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The work discusses the use of machine learning algorithms for anomaly detection in medical image analysis and how the performance of these algorithms depends on the number of annotators and the quality of labels. To address the issue of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Hieu H. Pham , Khiem H. Le , Tuan V. Tran , Ha Q. Nguyen

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

Cancer detection and classification from gigapixel whole slide images of stained tissue specimens has recently experienced enormous progress in computational histopathology. The limitation of available pixel-wise annotated scans shifted the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Mehdi Naouar , Gabriel Kalweit , Ignacio Mastroleo , Philipp Poxleitner , Marc Metzger , Joschka Boedecker , Maria Kalweit

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Building an accurate computer-aided diagnosis system based on data-driven approaches requires a large amount of high-quality labeled data. In medical imaging analysis, multiple expert annotators often produce subjective estimates about…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Khiem H. Le , Tuan V. Tran , Hieu H. Pham , Hieu T. Nguyen , Tung T. Le , Ha Q. Nguyen

We apply deep learning (DL) on Magnetic resonance spectroscopy (MRS) data for the task of brain tumor detection. Medical applications often suffer from data scarcity and corruption by noise. Both of these problems are prominent in our data…

Machine Learning · Computer Science 2021-12-17 Diyuan Lu , Gerhard Kurz , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Medical image classification involves thresholding of labels that represent malignancy risk levels. Usually, a task defines a single threshold, and when developing computer-aided diagnosis tools, a single network is trained per such…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Vadim Ratner , Yoel Shoshan , Tal Kachman

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Density of mitotic figures in histologic sections is a prognostically relevant characteristic for many tumours. Due to high inter-pathologist variability, deep learning-based algorithms are a promising solution to improve tumour…

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Learning algorithms normally assume that there is at most one annotation or label per data point. However, in some scenarios, such as medical diagnosis and on-line collaboration,multiple annotations may be available. In either case,…

Machine Learning · Computer Science 2012-03-19 Yan Yan , Romer Rosales , Glenn Fung , Jennifer Dy

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Medical image datasets and their annotations are not growing as fast as their equivalents in the general domain. This makes translation from the newest, more data-intensive methods that have made a large impact on the vision field…

Computer Vision and Pattern Recognition · Computer Science 2022-10-14 Tom van Sonsbeek , Xiantong Zhen , Dwarikanath Mahapatra , Marcel Worring

Multi-instance multi-label (MIML) learning is a challenging problem in many aspects. Such learning approaches might be useful for many medical diagnosis applications including breast cancer detection and classification. In this study subset…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Baris Gecer , Ozge Yalcinkaya , Onur Tasar , Selim Aksoy

Predicting all applicable labels for a given image is known as multi-label classification. Compared to the standard multi-class case (where each image has only one label), it is considerably more challenging to annotate training data for…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Elijah Cole , Oisin Mac Aodha , Titouan Lorieul , Pietro Perona , Dan Morris , Nebojsa Jojic

The development of medical science greatly depends on the increased utilization of machine learning algorithms. By incorporating machine learning, the medical imaging field can significantly improve in terms of the speed and accuracy of the…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Angona Biswas , MD Abdullah Al Nasim , Md Shahin Ali , Ismail Hossain , Md Azim Ullah , Sajedul Talukder

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

The task of multimodal cancer detection is to determine the locations and categories of lesions by using different imaging techniques, which is one of the key research methods for cancer diagnosis. Recently, deep learning-based object…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Yan Tian , Zhaocheng Xu , Yujun Ma , Weiping Ding , Ruili Wang , Zhihong Gao , Guohua Cheng , Linyang He , Xuran Zhao

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios
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