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Multiple instance learning (MIL) models have achieved remarkable success in analyzing whole slide images (WSIs) for disease classification problems. However, with regard to gigapixel WSI classification problems, current MIL models are often…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ziyu Su , Mostafa Rezapour , Usama Sajjad , Metin Nafi Gurcan , Muhammad Khalid Khan Niazi

An instance with a bad mask might make a composite image that uses it look fake. This encourages us to learn segmentation by generating realistic composite images. To achieve this, we propose a novel framework that exploits a new proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-11-14 Songmin Dai , Xiaoqiang Li , Lu Wang , Pin Wu , Weiqin Tong , Yimin Chen

Recently, semi-supervised semantic segmentation has achieved promising performance with a small fraction of labeled data. However, most existing studies treat all unlabeled data equally and barely consider the differences and training…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Zhen Zhao , Sifan Long , Jimin Pi , Jingdong Wang , Luping Zhou

We propose an approach for learning category-level semantic segmentation purely from image-level classification tags indicating presence of categories. It exploits localization cues that emerge from training classification-tasked…

Computer Vision and Pattern Recognition · Computer Science 2016-12-07 Mohammadreza Mostajabi , Nicholas Kolkin , Gregory Shakhnarovich

Whole Slide Image (WSI) analysis is a powerful method to facilitate the diagnosis of cancer in tissue samples. Automating this diagnosis poses various issues, most notably caused by the immense image resolution and limited annotations. WSIs…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Ahmet Gokberk Gul , Oezdemir Cetin , Christoph Reich , Tim Prangemeier , Nadine Flinner , Heinz Koeppl

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

We present the first fully convolutional end-to-end solution for instance-aware semantic segmentation task. It inherits all the merits of FCNs for semantic segmentation and instance mask proposal. It performs instance mask prediction and…

Computer Vision and Pattern Recognition · Computer Science 2017-04-11 Yi Li , Haozhi Qi , Jifeng Dai , Xiangyang Ji , Yichen Wei

We propose an approach to semantic segmentation that achieves state-of-the-art supervised performance when applied in a zero-shot setting. It thus achieves results equivalent to those of the supervised methods, on each of the major semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Wei Yin , Yifan Liu , Chunhua Shen , Baichuan Sun , Anton van den Hengel

This work presents a new strategy for multi-class classification that requires no class-specific labels, but instead leverages pairwise similarity between examples, which is a weaker form of annotation. The proposed method, meta…

Machine Learning · Computer Science 2019-01-04 Yen-Chang Hsu , Zhaoyang Lv , Joel Schlosser , Phillip Odom , Zsolt Kira

We present a recurrent model for semantic instance segmentation that sequentially generates binary masks and their associated class probabilities for every object in an image. Our proposed system is trainable end-to-end from an input image…

Computer Vision and Pattern Recognition · Computer Science 2019-04-15 Amaia Salvador , Miriam Bellver , Victor Campos , Manel Baradad , Ferran Marques , Jordi Torres , Xavier Giro-i-Nieto

Training a Fully Convolutional Network (FCN) for semantic segmentation requires a large number of masks with pixel level labelling, which involves a large amount of human labour and time for annotation. In contrast, web images and their…

Computer Vision and Pattern Recognition · Computer Science 2017-08-08 Tong Shen , Guosheng Lin , Lingqiao Liu , Chunhua Shen , Ian Reid

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Instance segmentation is a computer vision task where separate objects in an image are detected and segmented. State-of-the-art deep neural network models require large amounts of labeled data in order to perform well in this task. Making…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Tuomas Sormunen , Arttu Lämsä , Miguel Bordallo Lopez

In traditional multiple instance learning (MIL), both positive and negative bags are required to learn a prediction function. However, a high human cost is needed to know the label of each bag---positive or negative. Only positive bags…

Machine Learning · Computer Science 2016-03-17 Zhen Hu , Zhuyin Xue

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

The dynamic environment of laboratories and clinics, with streams of data arriving on a daily basis, requires regular updates of trained machine learning models for consistent performance. Continual learning is supposed to help train models…

Machine Learning · Computer Science 2025-08-12 Zahra Ebrahimi , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

Vision language models (VLM) pre-trained on datasets of histopathological image-caption pairs enabled zero-shot slide-level classification. The ability of VLM image encoders to extract discriminative features also opens the door for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Pablo Meseguer , Rocío del Amor , Valery Naranjo

In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Renao Yan , Qiehe Sun , Cheng Jin , Yiqing Liu , Yonghong He , Tian Guan , Hao Chen
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