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Generalized estimating equation (GEE) is widely adopted for regression modeling for longitudinal data, taking account of potential correlations within the same subjects. Although the standard GEE assumes common regression coefficients among…

Methodology · Statistics 2022-07-11 Tsubasa Ito , Shonosuke Sugasawa

Tensor-based representations are being increasingly used to represent complex data types such as imaging data, due to their appealing properties such as dimension reduction and the preservation of spatial information. Recently, there is a…

Methodology · Statistics 2023-12-15 Rongke Lyu , Marina Vannucci , Suprateek Kundu

This paper introduces a novel generative encoder (GE) model for generative imaging and image processing with applications in compressed sensing and imaging, image compression, denoising, inpainting, deblurring, and super-resolution. The GE…

Image and Video Processing · Electrical Eng. & Systems 2019-06-03 Lin Chen , Haizhao Yang

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

As a general and robust alternative to traditional mean regression models, quantile regression avoids the assumption of normally distributed errors, making it a versatile choice when modeling outcomes such as cognitive scores that typically…

Methodology · Statistics 2026-03-19 Rongke Lyu , Marina Vannucci , Suprateek Kundu

We propose a novel tensor-on-tensor modeling framework that flexibly models nonlinear voxel-level relationships using Gaussian process (GP) priors, while incorporating the spatial structure of the output tensor through low-rank tensor-based…

Methodology · Statistics 2026-04-10 Yajie Liu , Hengrui Luo , Suprateek Kundu

Classical regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. Modern applications in medical imaging generate covariates of more complex form such as multidimensional arrays…

Methodology · Statistics 2013-10-22 Hua Zhou , Lexin Li , Hongtu Zhu

Large-scale neuroimaging studies have been collecting brain images of study individuals, which take the form of two-dimensional, three-dimensional, or higher dimensional arrays, also known as tensors. Addressing scientific questions arising…

Methodology · Statistics 2013-04-23 Xiaoshan Li , Hua Zhou , Lexin Li

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

Generative models (GMs) such as Generative Adversary Network (GAN) and Variational Auto-Encoder (VAE) have thrived these years and achieved high quality results in generating new samples. Especially in Computer Vision, GMs have been used in…

Machine Learning · Computer Science 2018-04-27 Honggang Zhou , Yunchun Li , Hailong Yang , Wei Li , Jie Jia

This paper describes a flexible framework for generalized low-rank tensor estimation problems that includes many important instances arising from applications in computational imaging, genomics, and network analysis. The proposed estimator…

Statistics Theory · Mathematics 2021-02-08 Rungang Han , Rebecca Willett , Anru R. Zhang

Technological advances have led to a proliferation of structured big data that have matrix-valued covariates. We are specifically motivated to build predictive models for multi-subject neuroimaging data based on each subject's brain imaging…

Methodology · Statistics 2015-05-15 Yue Hu , Genevera I. Allen

Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Ruizhe Li , Matteo Bastiani , Dorothee Auer , Christian Wagner , Xin Chen

Accurate diagnosis of neurological disorders is contingent upon advanced imaging modalities such as Magnetic Resonance Imaging (MRI), which commonly utilize sparse imaging techniques to reconstruct images from limited data, thus reducing…

Traditional network analysis focuses on single-layer networks, real-world systems often form multilayer networks with multiple relationship types. However, existing methods typically fail to capture complex inter-layer dependencies by…

Longitudinal brain imaging data facilitate the monitoring of structural and functional alterations in individual brains across time, offering essential understanding of dynamic neurobiological mechanisms. Such data improve sensitivity for…

Applications · Statistics 2026-02-04 Zhentao Yu , Jiaqi Ding , Guorong Wu , Quefeng Li

Electroencephalography (EEG) stands as a crucial tool in neuroscientific research and clinical diagnostics, providing valuable insights into the electrical activities of the brain. Traditional EEG signal processing techniques, predominantly…

Neurons and Cognition · Quantitative Biology 2024-01-12 Aryan Govil , Eric Yao , Christina R. Borao

Generalized estimating equations (GEE; Liang & Zeger 1986) for general vector regression settings are examined. When the response vectors are of mixed type (e.g. continuous-binary response pairs), the GEE approach is a semiparametric…

Methodology · Statistics 2020-10-08 Alan Huang

With the fast evolution of high-throughput technology, longitudinal gene expression experiments have become affordable and increasingly common in biomedical fields. Generalized estimating equation (GEE) approach is a widely used statistical…

Applications · Statistics 2020-08-13 Suyan Tian , Chi Wang , Mayte Suarez-Farinas
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