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In the past decade, the cell-type specific connectivity and activity of local cortical networks have been characterized experimentally to some detail. In parallel, modeling has been established as a tool to relate network structure to…

Neurons and Cognition · Quantitative Biology 2011-06-29 Tobias C. Potjans , Markus Diesmann

Most nervous systems encode information about stimuli in the responding activity of large neuronal networks. This activity often manifests itself as dynamically coordinated sequences of action potentials. Since multiple electrode recordings…

Neurons and Cognition · Quantitative Biology 2011-11-09 Kristina Lisa Klinkner , Cosma Rohilla Shalizi , Marcelo F. Camperi

Dynamic functional connectivity is an effective measure for the brain's responses to continuous stimuli. We propose an inferential method to detect the dynamic changes of brain networks based on time-varying graphical models. Whereas most…

Applications · Statistics 2020-06-23 Dingjue Ji , Junwei Lu , Yiliang Zhang , Hongyu Zhao , Siyuan Gao

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

Neurons and Cognition · Quantitative Biology 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

We devised a measure based on the distributions of relative event timings of two coupled units. The measure dynamically evaluates temporal interdependencies between the two coupled units. Using this we show that even in the event of…

Chaotic Dynamics · Physics 2007-05-23 Michal Zochowski , Rhonda Dzakpasu

We propose Wake-Sleep Consolidated Learning (WSCL), a learning strategy leveraging Complementary Learning System theory and the wake-sleep phases of the human brain to improve the performance of deep neural networks for visual…

Neural and Evolutionary Computing · Computer Science 2024-01-18 Amelia Sorrenti , Giovanni Bellitto , Federica Proietto Salanitri , Matteo Pennisi , Simone Palazzo , Concetto Spampinato

Inference for functional linear models in the presence of heteroscedastic errors has received insufficient attention given its practical importance; in fact, even a central limit theorem has not been studied in this case. At issue,…

Statistics Theory · Mathematics 2024-05-27 Hyemin Yeon , Xiongtao Dai , Daniel John Nordman

This work delves into studying the synchronization in two realistic neuron models using Hodgkin-Huxley dynamics. Unlike simplistic point-like models, excitatory synapses are here randomly distributed along the dendrites, introducing strong…

Neurons and Cognition · Quantitative Biology 2024-09-17 Alessandro Fiasconaro , Michele Migliore

The latent class model is a powerful unsupervised clustering algorithm for categorical data. Many statistics exist to test the fit of the latent class model. However, traditional methods to evaluate those fit statistics are not always…

Methodology · Statistics 2018-01-30 Geert H. van Kollenburg , Joris Mulder , Jeroen K. Vermunt

Cognitive effort, defined as the relationship between cognitive load and task performance, provides insight into how individuals allocate mental resources during demanding tasks. This construct is particularly important in high-stakes…

Human-Computer Interaction · Computer Science 2026-04-13 Shayla Sharmin , Mohammad Fahim Abrar , Gael Lucero-Palacios , Aditya Raikwar , Roghayeh Leila Barmaki

Considering two independent Poisson processes, we address the question of testing equality of their respective intensities. We first propose single tests whose test statistics are U-statistics based on general kernel functions. The…

Statistics Theory · Mathematics 2012-11-15 Magalie Fromont , Béatrice Laurent , Patricia Reynaud-Bouret

Recent studies have shown that functional brain brainwork is dynamic even during rest. A common approach to modeling the brain network in whole brain resting-state fMRI is to compute the correlation between anatomical regions via sliding…

Increasing evidence suggests that cortical dynamics during wake exhibits long-range temporal correlations suitable to integrate inputs over extended periods of time to increase the signal-to-noise ratio in decision-making and working memory…

Neurons and Cognition · Quantitative Biology 2017-06-14 Christian Meisel , Andreas Klaus , Vladyslav V. Vyazovskiy , Dietmar Plenz

The role of synchronous firing in sensory coding and cognition remains controversial. While studies, focusing on its mechanistic consequences in attentional tasks, suggest that synchronization dynamically boosts sensory processing, others…

Neurons and Cognition · Quantitative Biology 2019-05-07 Siavash Ghavami , Vahid Rahmati , Farshad Lahouti , Lars Schwabe

We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

When brain signals are recorded in an electroencephalogram or some similar large-scale record of brain activity, oscillatory patterns are typically observed that are thought to reflect the aggregate electrical activity of the underlying…

Neurons and Cognition · Quantitative Biology 2013-06-04 Andre Nathan , Valmir C. Barbosa

The models in statistical physics such as an Ising model offer a convenient way to characterize stationary activity of neural populations. Such stationary activity of neurons may be expected for recordings from in vitro slices or…

Neurons and Cognition · Quantitative Biology 2017-05-05 Christian Donner , Klaus Obermayer , Hideaki Shimazaki

Partial synchronization plays a crucial role in the functioning of neuronal networks: selective, coordinated activation of neurons enables information processing that flexibly adapts to a changing computational context. Since the structure…

Neurons and Cognition · Quantitative Biology 2025-06-17 Daniil Radushev , Olesia Dogonasheva , Boris Gutkin , Denis Zakharov

Correlation matrices are widely used to analyze the interdependence of variables in various real-world scenarios. Often, a perturbation in a few variables leads to mild differences in many correlation coefficients associated with these…

Applications · Statistics 2023-03-07 Itamar Faran , Michael Peer , Shahar Arzy , Yuval Benjamini

Learning requires the traversal of inherently distinct cognitive states to produce behavioral adaptation. Yet, tools to explicitly measure these states with non-invasive imaging -- and to assess their dynamics during learning -- remain…