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In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Machine Learning · Computer Science 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Partially recorded data are frequently encountered in many applications and usually clustered by first removing incomplete cases or features with missing values, or by imputing missing values, followed by application of a clustering…

Methodology · Statistics 2021-10-20 Emily M. Goren , Ranjan Maitra

In model-based-clustering mixture models are used to group data points into clusters. A useful concept introduced for Gaussian mixtures by Malsiner Walli et al (2016) are sparse finite mixtures, where the prior distribution on the weight…

Methodology · Statistics 2018-08-23 Sylvia Frühwirth-Schnatter , Gertraud Malsiner-Walli

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

Methodology · Statistics 2012-11-12 Michael A. Newton , Lisa M. Chung

Graph-based clustering methods have demonstrated the effectiveness in various applications. Generally, existing graph-based clustering methods first construct a graph to represent the input data and then partition it to generate the…

Machine Learning · Computer Science 2019-12-17 Yuheng Jia , Hui Liu , Junhui Hou , Sam Kwong

In longitudinal studies, it is not uncommon to make multiple attempts to collect a measurement after baseline. Recording whether these attempts are successful provides useful information for the purposes of assessing missing data…

Methodology · Statistics 2023-05-10 Michael J. Daniels , Minji Lee , Wei Feng

Clustering mixed data presents numerous challenges inherent to the very heterogeneous nature of the variables. A clustering algorithm should be able, despite of this heterogeneity, to extract discriminant pieces of information from the…

Machine Learning · Computer Science 2022-05-10 Robin Fuchs , Denys Pommeret , Cinzia Viroli

In some contexts, mixture models can fit certain variables well at the expense of others in ways beyond the analyst's control. For example, when the data include some variables with non-trivial amounts of missing values, the mixture model…

Methodology · Statistics 2016-09-06 Maria DeYoreo , Jerome P. Reiter , D. Sunshine Hillygus

Most published studies on the statistical analysis of count data generated by next-generation sequencing technologies have paid surprisingly little attention on cluster analysis. We present a statistical methodology (DGEclust) for…

Quantitative Methods · Quantitative Biology 2015-03-24 Dimitrios V Vavoulis , Margherita Francescatto , Peter Heutink , Julian Gough

We consider the problem of clustering grouped data for which the observations may include group-specific variables in addition to the variables that are shared across groups. This type of data is common in cancer genomics where the…

Methodology · Statistics 2025-09-30 Arhit Chakrabarti , Yang Ni , Debdeep Pati , Bani K. Mallick

Gene expression data is often collected in time series experiments, under different experimental conditions. There may be genes that have very different gene expression profiles over time, but that adjust their gene expression patterns in…

Methodology · Statistics 2021-12-02 Susana Conde , Shahin Tavakoli , Daphne Ezer

There is a rich literature on clustering functional data with applications to time-series modeling, trajectory data, and even spatio-temporal applications. However, existing methods routinely perform global clustering that enforces…

Methodology · Statistics 2024-12-16 Tsung-Hung Yao , Suprateek Kundu

Dirichlet process (DP) mixture models provide a flexible Bayesian framework for density estimation. Unfortunately, their flexibility comes at a cost: inference in DP mixture models is computationally expensive, even when conjugate…

Machine Learning · Computer Science 2009-07-13 Hal Daumé

Joint alignment of a collection of functions is the process of independently transforming the functions so that they appear more similar to each other. Typically, such unsupervised alignment algorithms fail when presented with complex data…

Machine Learning · Computer Science 2012-10-19 Marwan A. Mattar , Allen R. Hanson , Erik G. Learned-Miller

Modelling and forecasting homogeneous age-specific mortality rates of multiple countries could lead to improvements in long-term forecasting. Data fed into joint models are often grouped according to nominal attributes, such as geographic…

Methodology · Statistics 2022-01-05 Chen Tang , Han Lin Shang , Yanrong Yang

We formulate a novel technique for the detection of functional clusters in discrete event data. The advantage of this algorithm is that no prior knowledge of the number of functional groups is needed, as our procedure progressively combines…

Neurons and Cognition · Quantitative Biology 2015-05-13 S. Feldt , J. Waddell , V. L. Hetrick , J. D. Berke , M. Zochowski

Recent studies show that ensemble methods enhance the stability and robustness of unsupervised learning. These approaches are successfully utilized to construct multiple clustering and combine them into a one representative consensus…

Neural and Evolutionary Computing · Computer Science 2018-06-01 Elaheh Rashedi , Abdolreza Mirzaei

We propose the CliPS procedure when fitting Bayesian mixture models in the context of model-based clustering to identify the cluster distributions while simultaneously assessing the suitability of a cluster solution and validating the…

Methodology · Statistics 2026-03-03 Gertraud Malsiner-Walli , Sylvia Frühwirth-Schnatter , Bettina Grün

Dirichlet process mixture models (DPMM) play a central role in Bayesian nonparametrics, with applications throughout statistics and machine learning. DPMMs are generally used in clustering problems where the number of clusters is not known…

Machine Learning · Statistics 2020-10-20 Chiao-Yu Yang , Eric Xia , Nhat Ho , Michael I. Jordan

DP-means clustering was obtained as an extension of $K$-means clustering. While it is implemented with a simple and efficient algorithm, it can estimate the number of clusters simultaneously. However, DP-means is specifically designed for…

Machine Learning · Computer Science 2021-08-26 Masahiro Kobayashi , Kazuho Watanabe