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In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…
Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…
We present a new inner-outer iterative algorithm for edge enhancement in imaging problems. At each outer iteration, we formulate a Tikhonov-regularized problem where the penalization is expressed in the 2-norm and involves a regularization…
In this paper, we present a dimension reduction method to reduce the dimension of parameter space and state space and efficiently solve inverse problems. To this end, proper orthogonal decomposition (POD) and radial basis function (RBF) are…
In this paper, we propose a novel large deformation diffeomorphic registration algorithm to align high angular resolution diffusion images (HARDI) characterized by orientation distribution functions (ODFs). Our proposed algorithm seeks an…
The use of Fourier methods in wave-front reconstruction can significantly reduce the computation time for large telescopes with a high number of degrees of freedom. However, Fourier algorithms for discrete data require a rectangular data…
Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…
Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…
The probabilistic diffusion model (DM), generating content by inferencing through a recursive chain structure, has emerged as a powerful framework for visual generation. After pre-training on enormous data, the model needs to be properly…
This article introduces a new methodology for reconstructing the white matter fiber pathways of brain in diffusion MRI. Usually, the signal intensity values will be lesser in the direction of higher diffusivity. The proposed approach picks…
We present a new algorithm, FRiM (FRactal Iterative Method), aiming at the reconstruction of the optical wavefront from measurements provided by a wavefront sensor. As our application is adaptive optics on extremely large telescopes, our…
Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…
Despite today's prevalence of ultrasound imaging in medicine, ultrasound signal-to-noise ratio is still affected by several sources of noise and artefacts. Moreover, enhancing ultrasound image quality involves balancing concurrent factors…
In the last decade diffusion MRI has become a powerful tool to non-invasively study white-matter integrity in the brain. Recently many research groups have focused their attention on multi-shell spherical acquisitions with the aim of…
Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…
Magnetic Resonance Imaging (MRI) is a powerful medical imaging modality, but unfortunately suffers from long scan times which, aside from increasing operational costs, can lead to image artifacts due to patient motion. Motion during the…
Reconstructing high-quality magnetic resonance images (MRI) from undersampled raw data is of great interest from both technical and clinical point of views. To this date, however, it is still a mathematically and computationally challenging…
Recently, diffusion models (DM) have been applied in magnetic resonance imaging (MRI) super-resolution (SR) reconstruction, exhibiting impressive performance, especially with regard to detailed reconstruction. However, the current DM-based…
Models of diffusion MRI within a voxel are useful for making inferences about the properties of the tissue and inferring fiber orientation distribution used by tractography algorithms. A useful model must fit the data accurately. However,…
Parallel MRI is a fast imaging technique that enables the acquisition of highly resolved images in space. It relies on $k$-space undersampling and multiple receiver coils with complementary sensitivity profiles in order to reconstruct a…