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In the evolving landscape of ECG signal analysis, the challenge of limited transparency in machine learning models remains a significant barrier to their effective integration into clinical practice. This study addresses this issue by…

Signal Processing · Electrical Eng. & Systems 2024-12-09 Toygar Tanyel , Sezgin Atmaca , Kaan Gökçe , M. Yiğit Balık , Arda Güler , Emre Aslanger , İlkay Öksüz

We propose an integrated electromechanical model of the human heart, with focus on the left ventricle, wherein biophysically detailed models describe the different physical phenomena concurring to the cardiac function. We model the…

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. For this reason, many approaches have been developed to best estimate the cardiac muscle deformation, and to obtain a practical model to use in…

Computational Engineering, Finance, and Science · Computer Science 2014-12-09 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

Multi-channel ECG-based cardiac disorders detection has an impact on cardiac care and treatment. Limitations of existing methods included variation in ECG waveforms due to the location of electrodes, high non-linearity in the signal, and…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Suraj Kumar Behera , Debanjali Bhattacharya , Ninad Aithal , Neelam Sinha

The cardiovascular system is composed of the heart, blood and blood vessels. Regarding the heart, cardiac conditions are determined by the electrocardiogram, that is a noninvasive medical procedure. In this work, we propose autoregressive…

Voltage-sensitive fluorescence imaging is widely used to image action potential waves in the heart. However, while the electrical waves trigger mechanical contraction, imaging needs to be performed with pharmacologically…

Medical Physics · Physics 2026-03-12 Shrey Chowdhary , Jan Lebert , Shai Dickman , Charles Gordon , Jan Christoph

We present a new approach to the electromagnetic inverse problem that explicitly addresses the ambiguity associated with its ill-posed character. Rather than calculating a single ``best'' solution according to some criterion, our approach…

Neurons and Cognition · Quantitative Biology 2007-05-23 David M. Schmidt , John S. George , C. C. Wood

The electrocardiogram (ECG) has always been an important biomedical test to diagnose cardiovascular diseases. Current approaches for ECG monitoring are based on body attached electrodes leading to uncomfortable user experience. Therefore,…

Signal Processing · Electrical Eng. & Systems 2022-11-22 Jinbo Chen , Dongheng Zhang , Zhi Wu , Fang Zhou , Qibin Sun , Yan Chen

Mathematical models of cardiac electrical activity are one of the most important tools for elucidating information about the heart diagnostic. Even though it is one of the major problems in biomedical research, an efficient mathematical…

Electrocardiography (ECG) is a non-invasive tool for predicting cardiovascular diseases (CVDs). Current ECG-based diagnosis systems show promising performance owing to the rapid development of deep learning techniques. However, the label…

Signal Processing · Electrical Eng. & Systems 2023-06-21 Rushuang Zhou , Lei Lu , Zijun Liu , Ting Xiang , Zhen Liang , David A. Clifton , Yining Dong , Yuan-Ting Zhang

This work presents a biventricular electromechanical human heart model that is comprehensive and clinically relevant, integrating a realistic 3D heart geometry with both systemic and pulmonary hemodynamics. The model uses a two-way…

Medical Physics · Physics 2025-09-05 Milad Hasani , Alireza Rezania , Sam Riahi

Accelerating the acquisition of magnetic resonance imaging (MRI) is a challenging problem, and many works have been proposed to reconstruct images from undersampled k-space data. However, if the main purpose is to extract certain…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Chen Qin , Wenjia Bai , Jo Schlemper , Steffen E. Petersen , Stefan K. Piechnik , Stefan Neubauer , Daniel Rueckert

The rapid developments in advanced sensing and imaging bring about a data-rich environment, facilitating the effective modeling, monitoring, and control of complex systems. For example, the body-sensor network captures multi-channel…

Machine Learning · Computer Science 2022-02-01 Jianxin Xie , Bing Yao

Reconstructing cardiac electrical activity from body surface electric potential measurements results in the severely ill-posed inverse problem in electrocardiography. Many different regularization approaches have been proposed to improve…

Numerical Analysis · Mathematics 2025-11-04 Manuel Haas , Thomas Grandits , Thomas Pinetz , Thomas Beiert , Simone Pezzuto , Alexander Effland

Electrocardiographic imaging (ECGI) seeks to reconstruct cardiac electrical activity from body-surface potentials noninvasively. However, the associated inverse problem is severely ill-posed and requires robust regularization. While…

Numerical Analysis · Mathematics 2026-02-16 Manuel Haas , Thomas Grandits , Thomas Pinetz , Thomas Beiert , Simone Pezzuto , Alexander Effland

The forward problem in electrocardiology, computing body surface potentials from cardiac electrical activity, is traditionally solved using physics-based models such as the bidomain or monodomain equations. While accurate, these approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Shaheim Ogbomo-Harmitt , Cesare Magnetti , Chiara Spota , Jakub Grzelak , Oleg Aslanidi

Magnetoencephalography (MEG) is an imaging technique used to measure the magnetic field outside the human head produced by the electrical activity inside the brain. The MEG inverse problem, identifying the location of the electrical sources…

Computation · Statistics 2014-08-01 Zhigang Yao , William F. Eddy

We present a Bayesian approach to estimate the parameters of mathematical models of cardiac electrophysiology with quantified uncertainty. Such models capture the dynamics of the electrical signal that coordinates the muscle cell…

Numerical Analysis · Mathematics 2026-04-02 Maarten Volkaerts , Marie Cloet , Hans Dierckx , Piet Claus , Giovanni Samaey

Cardiovascular disease remains a significant problem in modern society. Among non-invasive techniques, the electrocardiogram (ECG) is one of the most reliable methods for detecting abnormalities in cardiac activities. However, ECG…

Signal Processing · Electrical Eng. & Systems 2023-03-22 Huy Pham , Konstantin Egorov , Alexey Kazakov , Semen Budennyy

Coupled oscillators are prevalent throughout the physical world. Dynamical system formulations of weakly coupled oscillator systems have proven effective at capturing the properties of real-world systems. However, these formulations usually…

Adaptation and Self-Organizing Systems · Physics 2009-06-23 Charles F. Cadieu , Kilian Koepsell