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We simulate TIP4P/2005 water in the temperature range of 257 K to 318 K with time-steps $\delta =$ 0.25, 0.50, 2.00, and 4.00 fs. The density-temperature behavior obtained using 0.25 or 0.50 fs are in excellent agreement with each other but…

Soft Condensed Matter · Physics 2025-10-21 Dilipkumar N. Asthagiri , Thiago Pinheiro dos Santos , Thomas L. Beck

Kinetic energy equipartition is a premise for many deterministic and stochastic molecular dynamics methods that aim at sampling a canonical ensemble. While this is expected for real systems, discretization errors introduced by the numerical…

Computational Physics · Physics 2019-04-29 Ana J. Silveira , Charlles R. A. Abreu

The so-called thermodynamic anomalies of water form an integral part of the peculiar behaviour of this both important and ubiquitous molecule. In this paper our aim is to establish whether the recently proposed TIP4P/2005 model is capable…

We present predictions for the statistical error due to finite sampling in the presence of thermal fluctuations in molecular simulation algorithms. Specifically, we establish how these errors depend on Mach number, Knudsen number, number of…

Statistical Mechanics · Physics 2009-11-07 Nicolas Hadjiconstantinou , Alejandro L. Garcia , Martin Z. Bazant , Gang He

We simulate TIP3P water using a constrained Monte Carlo algorithm to generate electrostatic interactions eliminating the need to sum over long ranged Coulomb interactions. We study discretization errors when interpolating charges using…

Soft Condensed Matter · Physics 2009-11-11 A. C. Maggs

We present a new and improved method for simultaneous control of temperature and pressure in molecular dynamics simulations with periodic boundary conditions. The thermostat-barostat equations are build on our previously developed…

Statistical Mechanics · Physics 2014-11-20 Niels Grønbech-Jensen , Oded Farago

The model Tip4p/{\epsilon} for water is tested for the presence of thermodynamic and dy- namic anomalies. Molecular dynamic simulations for this model were performed and we show that for this system the density versus temperature at…

Soft Condensed Matter · Physics 2015-08-12 Raul Fuentes-Azcatl , Marcia C. Barbosa

In this paper we introduce adaptive time step control for simulation of evolution of ice sheets. The discretization error in the approximations is estimated using "Milne's device" by comparing the result from two different methods in a…

Computational Physics · Physics 2019-08-30 Gong Cheng , Per Lötstedt , Lina von Sydow

We study numerical methods for sampling probability measures in high dimension where the underlying model is only approximately identified with a gradient system. Extended stochastic dynamical methods are discussed which have application to…

Numerical Analysis · Mathematics 2016-03-08 Benedict Leimkuhler , Xiaocheng Shang

We investigate the temperature dependence of thermodynamic (density, isobaric heat capacity), dynamical (self-diffusion coefficient, shear viscosity), and dielectric properties of several water models, the commonly employed TIP3P water…

Soft Condensed Matter · Physics 2022-04-13 Tatiana I. Morozova , Nicolas A. Garcia , Jean-Louis Barrat

The integration time step is a critical determinant of performance in molecular dynamics simulations, governing the trade-off between speed and fidelity. Although 2 fs remains the standard in atomistic biomolecular simulations, the push for…

Biological Physics · Physics 2026-03-04 Kush Coshic , Gerhard Hummer

With the objective of demonstrating usefulness of thermostats in the study of dynamic critical phenomena in fluids, we present results for transport properties in a binary Lennard-Jones fluid that exhibits liquid-liquid phase transition.…

Statistical Mechanics · Physics 2018-04-17 Sutapa Roy , Subir K. Das

We review and compare numerical methods that simultaneously control temperature while preserving the momentum, a family of particle simulation methods commonly used for the modelling of complex fluids and polymers. The class of methods…

Computational Physics · Physics 2020-02-14 Benedict Leimkuhler , Xiaocheng Shang

Many complex fluids can be described by continuum hydrodynamic field equations, to which noise must be added in order to capture thermal fluctuations. In almost all cases, the resulting coarse-grained stochastic partial differential…

Soft Condensed Matter · Physics 2022-02-14 Michael E. Cates , Étienne Fodor , Tomer Markovich , Cesare Nardini , Elsen Tjhung

A large number of water models exists for molecular simulations. They differ in the ability to reproduce specific features of real water instead of others, like the correct temperature for the density maximum or the diffusion coefficient.…

Soft Condensed Matter · Physics 2012-06-04 Roman Shevchuk , Diego Prada-Gracia , Francesco Rao

We propose a novel discrete Poisson equation approach to estimate the statistical error of a broad class of numerical integrators for the underdamped Langevin dynamics. The statistical error refers to the mean square error of the estimator…

Numerical Analysis · Mathematics 2024-05-14 Xuda Ye , Zhennan Zhou

Reliable dynamical properties from molecular dynamics simulations require careful control of thermostatting artifacts. We systematically assess how NVE, deterministic thermostats, velocity-rescale dynamics, and stochastic Langevin-type…

Chemical Physics · Physics 2025-12-01 Frederick Heinz , Sascha Jähnigen , Joana-Lysiane Schäfer , Bettina G. Keller

In the last decades a large effort has been devoted to the study of water confined in hydrophobic geometries at the nanoscale (tubes, slit pores), because of the multiple technological applications of such systems, ranging from drugs…

Soft Condensed Matter · Physics 2019-12-23 A Zaragoza , MA Gonzalez , L Joly , I Lopez-Montero , MA Canales , AL Benavides , C Valeriani

Isothermal-isobaric molecular dynamics simulations are used to examine the microscopic structure and some properties of water-methanol liquid mixture. The TIP4P/2005 and SPC/E water models are combined with the united atom TraPPE and the…

Soft Condensed Matter · Physics 2019-03-28 M. Cruz Sanchez , H. Dominguez , O. Pizio

In this work, the uncertainties in the dielectric constants of polar liquids, computed using molecular dynamics (MD) simulations, are compared for two different calculations schemes. Expressions of the uncertainty are derived for the…

Chemical Physics · Physics 2019-11-28 Hernán R. Sánchez
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