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Biomolecular networks have already found great utility in characterizing complex biological systems arising from pair-wise interactions amongst biomolecules. Here, we review how graph theoretical approaches can be applied not only for a…

Molecular Networks · Quantitative Biology 2018-12-03 Heeralal Janwa , Steven E. Massey , Julian Velev , Bud Mishra

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

The structure of the graph defined by the interactions in a Boolean network can determine properties of the asymptotic dynamics. For instance, considering the asynchronous dynamics, the absence of positive cycles guarantees the existence of…

Discrete Mathematics · Computer Science 2022-06-24 Adrien Richard , Elisa Tonello

Identifiability conditions for single or multiple modules in a dynamic network specify under which conditions the considered modules can be uniquely recovered from the second-order statistical properties of the measured signals. Conditions…

Systems and Control · Electrical Eng. & Systems 2021-10-28 Shengling Shi , Xiaodong Cheng , Paul M. J. Van den Hof

Homophily -- the tendency of individuals to interact with similar others -- shapes how networks form and function. Yet existing approaches typically collapse homophily to a single scale, either one parameter for the whole network or one per…

Physics and Society · Physics 2025-12-16 Abbas K. Rizi , Riccardo Michielan , Clara Stegehuis , Mikko Kivelä

Neural networks for structured data like graphs have been studied extensively in recent years. To date, the bulk of research activity has focused mainly on static graphs. However, most real-world networks are dynamic since their topology…

Machine Learning · Computer Science 2020-03-03 Changmin Wu , Giannis Nikolentzos , Michalis Vazirgiannis

It is common knowledge that a key dynamical characteristic of a network is its spectrum (the collection of all eigenvalues of the network's weighted adjacency matrix). In \cite{BW10} we demonstrated that it is possible to reduce a network,…

Dynamical Systems · Mathematics 2015-06-05 Leonid Bunimovich , Benjamin Webb

Results and tools on discrete interaction networks are often concerned with Boolean variables, whereas considering more than two levels is sometimes useful. Multivalued networks can be converted to partial Boolean maps, in a way that…

Discrete Mathematics · Computer Science 2018-12-11 Elisa Tonello

Genetic regulatory networks are defined by their topology and by a multitude of continuously adjustable parameters. Here we present a class of simple models within which the relative importance of topology vs. interaction strengths becomes…

Molecular Networks · Quantitative Biology 2013-08-02 Mikhail Tikhonov , William Bialek

Many real-world networks such as social networks consist of strategic agents. The topology of these networks often plays a crucial role in determining the ease and speed with which certain information driven tasks can be accomplished.…

Social and Information Networks · Computer Science 2017-07-03 Swapnil Dhamal , Y. Narahari

Social learning algorithms provide models for the formation of opinions over social networks resulting from local reasoning and peer-to-peer exchanges. Interactions occur over an underlying graph topology, which describes the flow of…

Signal Processing · Electrical Eng. & Systems 2023-03-15 Valentina Shumovskaia , Konstantinos Ntemos , Stefan Vlaski , Ali H. Sayed

Interaction graphs provide an important qualitative modeling approach for System Biology. This paper presents a novel approach for construction of interaction graph with the help of Boolean function decomposition. Each decomposition part…

Systems and Control · Computer Science 2014-09-26 Jayanta Kumar Das , Ranjeet Kumar Rout , Pabitra Pal Choudhury

The perspective we take on a system determines the features and properties of this system that we are focusing on. It determines where we search for causes to explain the effects on the system that we observe. It determines the terms in…

Other Computer Science · Computer Science 2016-10-28 Mathilde Noual

In this paper, we examine the controllability of Laplacian dynamic networks on cographs. Cographs appear in modeling a wide range of networks and include as special instances, the threshold graphs. In this work, we present necessary and…

Optimization and Control · Mathematics 2020-05-25 Shima Sadat Mousavi , Mohammad Haeri , Mehran Mesbahi

This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model. Often Boolean models are much simpler to understand than complex…

Molecular Networks · Quantitative Biology 2011-05-10 Franziska Hinkelmann , Reinhard Laubenbacher

Controlling real-world networked systems, including ecological, biomedical, and engineered networks that exhibit higher-order interactions, remains challenging due to inherent nonlinearities and large system scales. Despite extensive…

Optimization and Control · Mathematics 2026-03-23 Joshua Pickard , Xin Mao , Can Chen

Bayesian networks, and especially their structures, are powerful tools for representing conditional independencies and dependencies between random variables. In applications where related variables form a priori known groups, chosen to…

Machine Learning · Statistics 2017-06-02 Pekka Parviainen , Samuel Kaski

A dynamical network, a graph whose nodes are dynamical systems, is usually characterized by a large dimensional space which is not always accesible due to the impossibility of measuring all the variables spanning the state space. Therefore,…

Chaotic Dynamics · Physics 2019-07-25 Irene Sendiña-Nadal , Christophe Letellier

We study the target control problem of asynchronous Boolean networks, to identify a set of nodes, the perturbation of which can drive the dynamics of the network from any initial state to the desired steady state (or attractor). We are…

Systems and Control · Electrical Eng. & Systems 2020-06-04 Cui Su , Jun Pang

In addition to the emergent complexity of patterns that appears when many agents come in interaction, it is also useful to characterize the dynamical processes that lead to their self-organization. A set of ergodic invariants is identified…

adap-org · Physics 2007-05-23 R. Vilela Mendes