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Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…
Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…
Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…
Photoacoustic imaging is a new non-destructive medical imaging technology based on photoacoustic effect. It can reflect the difference of light absorption energy by detecting photoacoustic signal. At present, the analysis methods of…
Photoacoustic imaging has emerged in the past decades. Compared with the traditional medical imaging mode, it has better imaging performance and has great development potential in the field of biological imaging. In traditional…
Several centimeters below the skin lie multiple biomarkers, such as glucose, oxygenation, and blood flow. Monitoring these biomarkers regularly and in a non-invasive manner would enable early insight into metabolic status and vascular…
Simulation involves predicting responses of a physical system. In this article, we simulate opto-acoustic signals generated in a three-dimensional volume due to absorption of an optical pulse. A separable computational model is developed…
In photoacoustic imaging, ultrasound waves generated by a temperature rise after illumination of light absorbing structures are measured on the sample surface. These measurements are then used to reconstruct the optical absorption. We…
Photoacoustic imaging has shown great promise for medical imaging, where optical energy absorption by blood haemoglobin is used as the contrast mechanism. A numerical method was developed for the in-silico assessment of the photoacoustic…
Quantitative photoacoustic tomography (qPAT) is an imaging technique aimed at estimating chromophore concentrations inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic propagation. The…
In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…
We present numerical simulations for modelling optoacoustic (OA) signals observed in PVA hydrogel tissue phantoms. We review the computational approach to model the underlying mechanisms, i.e. optical absorption of laser energy and acoustic…
The photoacoustic signal in a closed T-cell resonator is generated and measured using laser based photoacoustic spectroscopy. The signal is modelled using the amplitude mode expansion method, which is based on eigenmode expansion and…
In this article we characterize optoacoustic signals generated from layered tissue phantoms via short laser pulses by experimental and numerical means. In particular, we consider the case where scattering is effectively negligible and the…
Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…
We deal with the photoacoustic imaging modality using dielectric nanoparticles as contrast agents. Exciting the heterogeneous tissue, localized in a bounded domain $\Omega$, with an electromagnetic wave, at a given incident frequency,…
In deep tissue photoacoustic imaging the spatial resolution is inherently limited by the acoustic wavelength. Recently, it was demonstrated that it is possible to surpass the acoustic diffraction limit by analyzing fluctuations in a set of…
Photo-acoustic tomography is a coupled-physics (hybrid) medical imaging modality that aims to reconstruct optical parameters in biological tissues from ultrasound measurements. As propagating light gets partially absorbed, the resulting…
Photoacoustic imaging has proven to be able to detect vascularization-driven optical absorption contrast associated with tumors. In order to detect breast tumors located a few centimeter deep in tissue, a sensitive ultrasound detector is of…
Photoacoustic effect refers to the acoustic generation induced by laser irradiation, where nanosecond pulsed laser source is normally used to provide instantaneous heating and thermoelastic expansion of the sample. More generally,…