NNM) and the mixing index based on the principal component analysis proposed…

Fluid Dynamics · Physics 2024-06-25 Victor Oliveira Ferreira , Bruno Blais , Gabriela Cantarelli Lopes

One of the most widespread canonical devices for fluid mixing is the T-shaped mixer, in which two opposing miscible liquid streams meet at a junction and then mix along a main channel. Laminar steady and time-periodic flows in T-shaped…

Fluid Dynamics · Physics 2025-09-15 Huixin Li , Mohammad Mehdi Zamani Asl , Bastian Bäuerlein , Kerstin Avila , Duo Xu , Marc Avila

Induction time, a measure of how long one will wait for nucleation to occur, is an important parameter in quantifying nucleation kinetics and its underlying mechanisms. Due to the stochastic nature of nucleation, efficient methods for…

We study the mixing in the presence of convective flow in a porous medium. Convection is characterized by the formation of vortices and stagnation points, where the fluid interface is stretched and compressed enhancing mixing. We analyze…

Fluid Dynamics · Physics 2018-02-14 Juan J. Hidalgo , Marco Dentz

Protein folding is the intricate process by which a linear sequence of amino acids self-assembles into a unique three-dimensional structure. Protein folding kinetics is the study of pathways and time-dependent mechanisms a protein undergoes…

Machine Learning · Computer Science 2023-09-19 Vijay Arvind. R , Haribharathi Sivakumar , Brindha. R
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