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We show a data-driven approach to discover the underlying structural form of the mathematical equation governing the dynamics of multiple but similar systems induced by the same mechanisms. This approach hinges on theories that we lay out…

Neural and Evolutionary Computing · Computer Science 2019-08-29 Changwei Loh , Daniel Schneegass , Pengwei Tian

The characterization of network and biophysical properties from neural spiking activity is an important goal in neuroscience. A framework that provides unbiased inference on causal synaptic interaction and single neural properties has been…

Neurons and Cognition · Quantitative Biology 2024-05-27 Kevin S. Chen , Ying-Jen Yang

The problem of causal inference is to determine if a given probability distribution on observed variables is compatible with some causal structure. The difficult case is when the causal structure includes latent variables. We here introduce…

Quantum Physics · Physics 2019-07-24 Elie Wolfe , Robert W. Spekkens , Tobias Fritz

Learning the causal structure behind data is invaluable for improving generalization and obtaining high-quality explanations. We propose a novel framework, Invariant Structure Learning (ISL), that is designed to improve causal structure…

Machine Learning · Computer Science 2022-06-15 Yunhao Ge , Sercan Ö. Arik , Jinsung Yoon , Ao Xu , Laurent Itti , Tomas Pfister

Emergent behavior in complex systems arises from nonlinear interactions among components, yet the intricate nature of self-organization often obscures the underlying causal relationships, long regarded as the "holy grail" of complexity…

Adaptation and Self-Organizing Systems · Physics 2025-10-14 Lina Yan , Jeffrey Huy Khong , Aleksandar Kostadinov , Wen-Jun Chen , Jerry Ying Hsi Fuh , Chih-Ming Ho

Single- and multi-layer complex networks have been proven as a powerful tool to study the dynamics within social, technological,or natural systems. An often observed common goal there is to optimize these systems for specific purposes by…

Physics and Society · Physics 2021-02-11 Tanja Holstein , Marc Wiedermann , Jürgen Kurths

Efficient stochastic simulation algorithms are of paramount importance to the study of spreading phenomena on complex networks. Using insights and analytical results from network science, we discuss how the structure of contacts affects the…

Physics and Society · Physics 2019-07-24 Guillaume St-Onge , Jean-Gabriel Young , Laurent Hébert-Dufresne , Louis J. Dubé

Given observations of a physical system, identifying the underlying non-linear governing equation is a fundamental task, necessary both for gaining understanding and generating deterministic future predictions. Of most practical relevance…

Numerical Analysis · Mathematics 2020-03-02 A. Goeßmann , M. Götte , I. Roth , R. Sweke , G. Kutyniok , J. Eisert

Compressive sensing (CS) is a sampling technique designed for reducing the complexity of sparse data acquisition. One of the major obstacles for practical deployment of CS techniques is the signal reconstruction time and the high storage…

Information Theory · Computer Science 2011-07-12 Wei Dai , Olgica Milenkovic , Hoa Vin Pham

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

This Thesis explores how tools from Statistical Physics and Information Theory can help us describe and understand complex systems. In the first part, we study the interplay between internal interactions, environmental changes, and…

Statistical Mechanics · Physics 2023-03-01 Giorgio Nicoletti

We study pairwise Ising models for describing the statistics of multi-neuron spike trains, using data from a simulated cortical network. We explore efficient ways of finding the optimal couplings in these models and examine their…

Quantitative Methods · Quantitative Biology 2009-05-21 Yasser Roudi , Joanna Tyrcha , John Hertz

Correlation matrices are a major type of multivariate data. To examine properties of a given correlation matrix, a common practice is to compare the same quantity between the original correlation matrix and reference correlation matrices,…

Physics and Society · Physics 2018-07-25 Naoki Masuda , Sadamori Kojaku , Yukie Sano

This letter seeks to illuminate the profound connection between complexity, self-organization, emergent behaviour, pattern formation, and entropy concepts that are foundational to understanding our universe. By examining these ideas through…

Adaptation and Self-Organizing Systems · Physics 2025-03-25 Vinesh Vijayan , Karpagavalli K , Sandhiya Jenifer J , Prakash R

A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for…

Data collection and research methodology represents a critical part of the research pipeline. On the one hand, it is important that we collect data in a way that maximises the validity of what we are measuring, which may involve the use of…

Methodology · Statistics 2022-04-20 Matthew J. Vowels

For biological experiments aiming at calibrating models with unknown parameters, a good experimental design is crucial, especially for those subject to various constraints, such as financial limitations, time consumption and physical…

Applications · Statistics 2014-07-22 Xiao Lin , Gabriel Terejanu

Learning the dynamic causal structure of time series is a challenging problem. Most existing approaches rely on distributional or structural invariance to uncover underlying causal dynamics, assuming stationary or partially stationary…

Machine Learning · Computer Science 2026-02-27 Dezhi Yang , Qiaoyu Tan , Carlotta Domeniconi , Jun Wang , Lizhen Cui , Guoxian Yu

Optimisation problems in science and engineering typically involve finding the ground state (i.e. the minimum energy configuration) of a cost function with respect to many variables. If the variables are corrupted by noise then this…

Quantum Physics · Physics 2016-03-08 Nicholas Chancellor , Szilard Szoke , Walter Vinci , Gabriel Aeppli , Paul A. Warburton

Real world systems evolve in continuous-time according to their underlying causal relationships, yet their dynamics are often unknown. Existing approaches to learning such dynamics typically either discretize time -- leading to poor…

Machine Learning · Computer Science 2025-12-17 Nicholas Tagliapietra , Katharina Ensinger , Christoph Zimmer , Osman Mian