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We prove existence, uniqueness, and regularity for a reaction-diffusion system of coupled bulk-surface equations on a moving domain modelling receptor-ligand dynamics in cells. The nonlinear coupling between the three unknowns is through…

Analysis of PDEs · Mathematics 2017-11-23 Amal Alphonse , Charles M. Elliott , Joana Terra

Weakly nonlinear amplitude equations are derived for the onset of spatially extended patterns on a general class of n-component bulk-surface reaction-diffusion systems in a ball, under the assumption of linear kinetics in the bulk and…

Pattern Formation and Solitons · Physics 2025-05-27 Edgardo Villar-Sepúlveda , Alan R. Champneys , Davide Cusseddu , Anotida Madzvamuse

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

We consider a bulk-membrane-coupled partial differential equation in which a single diffusion equation posed within the unit ball is coupled to a two-component reaction diffusion equation posed on the bounding unit sphere through a linear…

Pattern Formation and Solitons · Physics 2019-10-21 Daniel Gomez

A general system of several ordinary differential equations coupled with a reaction-diffusion equation in a bounded domain with zero-flux boundary condition is studied in the context of pattern formation. These initial-boundary value…

Analysis of PDEs · Mathematics 2021-10-29 Szymon Cygan , Anna Marciniak-Czochra , Grzegorz Karch , Kanako Suzuki

Signaling molecules play an important role for many cellular functions. We investigate here a general system of two membrane reaction-diffusion equations coupled to a diffusion equation inside the cell by a Robin-type boundary condition and…

Analysis of PDEs · Mathematics 2015-06-16 Andreas Rätz , Matthias Röger

Realistic examples of reaction-diffusion phenomena governing spatial and spatiotemporal pattern formation are rarely isolated systems, either chemically or thermodynamically. However, even formulations of `open' reaction-diffusion systems…

Pattern Formation and Solitons · Physics 2021-05-14 Andrew L. Krause , Václav Klika , Philip K. Maini , Denis Headon , Eamonn A. Gaffney

Originating from the pioneering study of Alan Turing, the bifurcation analysis predicting spatial pattern formation from a spatially uniform state for diffusing morphogens or chemical species that interact through nonlinear reactions is a…

Pattern Formation and Solitons · Physics 2023-01-18 Merlin Pelz , Michael J. Ward

The aim of this paper is to contribute to the understanding of the pattern formation phenomenon in reaction-diffusion equations coupled with ordinary differential equations. Such systems of equations arise, for example, from modeling of…

Analysis of PDEs · Mathematics 2016-07-15 Anna Marciniak-Czochra , Grzegorz Karch , Kanako Suzuki

Reaction-diffusion processes across layered media arise in several scientific domains such as pattern-forming E. coli on agar substrates, epidermal-mesenchymal coupling in development, and symmetry-breaking in cell polarisation. We develop…

Pattern Formation and Solitons · Physics 2020-09-18 Andrew L. Krause , Václav Klika , Jacob Halatek , Paul K. Grant , Thomas E. Woolley , Neil Dalchau , Eamonn A. Gaffney

This paper explores the classification of parameter spaces for reaction-diffusion systems of two chemical species on stationary domains. The dynamics of the system are explored both in the absence and presence of diffusion. The parameter…

Pattern Formation and Solitons · Physics 2017-01-19 Wakil Sarfaraz , Anotida Madzvamuse

On a two-dimensional circular domain, we analyze the formation of spatio-temporal patterns for a class of coupled bulk-surface reaction-diffusion models for which a passive diffusion process occurring in the interior bulk domain is linearly…

Pattern Formation and Solitons · Physics 2020-08-11 Frédéric Paquin-Lefebvre , Wayne Nagata , Michael J. Ward

We show global well-posedness and exponential stability of equilibria for a general class of nonlinear dissipative bulk-interface systems. They correspond to thermodynamically consistent gradient structure models of bulk-interface…

Analysis of PDEs · Mathematics 2020-01-06 Karoline Disser

The study of pattern-forming instabilities in reaction-diffusion systems on growing or otherwise time-dependent domains arises in a variety of settings, including applications in developmental biology, spatial ecology, and experimental…

Pattern Formation and Solitons · Physics 2022-07-11 Robert A. Van Gorder , Václav Klika , Andrew L. Krause

In this paper, we investigate the effects of stochastic resetting on diffusion in $\R^d\backslash \calU$, where $\calU$ is a bounded obstacle with a partially absorbing surface $\partial \calU$. We begin by considering a Robin boundary…

Statistical Mechanics · Physics 2022-06-29 Paul C. Bressloff

In recent decades, considerable research has been devoted to partial differential equations (PDEs) with dynamic boundary conditions. However, the physical interpretation of the parameters involved often remains unclear, which in turn limits…

Mathematical Physics · Physics 2025-10-29 Xiaobo Jing , Qi Wang

Recently, the problem of boundary stabilization for unstable linear constant-coefficient coupled reaction-diffusion systems was solved by means of the backstepping method. The extension of this result to systems with advection terms and…

Optimization and Control · Mathematics 2016-03-17 Rafael Vazquez , Miroslav Krstic

Pattern formation mechanisms of a reaction-diffusion-advection system, with one diffusivity, differential advection, and (Robin) boundary conditions of Danckwerts type, are being studied. Pattern selection requires mapping the domains of…

Pattern Formation and Solitons · Physics 2009-11-23 Arik Yochelis , Moshe Sheintuch

The bulk-surface wave pinning model is a reaction-diffusion system for studying cell polarisation. It is constituted by a surface reaction-diffusion equation, coupled to a bulk diffusion equation with a non-linear boundary condition. Cell…

Biological Physics · Physics 2022-11-01 Davide Cusseddu , Anotida Madzvamuse

This paper discusses the boundary feedback stabilization of a reaction-diffusion equation with Robin boundary conditions and in the presence of a time-varying state-delay. The proposed control design strategy is based on a…

Optimization and Control · Mathematics 2020-03-17 Hugo Lhachemi , Robert Shorten
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