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Structural modularity is a pervasive feature of biological neural networks, which have been linked to several functional and computational advantages. Yet, the use of modular architectures in artificial neural networks has been relatively…

Neural and Evolutionary Computing · Computer Science 2024-06-11 Mani Hamidi , Sina Khajehabdollahi , Emmanouil Giannakakis , Tim Schäfer , Anna Levina , Charley M. Wu

The concept of robustness of regulatory networks has been closely related to the nature of the interactions among genes, and the capability of pattern maintenance or reproducibility. Defining this robustness property is a challenging task,…

Molecular Networks · Quantitative Biology 2007-10-24 Madalena Chave , Eduardo D. Sontag , Anirvan M. Sengupta

We explore the interplay between the topological relevance of a neuron and its dynamical traces in experimental cultured neuronal networks. We monitor the growth and development of these networks to characterise the evolution of their…

Adaptation and Self-Organizing Systems · Physics 2023-07-14 A. Tlaie , L. M. Ballesteros-Esteban , I. Leyva , I. Sendina-Nadal

Constraints placed upon the phenotypes of organisms result from their interactions with the environment. Over evolutionary timescales, these constraints feed back onto smaller molecular subnetworks comprising the organism. The evolution of…

Molecular Networks · Quantitative Biology 2015-06-10 Cameron Smith , Ximo Pechuan , Raymond S. Puzio , Daniel Biro , Aviv Bergman

Systems as diverse as genetic networks or the world wide web are best described as networks with complex topology. A common property of many large networks is that the vertex connectivities follow a scale-free power-law distribution. This…

Disordered Systems and Neural Networks · Physics 2015-06-25 Albert-Laszlo Barabasi , Reka Albert

The changing topology of a network is driven by the need to maintain or optimize network function. As this function is often related to moving quantities such as traffic, information, etc. efficiently through the network the structure of…

Physics and Society · Physics 2023-11-28 Annika King , Dallas Smith , Benjamin Webb

In this paper we investigate networks whose evolution is governed by the interaction of a random assembly process and an optimization process. In the first process, new nodes are added one at a time and form connections to randomly selected…

Disordered Systems and Neural Networks · Physics 2011-05-16 Markus Brede

The collective dynamics of a network of coupled excitable systems in response to an external stimulus depends on the topology of the connections in the network. Here we develop a general theoretical approach to study the effects of network…

Disordered Systems and Neural Networks · Physics 2013-10-22 Daniel B. Larremore , Woodrow L. Shew , Juan G. Restrepo

The theory of complex networks and of disordered systems is used to study the stability and dynamical properties of a simple model of material flow networks defined on random graphs. In particular we address instabilities that are…

Disordered Systems and Neural Networks · Physics 2009-11-13 Kartik Anand , Tobias Galla

Structural hierarchy, in which materials possess distinct features on multiple length scales, is ubiquitous in nature; diverse biological materials, such as bone, cellulose, and muscle, have as many as ten hierarchical levels. Structural…

Soft Condensed Matter · Physics 2019-06-19 Jonathan Michel , Peter Yunker

The interaction networks of biological systems are known to take on several non-random structural properties, some of which are believed to positively influence system robustness. Researchers are only starting to understand how these…

Neural and Evolutionary Computing · Computer Science 2011-02-08 James M. Whitacre , Ruhul A. Sarker , Q. Tuan Pham

The stable functionality of networked systems is a hallmark of their natural ability to coordinate between their multiple interacting components. Yet, strikingly, real-world networks seem random and highly irregular, apparently lacking any…

Adaptation and Self-Organizing Systems · Physics 2023-04-25 Chandrakala Meena , Chittaranjan Hens , Suman Acharyya , Simcha Haber , Stefano Boccaletti , Baruch Barzel

Mechanisms of pattern formation---of which the Turing instability is an archetype---constitute an important class of dynamical processes occurring in biological, ecological and chemical systems. Recently, it has been shown that the Turing…

Disordered Systems and Neural Networks · Physics 2019-06-19 Sayat Mimar , Mariamo Mussa Juane , Juyong Park , Alberto P. Munuzuri , Gourab Ghoshal

We propose the concepts of distributed robustness and r-robustness, well adapted to functional genetics. Then we discuss the robustness of the relaxation time using a chemical reaction description of genetic and signalling networks. First,…

Molecular Networks · Quantitative Biology 2011-11-09 A. N. Gorban , O. Radulescu

The functioning of many biochemical networks is often robust -- remarkably stable under changes in external conditions and internal reaction parameters. Much recent work on robustness and evolvability has focused on the structure of neutral…

Quantitative Methods · Quantitative Biology 2011-03-15 Bryan C. Daniels , Yan-Jiun Chen , James P. Sethna , Ryan N. Gutenkunst , Christopher R. Myers

Networks are fundamental for our understanding of complex systems. Interactions between individual nodes in networks generate network motifs - small recurrent patterns that can be considered the network's building-block components,…

Dynamical Systems · Mathematics 2022-09-14 Miri Adler , Ruslan Medzhitov

Robustness to mutations and noise has been shown to evolve through stabilizing selection for optimal phenotypes in model gene regulatory networks. The ability to evolve robust mutants is known to depend on the network architecture. How do…

Molecular Networks · Quantitative Biology 2008-07-07 Volkan Sevim , Per Arne Rikvold

It is often claimed that the entropy of a network's degree distribution is a proxy for its robustness. Here, we clarify the link between degree distribution entropy and giant component robustness to node removal by showing that the former…

Physics and Society · Physics 2022-09-12 Chris Jones , Karoline Wiesner

A classic measure of ecological stability describes the tendency of a community to return to equilibrium after small perturbation. While many advances show how the network structure of these communities severely constrains such tendencies,…

Populations and Evolution · Quantitative Biology 2015-06-09 Gang Yan , Neo D. Martinez , Yang-Yu Liu

Topology and weights are closely related in weighted complex networks and this is reflected in their modular structure. We present a simple network model where the weights are generated dynamically and they shape the developing topology. By…

Physics and Society · Physics 2008-01-30 J. M. Kumpula , J. -P. Onnela , J. Saramaki , K. Kaski , J. Kertesz
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