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In order to efficiently explore the chemical space of all possible small molecules, a common approach is to compress the dimension of the system to facilitate downstream machine learning tasks. Towards this end, we present a data driven…

Biomolecules · Quantitative Biology 2024-01-23 Paula Mercurio , Di Liu

Collective behaviours often need to be expressed through numerical features, e.g., for classification or imitation learning. This problem is often addressed by proposing an ad-hoc feature set for a particular swarm behaviour context,…

Robotics · Computer Science 2026-02-16 André Fialho Jesus , Jonas Kuckling

Disordered proteins play essential roles in myriad cellular processes, yet their structural characterization remains a major challenge due to their dynamic and heterogeneous nature. We here present a community-driven initiative to address…

In healthcare prediction tasks, it is essential to exploit the correlations between medical features and learn better patient health representations. Existing methods try to estimate feature correlations only from data, or increase the…

Machine Learning · Computer Science 2022-05-24 Xinyu Ma , Xu Chu , Yasha Wang , Hailong Yu , Liantao Ma , Wen Tang , Junfeng Zhao

Self-organizing complex systems typically are comprised of a large number of frequently similar components or events. Through their process, a pattern at the global-level of a system emerges solely from numerous interactions among the…

Artificial Intelligence · Computer Science 2007-05-23 Vitorino Ramos , Ajith Abraham

By creating networks of biochemical pathways, communities of micro-organisms are able to modulate the properties of their environment and even the metabolic processes within their hosts. Next-generation high-throughput sequencing has led to…

Applications · Statistics 2023-03-28 Molly G. Hayes , Morgan G. I. Langille , Hong Gu

Traditional machine learning approaches assume that data comes from a single generating mechanism, which may not hold for most real life data. In these cases, the single mechanism assumption can result in suboptimal performance. We…

Machine Learning · Computer Science 2025-01-31 Mehmet Efe Lorasdagi , Ahmet Berker Koc , Ali Taha Koc , Suleyman Serdar Kozat

Statistical estimates can often be improved by fusion of data from several different sources. One example is so-called ensemble methods which have been successfully applied in areas such as machine learning for classification and…

Physics and Society · Physics 2013-09-03 Johan Dahlin , Pontus Svenson

Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…

Populations and Evolution · Quantitative Biology 2022-01-19 Jacob Cook , Samraat Pawar , Robert G. Endres

The ubiquitous role of the cyber-infrastructures, such as the WWW, provides myriad opportunities for machine learning and its broad spectrum of application domains taking advantage of digital communication. Pattern classification and…

In this paper, we consider networks consisting of a finite number of non-overlapping communities. To extract these communities, the interaction between pairs of nodes may be sampled from a large available data set, which allows a given node…

Social and Information Networks · Computer Science 2014-02-20 Se-Young Yun , Alexandre Proutiere

Given a graph of interactions, a module (also called a community or cluster) is a subset of nodes whose fitness is a function of the statistical significance of the pairwise interactions of nodes in the module. The topic of this paper is a…

Physics and Society · Physics 2018-08-20 Bhaskar DasGupta , Devendra Desai

The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of…

Populations and Evolution · Quantitative Biology 2014-07-08 Frederick A Matsen

The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent microbiome multiomics studies, particularly paired…

Methodology · Statistics 2025-04-09 Haoran Shi , Yue Wang , Dan Cheng

With the recent growth in data availability and complexity, and the associated outburst of elaborate modelling approaches, model selection tools have become a lifeline, providing objective criteria to deal with this increasingly challenging…

Methodology · Statistics 2020-10-08 Alessandro Casa , Luca Scrucca , Giovanna Menardi

Clustering algorithms are pivotal in data analysis, enabling the organization of data into meaningful groups. However, individual clustering methods often exhibit inherent limitations and biases, preventing the development of a universal…

Neural and Evolutionary Computing · Computer Science 2024-12-13 H. Jahani , F. Zamio

We study the large sample behavior of a convex clustering framework, which minimizes the sample within cluster sum of squares under an~$\ell_1$ fusion constraint on the cluster centroids. This recently proposed approach has been gaining in…

Methodology · Statistics 2016-12-30 Peter Radchenko , Gourab Mukherjee

Human associated microbial communities exert tremendous influence over human health and disease. With modern metagenomic sequencing methods it is possible to follow the relative abundance of microbes in a community over time. These…

Quantitative Methods · Quantitative Biology 2015-06-18 Charles K. Fisher , Pankaj Mehta

Multilayer networks are a useful data structure for simultaneously capturing multiple types of relationships between a set of nodes. In such networks, each relational definition gives rise to a layer. While each layer provides its own set…

Social and Information Networks · Computer Science 2016-10-21 Natalie Stanley , Saray Shai , Dane Taylor , Peter J. Mucha

This paper is an extensive survey of literature on complex network communities and clustering. Complex networks describe a widespread variety of systems in nature and society especially systems composed by a large number of highly…

Social and Information Networks · Computer Science 2015-03-24 Biswajit Saha , Amitabha Mandal , Soumendu Bikas Tripathy , Debaprasad Mukherjee