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We propose and implement a family of quantum-informed recursive optimization (QIRO) algorithms for combinatorial optimization problems. Our approach leverages quantum resources to obtain information that is used in problem-specific…

Variational quantum algorithms are believed to be promising for solving computationally hard problems and are often comprised of repeated layers of quantum gates. An example thereof is the quantum approximate optimization algorithm (QAOA),…

The Quantum Approximate Optimization Algorithm (QAOA), which is a variational quantum algorithm, aims to give sub-optimal solutions of combinatorial optimization problems. It is widely believed that QAOA has the potential to demonstrate…

To date, research in quantum computation promises potential for outperforming classical heuristics in combinatorial optimization. However, when aiming at provable optimality, one has to rely on classical exact methods like integer…

Quantum Physics · Physics 2025-03-13 Friedrich Wagner , Jonas Nüßlein , Frauke Liers

We propose and analyze a set of variational quantum algorithms for solving quadratic unconstrained binary optimization problems where a problem consisting of $n_c$ classical variables can be implemented on $\mathcal O(\log n_c)$ number of…

Quantum approximate optimization algorithms are hybrid quantum-classical variational algorithms designed to approximately solve combinatorial optimization problems such as the MAX-CUT problem. In spite of its potential for near-term quantum…

Quantum Physics · Physics 2024-02-27 Eunok Bae , Soojoon Lee

Quantum algorithms have emerged as a promising tool to solve combinatorial optimization problems. The quantum walk optimization algorithm (QWOA) is one such variational approach that has recently gained attention. In the broader context of…

The Quantum Approximate Optimization Algorithm (QAOA) is a standard method for combinatorial optimization with a gate-based quantum computer. The QAOA consists of a particular ansatz for the quantum circuit architecture, together with a…

Quantum Physics · Physics 2020-04-28 Li Li , Minjie Fan , Marc Coram , Patrick Riley , Stefan Leichenauer

Quadratic unconstrained binary optimization (QUBO) tasks are very important in chemistry, finance, job scheduling, and so on, which can be represented using graph structures, with the variables as nodes and the interaction between them as…

Quantum Physics · Physics 2024-04-10 Yuhan Huang , Ferris Prima Nugraha , Siyuan Jin , Yichi Zhang , Bei Zeng , Qiming Shao

We present a classical algorithm to find approximate solutions to instances of quadratic unconstrained binary optimisation. The algorithm can be seen as an analogue of quantum annealing under the restriction of a product state space, where…

Quantum Physics · Physics 2023-02-14 Joseph Bowles , Alexandre Dauphin , Patrick Huembeli , José Martinez , Antonio Acín

The quantum approximate optimization algorithm (QAOA) has been introduced as a heuristic digital quantum computing scheme to find approximate solutions of combinatorial problems with shallow circuits. We present a scheme to parallelize this…

Quantum Physics · Physics 2018-03-02 Wolfgang Lechner

Encoding combinatorial optimization problems into physically meaningful Hamiltonians with tractable energy landscapes forms the foundation of quantum optimization. Numerous works have studied such efficient encodings for the class of…

Quantum Physics · Physics 2026-02-12 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithm originally proposed to find approximate solutions to Combinatorial Optimization problems on quantum computers. However, the algorithm has also attracted interest for…

Quantum Physics · Physics 2024-02-08 Pablo Díez-Valle , Diego Porras , Juan José García-Ripoll

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

In this work, we compare the performance of the Quantum Approximate Optimization Algorithm (QAOA) with state-of-the-art classical solvers such as Gurobi and MQLib to solve the combinatorial optimization problem MaxCut on 3-regular graphs.…

Quantum Physics · Physics 2024-05-01 Danylo Lykov , Jonathan Wurtz , Cody Poole , Mark Saffman , Tom Noel , Yuri Alexeev

In this work, we review quantum approaches to combinatorial optimization, with the aim of bridging theoretical developments and industrial relevance. We first survey the main families of quantum algorithms, including Quantum Annealing, the…

Quantum Physics · Physics 2026-03-20 Hala Hawashin , Deep Nath , Marco Alberto Javarone

Quantum approximate optimization algorithm (QAOA) has shown promise in solving combinatorial optimization problems by providing quantum speedup on near-term gate-based quantum computing systems. However, QAOA faces challenges for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-24 Seongmin Kim , Vincent R. Pascuzzi , Zhihao Xu , Tengfei Luo , Eungkyu Lee , In-Saeng Suh

We consider the maximum cut and maximum independent set problems on random regular graphs in the infinite-size limit, and calculate the energy densities achieved by QAOA for high degrees up to $d=100$. Such an analysis is possible because…

Quantum Physics · Physics 2025-10-22 Elisabeth Wybo , Martin Leib

Quantum Approximate Optimization Algorithm (QAOA) is a leading candidate algorithm for solving combinatorial optimization problems on quantum computers. However, in many cases QAOA requires computationally intensive parameter optimization.…

We introduce a novel quantum optimization paradigm: the Fixed-Parameter-Count Quantum Approximate Optimization Algorithm (FPC-QAOA). It is a scalable variational framework that maintains a constant number of trainable parameters regardless…