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Determining the optimal data mixture for large language model training remains a challenging problem with an outsized impact on performance. In practice, language model developers continue to rely on heuristic exploration since no…

Large-scale network experiments is a challenging problem. Simulations, emulations, and real-world testbeds all have their advantages and disadvantages. In this paper we present LiteLab, a light-weight platform specialized for large-scale…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-12-02 Liang Wang , Jussi Kangasharju

Quality-Diversity (QD) optimization algorithms are a well-known approach to generate large collections of diverse and high-quality solutions. However, derived from evolutionary computation, QD algorithms are population-based methods which…

Neural and Evolutionary Computing · Computer Science 2022-10-11 Bryan Lim , Maxime Allard , Luca Grillotti , Antoine Cully

RNA sequencing techniques, like bulk RNA-seq and Single Cell (sc) RNA-seq, are critical tools for the biologist looking to analyze the genetic activity/transcriptome of a tissue or cell during an experimental procedure. Platforms like…

Genomics · Quantitative Biology 2024-07-08 Devam Mondal , Atharva Inamdar

We present FlexLLM, a composable High-Level Synthesis (HLS) library for rapid development of domain-specific LLM accelerators. FlexLLM exposes key architectural degrees of freedom for stage-customized inference, enabling hybrid designs that…

Hardware Architecture · Computer Science 2026-01-23 Jiahao Zhang , Zifan He , Nicholas Fraser , Michaela Blott , Yizhou Sun , Jason Cong

Hashing has been widely adopted for large-scale data retrieval in many domains, due to its low storage cost and high retrieval speed. Existing cross-modal hashing methods optimistically assume that the correspondence between training…

Machine Learning · Computer Science 2019-05-30 Xuanwu Liu , Jun Wang , Guoxian Yu , Carlotta Domeniconi , Xiangliang Zhang

Replica Exchange (RE) simulations have emerged as an important algorithmic tool for the molecular sciences. RE simulations involve the concurrent execution of independent simulations which infrequently interact and exchange information. The…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-01-22 Antons Treikalis , Andre Merzky , Haoyuan Chen , Tai-Sung Lee , Darrin M. York , Shantenu Jha

Comparative evaluation of several systems is a recurrent task in researching. It is a key step before deciding which system to use for our work, or, once our research has been conducted, to demonstrate the potential of the resulting model.…

Computation and Language · Computer Science 2026-02-24 Sergio Gómez González , Miguel Domingo , Francisco Casacuberta

Clustering plays an important role in mining big data both as a modeling technique and a preprocessing step in many data mining process implementations. Fuzzy clustering provides more flexibility than non-fuzzy methods by allowing each data…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-11-26 Nasser Ghadiri , Meysam Ghaffari , Mohammad Amin Nikbakht

WebAssembly (abbreviated as Wasm) was initially introduced for the Web but quickly extended its reach into various domains beyond the Web. To create Wasm applications, developers can compile high-level programming languages into Wasm…

Software Engineering · Computer Science 2024-10-23 Yixuan Zhang , Mugeng Liu , Haoyu Wang , Yun Ma , Gang Huang , Xuanzhe Liu

The high computational and memory requirements of large language model (LLM) inference make it feasible only with multiple high-end accelerators. Motivated by the emerging demand for latency-insensitive tasks with batched processing, this…

Large-scale distributed computing infrastructures such as the Worldwide LHC Computing Grid (WLCG) require comprehensive simulation tools for evaluating performance, testing new algorithms, and optimizing resource allocation strategies.…

Machine learning models, and deep neural networks in particular, are increasingly deployed in risk-sensitive domains such as healthcare, environmental forecasting, and finance, where reliable quantification of predictive uncertainty is…

Machine Learning · Computer Science 2026-04-07 Asena Karolin Özdemir , Lars H. Heyen , Arvid Weyrauch , Achim Streit , Markus Götz , Charlotte Debus

This work presents MeKDDaM-SAGA, computer-aided automation software for implementing a novel knowledge discovery and data mining process model that was designed for performing justifiable, traceable and reproducible metabolomics data…

Quantitative Methods · Quantitative Biology 2019-07-11 Ahmed BaniMustafa , Nigel Hardy

Modern intelligent systems researchers form hypotheses about system behavior and then run experiments using one or more independent variables to test their hypotheses. We present SIERRA, a novel framework structured around that idea for…

Artificial Intelligence · Computer Science 2022-08-17 John Harwell , Maria Gini

Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations. Ensemble-based simulations are used widely to compute a number of individual…

Computational Engineering, Finance, and Science · Computer Science 2020-09-14 Vivek Balasubramanian , Travis Jensen , Matteo Turilli , Peter Kasson , Michael Shirts , Shantenu Jha

Deep learning has achieved great success in a wide spectrum of multimedia applications such as image classification, natural language processing and multimodal data analysis. Recent years have seen the development of many deep learning…

Machine Learning · Computer Science 2021-08-06 Naili Xing , Sai Ho Yeung , Chenghao Cai , Teck Khim Ng , Wei Wang , Kaiyuan Yang , Nan Yang , Meihui Zhang , Gang Chen , Beng Chin Ooi

Building on the success of Large Language Models (LLMs), LLM-based representations have dominated the document representation landscape, achieving great performance on the document embedding benchmarks. However, the high-dimensional,…

Computation and Language · Computer Science 2025-07-10 Boshko Koloski , Senja Pollak , Roberto Navigli , Blaž Škrlj

Field emission coupled with molecular dynamics simulation (FEcMD) software package is a computational tool for studying the electron emission characteristics and the atomic structure evolution of micro- and nano-protrusions made of pure…

Computational Physics · Physics 2023-10-10 Nan Li , Xinyu Gao , Xianghui Feng , Kai Wu , Yonghong Cheng , Bing Xiao

This work introduces JEMA (Joint Embedding with Multimodal Alignment), a novel co-learning framework tailored for laser metal deposition (LMD), a pivotal process in metal additive manufacturing. As Industry 5.0 gains traction in industrial…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Joao Sousa , Roya Darabi , Armando Sousa , Frank Brueckner , Luís Paulo Reis , Ana Reis