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The ability to collect and analyze large amounts of data is a growing problem within the scientific community. The growing gap between data and users calls for innovative tools that address the challenges faced by big data volume, velocity…

Synthetic data generation has emerged as an invaluable solution in scenarios where real-world data collection and usage are limited by cost and scarcity. Large language models (LLMs) have demonstrated remarkable capabilities in producing…

Machine Learning · Computer Science 2025-07-22 Anh Nguyen , Sam Schafft , Nicholas Hale , John Alfaro

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu

Nowadays it is very important to maintain a high level security to ensure safe and trusted communication of information between various organizations. But secured data communication over internet and any other network is always under threat…

Cryptography and Security · Computer Science 2012-04-09 Mohammad Sazzadul Hoque , Md. Abdul Mukit , Md. Abu Naser Bikas

The emergence and development of cancer is a consequence of the accumulation over time of genomic mutations involving a specific set of genes, which provides the cancer clones with a functional selective advantage. In this work, we model…

Machine Learning · Computer Science 2017-03-10 Daniele Ramazzotti , Marco S. Nobile , Paolo Cazzaniga , Giancarlo Mauri , Marco Antoniotti

Diffusion models have significantly mitigated the impact of annotated data scarcity in remote sensing (RS). Although recent approaches have successfully harnessed these models to enable diverse and controllable Layout-to-Image (L2I)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Xianbao Hou , Yonghao He , Zeyd Boukhers , John See , Hu Su , Wei Sui , Cong Yang

Through genome-wide association studies (GWAS), disease susceptible genetic variables can be identified by comparing the genetic data of individuals with and without a specific disease. However, the discovery of these associations poses a…

Machine Learning · Computer Science 2023-08-15 Zhendong Sha , Yuanzhu Chen , Ting Hu

In computational metabolic design, it is often necessary to modify the original constraint-based metabolic networks to lead to growth-coupled production, where cell growth forces target metabolite production. However, in genome-scale…

Molecular Networks · Quantitative Biology 2024-11-20 Yier Ma , Takeyuki Tamura

Biological sequence analysis is an essential step toward building a deeper understanding of the underlying functions, structures, and behaviors of the sequences. It can help in identifying the characteristics of the associated organisms,…

Machine Learning · Computer Science 2023-03-07 Taslim Murad , Sarwan Ali , Murray Patterson

This paper focuses on pattern matching in the DNA sequence. It was inspired by a previously reported method that proposes encoding both pattern and sequence using prime numbers. Although fast, the method is limited to rather small pattern…

Computer Vision and Pattern Recognition · Computer Science 2016-11-21 Janja Paliska Soldo , Ana Sovic Krzic , and Damir Sersic

The proliferation of misinformation necessitates robust yet computationally efficient fact verification systems. While current state-of-the-art approaches leverage Large Language Models (LLMs) for generating explanatory rationales, these…

Computation and Language · Computer Science 2025-11-10 Alamgir Munir Qazi , John P. McCrae , Jamal Abdul Nasir

Exploration of complex high-dimensional spaces presents significant challenges in fields such as molecular discovery, process optimization, and supply chain management. Genetic Algorithms (GAs), while offering significant power for creating…

Machine Learning · Computer Science 2025-12-01 Mani Valleti , Aditya Raghavan , Sergei V. Kalinin

Network security has become the biggest concern in the area of cyber security because of the exponential growth in computer networks and applications. Intrusion detection plays an important role in the security of information systems or…

Cryptography and Security · Computer Science 2022-10-07 Zareen Fatima , Arshad Ali

Radio maps are essential for efficient radio resource management in future 6G and low-altitude networks. While deep learning (DL) techniques have emerged as an efficient alternative to conventional ray-tracing for radio map estimation…

Machine Learning · Computer Science 2026-02-24 Junshen Chen , Angzi Xu , Zezhong Zhang , Shiyao Zhang , Junting Chen , Shuguang Cui

Introduction: Feature selection and gene set analysis are of increasing interest in bioinformatics. While these two approaches have been developed for different purposes, we describe how some gene set analysis methods can be used to conduct…

Methodology · Statistics 2015-11-30 Suyan Tian , Chi Wang , Howard H. Chang

Distributed optimization has been widely used as one of the most efficient approaches for model training with massive samples. However, large-scale learning problems with both massive samples and high-dimensional features widely exist in…

Machine Learning · Computer Science 2022-04-26 Runxue Bao , Xidong Wu , Wenhan Xian , Heng Huang

Gene expression data represents a unique challenge in predictive model building, because of the small number of samples $(n)$ compared to the huge amount of features $(p)$. This "$n<<p$" property has hampered application of deep learning…

Machine Learning · Statistics 2018-02-13 Yunchuan Kong , Tianwei Yu

One of the notable fields in studying the genetics of cancer is disease gene identification which affects disease treatment and drug discovery. Many researches have been done in this field. Genome-wide association studies (GWAS) are one of…

Computational Engineering, Finance, and Science · Computer Science 2016-04-27 Zahra Razaghi-Moghadama , Razieh Abdollahia , Sama Goliaeib , Morteza Ebrahimia

Reconstructing the causal network in a complex dynamical system plays a crucial role in many applications, from sub-cellular biology to economic systems. Here we focus on inferring gene regulation networks (GRNs) from perturbation or gene…

Quantitative Methods · Quantitative Biology 2016-12-21 Hoi-To Wai , Anna Scaglione , Uzi Harush , Baruch Barzel , Amir Leshem

Quantitative analysis of large-scale data is often complicated by the presence of diverse subgroups, which reduce the accuracy of inferences they make on held-out data. To address the challenge of heterogeneous data analysis, we introduce…

Machine Learning · Computer Science 2021-09-01 Nazanin Alipourfard , Keith Burghardt , Kristina Lerman