Related papers: Spatial Moran models I. Stochastic tunneling in th…
A single solid tumor, composed of nearly identical cells, exhibits heterogeneous dynamics. Cells dynamics in the core is glass-like whereas those in the periphery undergo diffusive or super-diffusive behavior. Quantification of…
In this work, we investigate the population dynamics of tumor cells under therapeutic pressure. Although drug treatment initially induces a reduction in tumor burden, treatment failure frequently occurs over time due to the emergence of…
In this paper, we investigate a mathematical model describing the interactions between effector cells (E), cancer cells (T), and the IL-2 compound (IL). The model considered here is a generalization, taking into account some cross-diffusion…
We consider a discrete-time stochastic growth model on the $d$-dimensional lattice with non-negative real numbers as possible values per site. The growth model describes various interesting examples such as oriented site/bond percolation,…
The proliferation and migration dichotomy of the tumor cell invasion is examined within a two-component continuous time random walk (CTRW) model. The balance equations for the cancer cells of two phenotypes with random switching between…
We introduce a new model of random $d$-dimensional simplicial complexes, for $d\geq 2$, whose $(d-1)$-cells have bounded degrees. We show that with high probability, complexes sampled according to this model are coboundary expanders. The…
One of the hallmarks of pre-migratory tumors is the progressive loss of compact morphology. To investigate how tumors may intrinsically regulate their shape during growth, we employ a three-dimensional (3D) vertex model of multicellular…
Traditionally, it has been held that a central characteristic of stem cells is their ability to divide asymmetrically. Recent advances in inducible genetic labeling provided ample evidence that symmetric stem cell divisions play an…
The Gierer-Meinhardt system occurs in morphogenesis, where the development of an organism from a single cell is modelled. One of the steps in the development, is the formation of spatial patterns of the cell structure, starting from an…
Cell size control and homeostasis is a major topic in cell biology yet to be fully understood. Several growth laws like the timer, adder, and sizer were proposed, and mathematical approaches that model cell growth and division were…
The massive Schwinger model is studied, using a density matrix renormalization group approach to the staggered lattice Hamiltonian version of the model. Lattice sizes up to 256 sites are calculated, and the estimates in the continuum limit…
Mathematical models that describe the tumor growth process have been formulated by several authors in order to understand how cancer develops and to develop new treatment approaches. In this study, it is aimed to investigate the long-time…
In this paper, we propose a stochastic cellular automaton model of traffic flow extending two exactly solvable stochastic models, i.e., the asymmetric simple exclusion process and the zero range process. Moreover it is regarded as a…
We study existence of solutions in the variational sense for a class of stochastic phase-field models describing moving boundary problems. The models consist of stochastic reaction-diffusion equations with singular diffusion forced by a…
We take up the challenge of designing realistic computational models of large interacting cell populations. The goal is essentially to bring Gillespie's celebrated stochastic methodology to the level of an interacting population of cells.…
Let $X$ be the mosaic generated by a stationary Poisson hyperplane process $\hat X$ in ${\mathbb R}^d$. Under some mild conditions on the spherical directional distribution of $\hat X$ (which are satisfied, for example, if the process is…
We present a discrete stochastic model which represents many of the salient features of the biological process of wound healing. The model describes fronts of cells invading a wound. We have numerical results in one and two dimensions. In…
A spatiotemporal noise is assumed to reflect the environmental fluctuation in a spatially extended tumor system. We introduce firstly the structure factor to reveal the invasive tumor growth quantitatively. The homogenous environment can…
We investigate two-dimensional (2d) melting in the presence of a one-dimensional (1d) periodic potential as, for example, realized in recent experiments on 2d colloids subjected to two interfering laser beams. The topology of the phase…
The alternate row and column scaling algorithm applied to a positive $n\times n$ matrix $A$ converges to a doubly stochastic matrix $S(A)$, sometimes called the \emph{Sinkhorn limit} of $A$. For every positive integer $n$, a two parameter…