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Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into development and the principles that orchestrate the…

Tissues and Organs · Quantitative Biology 2018-06-13 M. D. Peters , L. D. Wittwer , A. Stopka , D. Barac , C. Lang , D. Iber

We propose a 2-dimensional cellular automaton model to simulate pedestrian traffic. It is a vmax=1 model with exclusion statistics and parallel dynamics. Long-range interactions between the pedestrians are mediated by a so called floor…

Statistical Mechanics · Physics 2009-11-07 C. Burstedde , K. Klauck , A. Schadschneider , J. Zittartz

This paper proposes an improved cellular automaton traffic flow model based on the brake light model, which takes into account that the desired time gap of vehicles is remarkably larger than one second. Although the hypothetical steady…

Cellular Automata and Lattice Gases · Physics 2015-03-23 Junfang Tian , Bin Jia , Shoufeng Ma , Chenqiang Zhu , Rui Jiang , YaoXian Ding

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

Endothelial cells are responsible for the formation of the capillary blood vessel network. We describe a system of endothelial cells by means of two-dimensional molecular dynamics simulations of point-like particles. Cells' motion is…

Soft Condensed Matter · Physics 2022-12-22 Paolo Buttà , Fiammetta Cerreti , Vito D. P. Servedio , Livio Triolo

The Cellular Automaton (CA) modeling and simulation of solid dynamics is a long-standing difficult problem. In this paper we present a new two-dimensional CA model for solid dynamics. In this model the solid body is represented by a set of…

Cellular Automata and Lattice Gases · Physics 2015-06-12 Yinfeng Dong , Guangcai Zhang , Aiguo Xu , Yanbiao Gan

Many diffusion processes in nature and society were found to be anomalous, in the sense of being fundamentally different from conventional Brownian motion. An important example is the migration of biological cells, which exhibits…

Statistical Mechanics · Physics 2018-02-13 J. M. Nava-Sedeno , H. Hatzikirou , R. Klages , A. Deutsch

Biological cells are the prototypical example of active matter. Cells sense and respond to mechanical, chemical and electrical environmental stimuli with a range of behaviors, including dynamic changes in morphology and mechanical…

Computational Engineering, Finance, and Science · Computer Science 2017-02-28 Endre Somogyi , James A. Glazier

We investigate a cellular automaton (CA) model of traffic on a bi-directional two-lane road. Our model is an extension of the one-lane CA model of {Nagel and Schreckenberg 1992}, modified to account for interactions mediated by passing, and…

Statistical Mechanics · Physics 2009-10-31 Patrice Simon , Howard A Gutowitz

Cellular automaton (CA) approach is an important theoretical framework for studying complex system behavior and has been widely applied in various research field. CA traffic flow models have the advantage of flexible evolution rules and…

Cellular Automata and Lattice Gases · Physics 2018-10-09 Junfang Tian , Chenqiang Zhu , Rui Jiang

We investigate a probabilistic cellular automaton model which has been introduced recently. This model describes single-lane traffic flow on a ring and generalizes the asymmetric exclusion process models. We study the equilibrium properties…

Condensed Matter · Physics 2009-10-22 M. Schreckenberg , A. Schadschneider , K. Nagel , N. Ito

Aerotaxis is the particular form of chemotaxis in which oxygen plays the role of both the attractant and the repellent. Aerotaxis occurs without methylation adaptation, and it leads to fast and complete aggregation toward the most favorable…

Classical Analysis and ODEs · Mathematics 2015-06-26 Barbara "Bori" C. Mazzag

We present simulations of evacuation processes using a recently introduced cellular automaton model for pedestrian dynamics. This model applies a bionics approach to describe the interaction between the pedestrians using ideas from…

Statistical Mechanics · Physics 2015-06-24 Ansgar Kirchner , Andreas Schadschneider

A coupled system of nonlinear mixed-type equations modeling early stages of angiogenesis is analyzed in a bounded domain. The system consists of stochastic differential equations describing the movement of the positions of the tip and stalk…

Analysis of PDEs · Mathematics 2022-06-24 Markus Fellner , Ansgar Jüngel

Mathematical models of cardiac electrical excitation are increasingly complex, with multiscale models seeking to represent and bridge physiological behaviours across temporal and spatial scales. The increasing complexity of these models…

Tissues and Organs · Quantitative Biology 2016-12-13 Yen Ting Lin , Eugene TY Chang , Julie Eatock , Tobias Galla , Richard H Clayton

Based on a detailed microscopic test scenario motivated by recent empirical studies of single-vehicle data, several cellular automaton models for traffic flow are compared. We find three levels of agreement with the empirical data: 1)…

Statistical Mechanics · Physics 2009-11-10 Wolfgang Knospe , Ludger Santen , Andreas Schadschneider , Michael Schreckenberg

Cardiac muscle cells can exhibit complex patterns including irregular behaviour such as chaos or (chaotic) early afterdepolarisations (EADs), which can lead to sudden cardiac death. Suitable mathematical models and their analysis help to…

Dynamical Systems · Mathematics 2021-01-15 André H. Erhardt , Susanne Solem

To accelerate the development of strategies for cartilage tissue engineering, models are necessary to study the interactions between cellular dynamics and scaffold (SC) porosity. In experiments, cells are seeded in a porous SC where over a…

Tissues and Organs · Quantitative Biology 2018-09-03 Simone Cassani , Sarah D. Olson

Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels. A…

Molecular Networks · Quantitative Biology 2019-07-26 Shubham Tripathi , Jianhua Xing , Herbert Levine , Mohit Kumar Jolly

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks - and how can…

Computational Engineering, Finance, and Science · Computer Science 2015-10-20 Dagmar Iber , Zahra Karimaddini , Erkan Ünal