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Some recent works reveal that there are models of differential equations for the mean and variance of infected individuals that reproduce the SIS epidemic model at some point. This stochastic SIS epidemic model can be interpreted as a…

Populations and Evolution · Quantitative Biology 2020-08-07 Oğul Esen , Eduardo Fernández-Saiz , Cristina Sardón , Marcin Zając

Ordinary differential equations (ODEs) are widely used to model biological, (bio-)chemical and technical processes. The parameters of these ODEs are often estimated from experimental data using ODE-constrained optimisation. This article…

Optimization and Control · Mathematics 2015-11-06 Anna Fiedler , Fabian J. Theis , Jan Hasenauer

We investigate the effect of degree correlation on a susceptible-infected-susceptible (SIS) model with a nonlinear cooperative effect (synergy) in infectious transmissions. In a mean-field treatment of the synergistic SIS model on a bimodal…

Physics and Society · Physics 2022-09-08 Shogo Mizutaka , Kizashi Mori , Takehisa Hasegawa

We present a modelling framework for the spreading of epidemics on temporal networks from which both the individual-based and pair-based models can be recovered. The proposed temporal pair-based model that is systematically derived from…

Physics and Society · Physics 2020-11-17 Rory Humphries , Kieran Mulchrone , Jamie Tratalos , Simon More , Philipp Hövel

We study epidemic arrival times in meta-population disease models through the lens of front propagation into unstable states. We demonstrate that several features of invasion fronts in the PDE context are also relevant to the network case.…

Populations and Evolution · Quantitative Biology 2022-10-19 Ashley Armbruster , Matt Holzer , Noah Roselli , Lena Underwood

We consider the edge-based compartmental models for epidemic spread developed in Part I. We show conditions under which simpler models may be substituted for more detailed models, and in so doing we define a hierarchy of epidemic models. In…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Erik M. Volz

We investigate the effects of risk perception in a simple model of epidemic spreading. We assume that the perception of the risk of being infected depends on the fraction of neighbors that are ill. The effect of this factor is to decrease…

Populations and Evolution · Quantitative Biology 2007-12-06 Franco Bagnoli , Pietro Lio , Luca Sguanci

This paper is concerned with developing mean-field game models for the evolution of epidemics. Specifically, an agent's decision -- to be socially active in the midst of an epidemic -- is modeled as a mean-field game with health-related…

Optimization and Control · Mathematics 2021-11-23 S. Yagiz Olmez , Shubham Aggarwal , Jin Won Kim , Erik Miehling , Tamer Başar , Matthew West , Prashant G. Mehta

The dynamic behaviour of stochastic spreading processes on a network model based on k-regular graphs is investigated. The contact process and the susceptible-infected-susceptible model for the spread of epidemics are considered as prototype…

Disordered Systems and Neural Networks · Physics 2008-10-08 S. V. Fallert , S. N. Taraskin

We study the relative importance of two key control measures for epidemic spreading: endogenous social self-distancing and exogenous imposed quarantine. We use the framework of adaptive networks, moment-closure, and ordinary differential…

Populations and Evolution · Quantitative Biology 2020-10-22 Leonhard Horstmeyer , Christian Kuehn , Stefan Thurner

The manner epidemics occurs in a social network depends on various elements, with two of the most influential being the relationships among individuals in the population and the mechanism of transmission. In this paper, we assume that the…

Dynamical Systems · Mathematics 2024-05-09 Francisco J. Muñoz , Luca Meacci , Juan Carlos Nuño , Mario Primicerio

The susceptible-exposed-infectious-susceptible (SEIS) model is well-known in mathematical epidemiology as a model of infection in which there is a latent period between the moment of infection and the onset of infectiousness. The…

Probability · Mathematics 2015-10-06 Eric Foxall

Mechanistic models with differential equations are a key component of scientific applications of machine learning. Inference in such models is usually computationally demanding, because it involves repeatedly solving the differential…

Machine Learning · Statistics 2022-07-06 Jonathan Schmidt , Nicholas Krämer , Philipp Hennig

We study the spread of an SIRS-type epidemic with vaccination on network. Starting from an exact Markov description of the model, we investigate the mean epidemic lifetime by providing a sufficient condition for fast extinction that depends…

Dynamical Systems · Mathematics 2020-11-23 Stefania Ottaviano , Stefano Bonaccorsi

The epidemic spreading has been widely studied when each node may get infected by an infected neighbor with the same rate. However, the infection rate between a pair of nodes is usually heterogeneous and even correlated with their nodal…

Physics and Society · Physics 2017-02-01 Bo Qu , Huijuan Wang

Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model is a popular…

Populations and Evolution · Quantitative Biology 2017-01-23 Frank Ball , Thomas House

Neural ordinary differential equations (ODEs) provide expressive representations of invertible transport maps that can be used to approximate complex probability distributions, e.g., for generative modeling, density estimation, and Bayesian…

Machine Learning · Computer Science 2025-02-07 Youssef Marzouk , Zhi Ren , Jakob Zech

The Susceptible-Infected-Susceptible model is a canonical model for emerging disease outbreaks. Such outbreaks are naturally modeled as taking place on networks. A theoretical challenge in network epidemiology is the dynamic correlations…

Physics and Society · Physics 2016-06-29 Chao-Ran Cai , Zhi-Xi Wu , Michael Z. Q. Chen , Petter Holme , Jian-Yue Guan

The review is devoted to analysis of mathematical models used for describing epidemic processes. A main focus is done on the models that are based on partial differential equations (PDEs), especially those that were developed and used for…

Populations and Evolution · Quantitative Biology 2024-03-01 Vasyl' Davydovych , Vasyl' Dutka , Roman Cherniha

Pharmacokinetic modeling using ordinary differential equations (ODEs) has an important role in dose optimization studies, where dosing must balance sustained therapeutic efficacy with the risk of adverse side effects. Such ODE models…

Methodology · Statistics 2025-06-30 Yuxuan Zhao , Samuel W. K. Wong
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