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While in standard photoacoustic imaging the propagation of sound waves is modeled by the standard wave equation, our approach is based on a generalized wave equation with variable sound speed and material density, respectively. In this…

Analysis of PDEs · Mathematics 2018-04-18 Alexander Beigl , Peter Elbau , Kamran Sadiq , Otmar Scherzer

We investigate the inverse source problem for the wave equation, arising in photo- and thermoacoustic tomography. There exist quite a few theoretically exact inversion formulas explicitly expressing solution of this problem in terms of the…

Analysis of PDEs · Mathematics 2018-08-01 Ngoc Do , Leonid Kunyansky

Quantitative photo-acoustic tomography (QPAT) seeks to reconstruct a distribution of optical attenuation coefficients inside a sample from a set of time series of pressure data that is measured outside the sample. The associated inverse…

Optimization and Control · Mathematics 2019-09-04 Ashkan Javaherian , Sean Holman

The attenuation of ultrasound waves in photoacoustic and thermoacoustic imaging presents an important drawback in the applicability of these modalities. This issue has been addressed previously in the applied and theoretical literature, and…

Analysis of PDEs · Mathematics 2021-09-15 Benjamin Palacios

Practical applications of thermoacoustic tomography require numerical inversion of the spherical mean Radon transform with the centers of integration spheres occupying an open surface. Solution of this problem is needed (both in 2-D and…

Analysis of PDEs · Mathematics 2009-11-13 Leonid Kunyansky

The goal of quantitative photoacoustic tomography is to determine optical and acoustical material properties from initial pressure maps as obtained, for instance, from photoacoustic imaging. The most relevant parameters are absorption,…

Analysis of PDEs · Mathematics 2015-09-21 Wolf Naetar , Otmar Scherzer

Photo-acoustic tomography is a newly developed hybrid imaging modality that combines a high-resolution modality with a high-contrast modality. We analyze the reconstruction of diffusion and absorption parameters in an elliptic equation and…

Analysis of PDEs · Mathematics 2015-06-04 Jie Chen , Yang Yang

Almost all known image reconstruction algorithms for photoacoustic and thermoacoustic tomography assume that the acoustic waves leave the region of interest after a finite time. This assumption is reasonable if the reflections from the…

Analysis of PDEs · Mathematics 2015-06-16 L. Kunyansky , B. Holman , B. T. Cox

Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of…

Analysis of PDEs · Mathematics 2015-06-05 Kun wang , Richard Su , Alexander A. Oraevsky , Mark A. Anastasio

We consider the problem of signal reconstruction for computed tomography (CT) under a nonlinear forward model that accounts for exponential signal attenuation, a polychromatic X-ray source, general measurement noise (e.g., Poisson shot…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Mengqi Lou , Kabir Aladin Verchand , Sara Fridovich-Keil , Ashwin Pananjady

The objective of quantitative photoacoustic tomography (QPAT) is to reconstruct optical and thermodynamic properties of heterogeneous media from data of absorbed energy distribution inside the media. There have been extensive theoretical…

Medical Physics · Physics 2019-10-08 Alexander V. Mamonov , Kui Ren

Photoacoustic tomography (PAT) is a hybrid imaging modality that intends to construct high-resolution images of optical properties of heterogeneous media from measured acoustic data generated by the photoacoustic effect. To date, most of…

Numerical Analysis · Mathematics 2019-08-07 Christina Frederick , Kui Ren , Sarah Vallélian

We present an image recovery approach to improve amplitude and phase reconstruction from single shot digital holograms, using iterative reconstruction with alternating updates. This approach allows the flexibility to apply different priors…

Optics · Physics 2016-10-04 Dennis J. Lee , Charles A. Bouman , Andrew M. Weiner

This paper aims to mathematically advance the field of quantitative thermo-acoustic imaging. Given several electromagnetic data sets, we establish for the first time an analytical formula for reconstructing the absorption coefficient from…

Analysis of PDEs · Mathematics 2014-03-25 Habib Ammari , Josselin Garnier , Wenjia Jing , Loc Nguyen

In this article, we revisit iterative methods for solving the inverse problem of photoacoustic tomography in free space. Recently, there have been interesting developments on explicit formulations of the adjoint operator, demonstrating that…

Analysis of PDEs · Mathematics 2017-05-16 Markus Haltmeier , Linh V. Nguyen

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

In this paper, we describe the numerical reconstruction method for quantitative photoacoustic tomography (QPAT) based on the radiative transfer equation (RTE), which models light propagation more accurately than diffusion approximation…

Quantitative Methods · Quantitative Biology 2017-10-25 Chao Wang , Tie Zhou

The photoacoustic tomography (PAT) is a hybrid modality that combines the optics and acoustics to obtain high resolution and high contrast imaging of heterogeneous media. In this work, our objective is to study the inverse problem in the…

Numerical Analysis · Mathematics 2021-05-26 Hongkai Zhao , Yimin Zhong