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Consideration is given to the methods of gaining experimental data on the substances which constitute a part of multicomponent samples to be measured. The methods are applicable to the samples comprising an arbitrary number of components;…
Strain engineering is widely used in material science to tune the (opto-)electronic properties of materials and enhance the performance of devices. Two-dimensional atomic crystals are a versatile playground to study the influence of strain,…
Antibody drugs are usually formulated as highly-concentrated solutions, which would easily generate oligomer and aggregation, resulting in loss of efficacy. Although low pH increases the colloidal dispersion of antibodies, acid denaturation…
Zernike's phase contrast microscopy (PCM) is among the most widely used techniques for observing phase objects, but it lacks quantitative nature, as it cannot directly provide phase information. Current methods for computationally…
Prostate cancer is a prevalent malignancy among men aged 50 and older. Current diagnostic methods primarily rely on blood tests, PSA:Prostate-Specific Antigen levels, and Digital Rectal Examinations (DRE). However, these methods suffer from…
One of the most powerful approaches to imaging at the nanometer or subnanometer length scale is coherent diffraction imaging using X-ray sources. For amorphous (non-crystalline) samples, the raw data can be interpreted as the modulus of the…
In this work, issues in phase retrieval in the coherent diffractive imaging (CDI) technique, from discussion on parameters for setting up a CDI experiment to evaluation of the goodness of the final reconstruction, are discussed. The…
This work explores the use of computer vision for image segmentation and classification of medical fluid samples in transparent containers (for example, tubes, syringes, infusion bags). Handling fluids such as infusion fluids, blood, and…
Neutrinos are the most abundant fundamental matter particles in the Universe and play a crucial role in particle physics and cosmology. Neutrino oscillation, discovered about 25 years ago, reveals that the three known species mix with each…
Quantitative phase analysis is one of the major applications of X-ray powder diffraction. The essential principle of quantitative phase analysis is that the diffraction intensity of a component phase in a mixture is proportional to its…
Investigation of organic molecular films by a method Raman of a spectroscopy is carried out. It is shown, that values of frequencies of lines in a spectrum of the lattice oscillations of the molecular films are depressed in comparison with…
Interpreting spectroscopy data is a critical bottleneck in automating chemical research and industrial characterization. Particularly within infrared (IR) spectroscopy, identifying compounds in complex, liquid-phase chemical mixtures…
The objective of this article was developing an automated tool for routine clinical practice to estimate urinary stone composition from CT images based on the density of all constituent voxels. A total of 118 stones for which the…
The challenge of imaging low-density objects in an electron microscope without causing beam damage is significant in modern TEM. This is especially true for life science imaging, where the sample, rather than the instrument, still…
Fluorescent detection of proteins is a popular method of detection allying sensitivity, linearity and compatibility with mass spectrometry. Among the numerous methods described in the literature, staining with ruthenium II…
Plasmonic sensing is an established technology for real-time biomedical diagnostics and air-quality monitoring. While intensity and wavelength tracking are the most commonly used interrogation methods for Surface Plasmon Resonance (SPR),…
Explainable Artificial Intelligence (AI) in the form of an interpretable and semiautomatic approach to stage grading ocular pathologies such as Diabetic retinopathy, Hypertensive retinopathy, and other retinopathies on the backdrop of major…
Raman spectroscopy is a powerful analytical tool with applications ranging from quality control to cutting edge biomedical research. One particular area which has seen tremendous advances in the past decade is the development of powerful…
The KArlsruhe TRItium Neutrino (KATRIN) experiment is a next generation, model independent, large scale tritium beta-decay experiment to determine the effective electron anti-neutrino mass by investigating the kinematics of tritium…
Bulk glass formation occurs over a very small part of phase space, and "good" glasses (which form even at low quench rates ~ 10K/sec) select an even smaller part of that accessible phase space. An axiomatic theory provides the physical…