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Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

Multi-object tracking remains challenging due to frequent occurrence of occlusions and outliers. In order to handle this problem, we propose an Approximation-Shrink Scheme for sequential optimization. This scheme is realized by introducing…

Computer Vision and Pattern Recognition · Computer Science 2015-12-01 Qi Guo , Le Dan , Dong Yin , Xiangyang Ji

Software performance modeling plays a crucial role in developing and maintaining software systems. A performance model analytically describes the relationship between the performance of a system and its runtime activities. This process…

Software Engineering · Computer Science 2024-11-27 Kaveh Shahedi , Heng Li , Maxime Lamothe , Foutse Khomh

Automatic detection and tracking of cells in microscopy images are major applications of computer vision technologies in both biomedical research and clinical practice. Though machine learning methods are increasingly common in these…

Computer Vision and Pattern Recognition · Computer Science 2023-12-07 Nikomidisz Eftimiu , Michal Kozubek

This paper introduces a novel framework for the automated tracking of cells, with a particular focus on the challenging situation of phase contrast microscopic videos. Our framework is based on a topology preserving variational segmentation…

Quantitative Methods · Quantitative Biology 2012-03-28 Michael Moeller , Martin Burger , Peter Dieterich , Albrecht Schwab

A novel and fast semi-automatic method for segmentation, locating and counting blood cells in an image is proposed. In this method, thresholding is used to separate the nucleus from the other parts. We also use Hough transform for circles…

Image and Video Processing · Electrical Eng. & Systems 2020-04-21 Hamed Sadeghi , Shahram Shirani , David W. Capson

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

A robust and efficient anomaly detection technique is proposed, capable of dealing with crowded scenes where traditional tracking based approaches tend to fail. Initial foreground segmentation of the input frames confines the analysis to…

Computer Vision and Pattern Recognition · Computer Science 2013-04-04 Vikas Reddy , Conrad Sanderson , Brian C. Lovell

Integer linear programming (ILP) encompasses a very important class of optimization problems that are of great interest to both academia and industry. Several algorithms are available that attempt to explore the solution space of this class…

Emerging Technologies · Computer Science 2018-08-31 Fabio L. Traversa , Massimiliano Di Ventra

Any 3D tracking algorithm has to deal with occlusions: multiple targets get so close to each other that the loss of their identities becomes likely. In the best case scenario, trajectories are interrupted, thus curbing the completeness of…

Computer Vision and Pattern Recognition · Computer Science 2018-02-19 Andrea Cavagna , Stefania Melillo , Leonardo Parisi , Federico Ricci-Tersenghi

Many signal processing problems can be solved by maximizing the fitness of a segmented model over all possible partitions of the data interval. This letter describes a simple but powerful algorithm that searches the exponentially large…

Missing data in single-cell sequencing datasets poses significant challenges for extracting meaningful biological insights. However, existing imputation approaches, which often assume uniformity and data completeness, struggle to address…

Machine Learning · Computer Science 2026-05-26 Yuyu Liu , Jiannan Yang , Ziyang Yu , Weishen Pan , Fei Wang , Tengfei Ma

Telescope networks are gaining traction due to their promise of higher resource utilization than single telescopes and as enablers of novel astronomical observation modes. However, as telescope network sizes increase, the possibility of…

Instrumentation and Methods for Astrophysics · Physics 2015-03-26 Sotiria Lampoudi , Eric Saunders , Jason Eastman

A novel technique is proposed to optimize energy efficiency for wireless networks based on hierarchical mobile clustering. The new bi-level clustering technique minimizes mutual interference and energy consumption in large-scale tracking…

Computers and Society · Computer Science 2019-02-11 Uthman Baroudi , Abdulrahman Abu Elkhail , Hesham Alfares

Lineage tracing, the tracking of living cells as they move and divide, is a central problem in biological image analysis. Solutions, called lineage forests, are key to understanding how the structure of multicellular organisms emerges. We…

Computer Vision and Pattern Recognition · Computer Science 2017-10-03 Florian Jug , Evgeny Levinkov , Corinna Blasse , Eugene W. Myers , Bjoern Andres

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

Single-cell RNA sequencing (scRNA-seq), especially temporally resolved datasets, enables genome-wide profiling of gene expression dynamics at single-cell resolution across discrete time points. However, current technologies provide only…

Genomics · Quantitative Biology 2025-11-19 Yue Ling , Peiqi Zhang , Zhenyi Zhang , Peijie Zhou

The problem of robust extraction of visual odometry from a sequence of images obtained by an eye in hand camera configuration is addressed. A novel approach toward solving planar template based tracking is proposed which performs a…

Computer Vision and Pattern Recognition · Computer Science 2014-01-21 Rafid Siddiqui , Siamak Khatibi

Cell detection is an essential task in cell image analysis. Recent deep learning-based detection methods have achieved very promising results. In general, these methods require exhaustively annotating the cells in an entire image. If some…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Kazuma Fujii , Daiki Suehiro , Kazuya Nishimura , Ryoma Bise