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We analytically address disease outbreaks in large, random networks with heterogeneous infectivity and susceptibility. The transmissibility $T_{uv}$ (the probability that infection of $u$ causes infection of $v$) depends on the infectivity…

Quantitative Methods · Quantitative Biology 2009-11-13 Joel C. Miller

In the study of epidemic dynamics a fundamental question is whether a pathogen initially affecting only one individual will give rise to a limited outbreak or to a widespread pandemic. The answer to this question crucially depends not only…

Physics and Society · Physics 2021-08-12 Alfredo De Bellis , Romualdo Pastor-Satorras , Claudio Castellano

We study the dynamics of epidemic spreading processes aimed at spontaneous dissemination of information updates in populations with complex connectivity patterns. The influence of the topological structure of the network in these processes…

Statistical Mechanics · Physics 2009-11-10 Yamir Moreno , Maziar Nekovee , Alessandro Vespignani

Many pathogens spread primarily via direct contact between infected and susceptible hosts. Thus, the patterns of contacts or contact network of a population fundamentally shapes the course of epidemics. While there is a robust and growing…

Populations and Evolution · Quantitative Biology 2012-08-01 Shweta Bansal , Lauren Ancel Meyers

The spontaneous behavioral changes of the agents during an epidemic can have significant effects on the delay and the prevalence of its spread. In this work, we study a social distancing game among the agents of a population, who determine…

Physics and Society · Physics 2020-07-13 A. -R. Lagos , I. Kordonis , G. P. Papavassilopoulos

No, they can't. Epidemic spread is characterized by exponentially growing dynamics, which are intrinsically unpredictable. The time at which the growth in the number of infected individuals halts and starts decreasing cannot be calculated…

Populations and Evolution · Quantitative Biology 2022-05-20 Mario Castro , Saúl Ares , José A. Cuesta , Susanna Manrubia

It is well known that behavioral changes in contact patterns may significantly affect the spread of an epidemic outbreak. Here we focus on simple endemic models for recurrent epidemics, by modelling the social contact rate as a function of…

Populations and Evolution · Quantitative Biology 2013-09-16 Alberto d'Onofrio , Piero Manfredi

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

The outbreak of an infectious disease in a human population can lead to individuals responding with preventive measures in an attempt to avoid getting infected. This leads to changes in contact patterns. However, as we show in this paper,…

Populations and Evolution · Quantitative Biology 2018-05-15 Ka Yin Leung , Frank Ball , David Sirl , Tom Britton

The spread of a contagious disease clearly depends on when infected individuals come into contact with susceptible ones. Such effects, however, have remained largely unexplored in the study of epidemic outbreaks. In particular, it remains…

Spreading dynamics of information and diseases are usually analyzed by using a unified framework and analogous models. In this paper, we propose a model to emphasize the essential difference between information spreading and epidemic…

Physics and Society · Physics 2015-05-28 Linyuan Lü , Duan-Bing Chen , Tao Zhou

One of the famous results of network science states that networks with heterogeneous connectivity are more susceptible to epidemic spreading than their more homogeneous counterparts. In particular, in networks of identical nodes it has been…

Physics and Society · Physics 2015-08-05 Hui Yang , Ming Tang , Thilo Gross

We present a detailed analytical and numerical study for the spreading of infections in complex population networks with acquired immunity. We show that the large connectivity fluctuations usually found in these networks strengthen…

Statistical Mechanics · Physics 2009-11-07 Yamir Moreno , Romualdo Pastor-Satorras , Alessandro Vespignani

We study epidemic spreading processes in large networks, when the spread is assisted by a small number of external agents: infection sources with bounded spreading power, but whose movement is unrestricted vis-\`a-vis the underlying network…

Social and Information Networks · Computer Science 2014-04-15 Siddhartha Banerjee , Aditya Gopalan , Abhik Kumar Das , Sanjay Shakkottai

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

The dynamic nature of system gives rise to dynamical features of epidemic spreading, such as oscillation and bistability. In this paper, by studying the epidemic spreading in growing networks, in which susceptible nodes may adaptively break…

Physics and Society · Physics 2015-03-20 Jie Zhou , Gaoxi Xiao , Siew Ann Cheong , Xiuju Fu , Lim Soon Wong , Stefan Ma , Tee Hiang Cheng

We present a local spread model of disease transmission on a regular network and compare different control options ranging from treating the whole population to local control in a well-defined neighborhood of an infectious individual.…

Biological Physics · Physics 2015-05-30 Katarzyna Oles , Ewa Gudowska-Nowak , Adam Kleczkowski

Stochasticity and spatial heterogeneity are of great interest recently in studying the spread of an infectious disease. The presented method solves an inverse problem to discover the effectively decisive topology of a heterogeneous network…

Artificial Intelligence · Computer Science 2015-03-13 Yoshiharu Maeno

Current understanding of the critical outbreak condition on temporal networks relies on approximations (time scale separation, discretization) that may bias the results. We propose a theoretical framework to compute the epidemic threshold…

Physics and Society · Physics 2018-02-08 Eugenio Valdano , Michele Re Fiorentin , Chiara Poletto , Vittoria Colizza