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Single nitrogen vacancy (NV) centers in diamond have been used extensively for high-sensitivity nanoscale sensing, but conventional approaches use confocal microscopy to measure individual centers sequentially, limiting throughput and…

Nuclear spin imaging at the atomic level is essential for the understanding of fundamental biological phenomena and for applications such as drug discovery. The advent of novel nano-scale sensors has given hope of achieving the…

Quantum Physics · Physics 2015-11-25 Ashok Ajoy , Ulf Bissbort , Mikhail D. Lukin , Ronald L. Walsworth , Paola Cappellaro

We present a rapid-scanning approach to fluorescence-detected two-dimensional electronic spectroscopy that combines acousto-optic phase-modulation with digital lock-in detection. The approach shifts the signal detection window to suppress…

Parallel imaging techniques have been widely used in high-field magnetic resonance imaging (MRI). Multiple receiver coils have been shown to improve image quality and allow accelerated image acquisition. Magnetic resonance imaging at…

Medical Physics · Physics 2008-11-26 V. S. Zotev , P. L. Volegov , A. N. Matlashov , M. A. Espy , J. C. Mosher , R. H. Kraus

Soon after the first measurements of nuclear magnetic resonance (NMR) in a condensed matter system, Bloch predicted the presence of statistical fluctuations proportional to $1/\sqrt{N}$ in the polarization of an ensemble of $N$ spins. First…

Mesoscale and Nanoscale Physics · Physics 2013-10-07 P. Peddibhotla , F. Xue , H. I. T. Hauge , S. Assali , E. P. A. M. Bakkers , M. Poggio

Fourier ptychographic microscopy enables gigapixel-scale imaging, with both large field-of-view and high resolution. Using a set of low-resolution images that are recorded under varying illumination angles, the goal is to computationally…

Signal Processing · Electrical Eng. & Systems 2018-03-13 Emrah Bostan , Mahdi Soltanolkotabi , David Ren , Laura Waller

Nitrogen-vacancy (NV) centers in diamond enable quantitative magnetic imaging, yet practical implementations must balance spatial resolution against acquisition time (and thus per-pixel sensitivity). Single-NV scanning magnetometry achieves…

We propose a scheme to increase the sensitivity and thus the detection volume of nanoscale single molecule magnetic resonance imaging. The proposal aims to surpass the T1 limited detection of the sensor by taking advantage of a long-lived…

Quantum Physics · Physics 2015-11-05 Johannes N. Greiner , D. D. Bhaktavatsala Rao , Philipp Neumann , Jörg Wrachtrup

Improving resolution and sensitivity will widen possible medical applications of magnetic particle imaging. Pulsed excitation promises such benefits, at the cost of more complex hardware solutions and restrictions on drive field amplitude…

We report achieving enhanced nuclear magnetization in a magnetic resonance force microscope experiment at 0.6 tesla and 4.2 kelvin using the dynamic nuclear polarization (DNP) effect. In our experiments a microwire coplanar waveguide…

Quantum sensors based on solid-state spins provide tremendous opportunities in a wide range of fields from basic physics and chemistry to biomedical imaging. However, integrating them into a scanning probe microscope to enable practical,…

Mesoscale and Nanoscale Physics · Physics 2016-01-19 Jean-Philippe Tetienne , Alain Lombard , David A. Simpson , Cameron Ritchie , Jianing Lu , Paul Mulvaney , Lloyd C. L. Hollenberg

We demonstrate a wide-band all-optical method of nanoscale magnetic resonance (MR) spectroscopy under ambient conditions. Our method relies on cross-relaxation between a probe spin, the electronic spin of a nitrogen-vacancy centre in…

Compensated magnets are of increasing interest for both fundamental research and applications, with their net-zero magnetization leading to ultrafast dynamics and robust order. To understand and control this order, nanoscale mapping of…

Optical phase-space functions describe spatial and angular information simultaneously; examples include light fields in ray optics and Wigner functions in wave optics. Measurement of phase-space enables digital refocusing, aberration…

Optics · Physics 2017-08-02 Hsiou-Yuan Liu , Jingshan Zhong , Laura Waller

Magnetic resonance imaging (MRI) revolutionized diagnostic medicine and biomedical research by allowing a noninvasive access to spin ensembles. To enhance MRI resolution to the nanometer scale, new approaches including scanning probe…

Mesoscale and Nanoscale Physics · Physics 2019-10-23 Philip Willke , Kai Yang , Yujeong Bae , Andreas J. Heinrich , Christopher P. Lutz

Magnetic Particle Imaging (MPI) is a promising imaging modality that tracks magnetic nanoparticles (MNPs) to generate real time, high-resolution images. However, achieving an optimal balance between strong signal strength and sharp image…

Medical Physics · Physics 2025-12-18 Abuobaida M. khair , Wenjing Jiang , Moritz Wildgruber , Wenjun Xi , Xiaopeng Ma

Nuclear Magnetic Resonance (NMR) spectrometry uses electro-frequency pulses to probe the resonance of a compound's nucleus, which is then analyzed to determine its structure. The acquisition time of high-resolution NMR spectra remains a…

We observe nuclear magnetic resonance (NMR) in the fractional quantum Hall regime at Landau level filling factor $\nu=2/3$ from simultaneous measurement of longitudinal resistance and photoluminescence (PL). The dynamic nuclear spin…

Mesoscale and Nanoscale Physics · Physics 2016-08-11 K. Akiba , K. Nagase , Y. Hirayama

We introduce the first method to enable an optical amplification of a coherent Raman spectroscopy signal called radio frequency Doppler Raman spectroscopy. Doppler Raman measurements amplify the optical signals in coherent Raman…

The main disadvantage of Magnetic Resonance Imaging (MRI) are its long scan times and, in consequence, its sensitivity to motion. Exploiting the complementary information from multiple receive coils, parallel imaging is able to recover…

Numerical Analysis · Computer Science 2017-03-07 Martin Uecker
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