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We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize…

Machine Learning · Computer Science 2018-07-10 Matthew Yung , Eli T. Brown , Alexander Rasin , Jacob D. Furst , Daniela S. Raicu

The quality control of printed circuit boards (PCBs) is paramount in advancing electronic device technology. While numerous machine learning methodologies have been utilized to augment defect detection efficiency and accuracy, previous…

Machine Learning · Computer Science 2024-09-17 Ka Nam Canaan Law , Mingshuo Yu , Lianglei Zhang , Yiyi Zhang , Peng Xu , Jerry Gao , Jun Liu

Raw nanopore signal analysis is a common approach in genomics to provide fast and resource-efficient analysis without translating the signals to bases (i.e., without basecalling). However, existing solutions cannot interpret raw signals…

In modern manufacturing, most products are conforming. Few products are nonconforming with different defect types. The identification of defect types can help further root cause diagnosis of production lines. With the sensing technology…

Machine Learning · Computer Science 2024-12-10 Juan Du , Yukun Xie , Chen Zhang

Memory forensics is a powerful technique commonly adopted to investigate compromised machines and to detect stealthy computer attacks that do not store data on non-volatile storage. To employ this technique effectively, the analyst has to…

Cryptography and Security · Computer Science 2025-07-29 Andrea Oliveri , Davide Balzarotti

Motivation: Detection of structural variants (SV) from the alignment of sample DNA reads to the reference genome is an important problem in understanding human diseases. Long reads that can span repeat regions, along with an accurate…

Genomics · Quantitative Biology 2023-01-25 Dhaivat Joshi , Suhas Diggavi , Mark J. P. Chaisson , Sreeram Kannan

Current OCR systems are based on deep learning models trained on large amounts of data. Although they have shown some ability to generalize to unseen data, especially in detection tasks, they can struggle with recognizing low-quality data.…

Plant phenotyping is typically a time-consuming and expensive endeavor, requiring large groups of researchers to meticulously measure biologically relevant plant traits, and is the main bottleneck in understanding plant adaptation and the…

We address unsupervised dependency parsing by building an ensemble of diverse existing models through post hoc aggregation of their output dependency parse structures. We observe that these ensembles often suffer from low robustness against…

Computation and Language · Computer Science 2025-04-22 Behzad Shayegh , Hobie H. -B. Lee , Xiaodan Zhu , Jackie Chi Kit Cheung , Lili Mou

Estimating species and gene trees from sequence data is challenging. Gene tree estimation is often hampered by low phylogenetic signal in alignments, leading to inaccurate trees. Species tree estimation is complicated by incomplete lineage…

Populations and Evolution · Quantitative Biology 2025-11-06 Ashu Gupta

Given genetic variations and various phenotypical traits, such as Magnetic Resonance Imaging (MRI) features, we consider two important and related tasks in biomedical research: i)to select genetic and phenotypical markers for disease…

Machine Learning · Computer Science 2013-10-17 Shandian Zhe , Zenglin Xu , Yuan Qi

Motivation: Despite significant advances in Third-Generation Sequencing (TGS) technologies, Next-Generation Sequencing (NGS) technologies remain dominant in the current sequencing market. This is due to the lower error rates and richer…

Information Theory · Computer Science 2023-04-04 Jia Wang , Yi Niu , Tianyi Xu , Mingming Ma , Dahua Gao , Guangming Shi

Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine. However, existing techniques for {\it de novo} genome assembly,…

This paper considers the problem of matching fragment to organism using its complete genome. Our method is based on the probability measure representation of a genome. We first demonstrate that these probability measures can be modelled as…

Biological Physics · Physics 2009-11-07 V. V. Anh , K. S. Lau , Z. G. Yu

In genomics, pattern matching against a sequence of nucleotides plays a pivotal role for DNA sequence alignment and comparing genomes. This helps tackling some diseases, such as cancer in humans. The complexity of searching biological…

Quantitative Methods · Quantitative Biology 2017-10-04 Fereshte Mozafari , Hossein Babashah , Somayyeh Koohi , Zahra Kavehvash

This paper presents a new, parallel implementation of clustering and demonstrates its utility in greatly speeding up the process of identifying homologous proteins. Clustering is a technique to reduce the number of comparison needed to find…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-29 Stuart Byma , Akash Dhasade , Adrian Altenhoff , Christophe Dessimoz , James R. Larus

We analyse a maximum-likelihood approach for combining phylogenetic trees into a larger `supertree'. This is based on a simple exponential model of phylogenetic error, which ensures that ML supertrees have a simple combinatorial description…

Populations and Evolution · Quantitative Biology 2007-08-17 Mike Steel , Allen Rodrigo

Machine learning classification systems are susceptible to poor performance when trained with incorrect ground truth labels, even when data is well-curated by expert annotators. As machine learning becomes more widespread, it is…

Machine Learning · Computer Science 2026-01-16 Zan Chaudhry , Noam H. Rotenberg , Brian Caffo , Craig K. Jones , Haris I. Sair

Collecting large-scale medical datasets with fine-grained annotations is time-consuming and requires experts. For this reason, weakly supervised learning aims at optimising machine learning models using weaker forms of annotations, such as…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Gabriele Valvano , Andrea Leo , Sotirios A. Tsaftaris

Paired image-text data with subtle variations in-between (e.g., people holding surfboards vs. people holding shovels) hold the promise of producing Vision-Language Models with proper compositional understanding. Synthesizing such training…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Haoxin Li , Boyang Li
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