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Network motifs can capture basic interaction patterns and inform the functional properties of networks. However, real-world complex systems often have multiple types of relationships, which cannot be represented by a monolayer network. The…

Physics and Society · Physics 2019-03-06 Lu Zhong , Qingpeng Zhang , Dong Yang , Guanrong Chen , Shi Yu

Networks are fundamental for our understanding of complex systems. Interactions between individual nodes in networks generate network motifs - small recurrent patterns that can be considered the network's building-block components,…

Dynamical Systems · Mathematics 2022-09-14 Miri Adler , Ruslan Medzhitov

When studying a complex system it is often useful to think of the system as a network of interacting units. One can then ask if some properties of the entire network are already explained by a small part of the network - a network motif. A…

Populations and Evolution · Quantitative Biology 2025-09-03 Melanie Habermann , Ashkaan K. Fahimipour , Justin D. Yeakel , Thilo Gross

Network motifs are small building blocks of complex networks. Statistically significant motifs often perform network-specific functions. However, the precise nature of the connection between motifs and the global structure and function of…

Physics and Society · Physics 2015-03-03 Almerima Jamakovic , Priya Mahadevan , Amin Vahdat , Marian Boguna , Dmitri Krioukov

Network motifs are the building blocks of complex networks and are significantly involved in the network dynamics such as information processing and local operations in the brain, biological marks for drug targets, identifying and…

Physics and Society · Physics 2023-04-25 Bnaya Gross , Shlomo Havlin , Baruch Barzel

Complex networks evolve and vary their structure as time goes by. In particular, the links in those networks have both a sign and a directionality. To understand their structural principles, we measure the network motifs, which are patterns…

Physics and Society · Physics 2023-06-28 Youngjai Park , Mi Jin Lee , Seung-Woo Son

One of the most important concepts in biological network analysis is that of network motifs, which are patterns of interconnections that occur in a given network at a frequency higher than expected in a random network. In this work we are…

Discrete Mathematics · Computer Science 2020-05-29 Diego P Rubert , Eloi Araujo , Marco A Stefanes , Jens Stoye , Fábio V Martinez

Network science can offer fundamental insights into the structural and functional properties of complex systems. For example, it is widely known that neuronal circuits tend to organize into basic functional topological modules, called…

Adaptation and Self-Organizing Systems · Physics 2022-08-03 Matteo Zambra , Alberto Testolin , Amos Maritan

The study of motifs in networks can help researchers uncover links between the structure and function of networks in biology, sociology, economics, and many other areas. Empirical studies of networks have identified feedback loops,…

Physics and Society · Physics 2021-05-12 Alice C. Schwarze , Mason A. Porter

A determinant property of the structure of a biological network is the distribution of local connectivity patterns, i.e., network motifs. In this work, a method for creating directed, unweighted networks while promoting a certain…

Social and Information Networks · Computer Science 2016-07-29 Tuomo Mäki-Marttunen

Great part of the interest in complex networks has been motivated by the presence of structured, frequently non-uniform, connectivity. Because diverse connectivity patterns tend to result in distinct network dynamics, and also because they…

Disordered Systems and Neural Networks · Physics 2009-11-13 Paulino R. Villas Boas , Francisco A. Rodrigues , Gonzalo Travieso , Luciano da F. Costa

Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to…

Social and Information Networks · Computer Science 2018-01-08 Ashwin Paranjape , Austin R. Benson , Jure Leskovec

Many real-world networks describe systems in which interactions decay with the distance between nodes. Examples include systems constrained in real space such as transportation and communication networks, as well as systems constrained in…

Statistical Mechanics · Physics 2009-11-10 Shalev Itzkovitz , Uri Alon

Several natural and theoretical networks can be broken down into smaller portions, or subgraphs corresponding to neighborhoods. The more frequent of these neighborhoods can then be understood as motifs of the network, being therefore…

Physics and Society · Physics 2022-04-21 Guilherme S. Domingues , Eric K. Tokuda , Luciano da F. Costa

Studying the topology of so-called real networks, that is networks obtained from sociological or biological data for instance, has become a major field of interest in the last decade. One way to deal with it is to consider that networks are…

Applications · Statistics 2010-07-27 Etienne Birmele

Detecting strong ties among users in social and information networks is a fundamental operation that can improve performance on a multitude of personalization and ranking tasks. Strong-tie edges are often readily obtained from the social…

Social and Information Networks · Computer Science 2017-03-28 Rahmtin Rotabi , Krishna Kamath , Jon Kleinberg , Aneesh Sharma

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

Network motifs are often called the building blocks of networks. Analysis of motifs is found to be an indispensable tool for understanding local network structure, in contrast to measures based on node degree distribution and its functions…

Physics and Society · Physics 2017-08-23 Asim Kumer Dey , Yulia R. Gel , H. Vincent Poor

Complex network theory aims to model and analyze complex systems that consist of multiple and interdependent components. Among all studies on complex networks, topological structure analysis is of the most fundamental importance, as it…

Social and Information Networks · Computer Science 2010-09-15 Bo Yang , Jiming Liu

Many real-world phenomena are best represented as interaction networks with dynamic structures (e.g., transaction networks, social networks, traffic networks). Interaction networks capture flow of data which is transferred between their…

Social and Information Networks · Computer Science 2018-10-22 Chrysanthi Kosyfaki , Nikos Mamoulis , Evaggelia Pitoura , Panayiotis Tsaparas
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