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When generating in-silico clinical electrophysiological outputs, such as electrocardiograms (ECGs) and body surface potential maps (BSPMs), mathematical models have relied on single physics, i.e. of the cardiac electrophysiology (EP),…

Numerical Analysis · Mathematics 2024-02-12 Elena Zappon , Matteo Salvador , Roberto Piersanti , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

A lot of work on clamped circular, square and rectangular shaped capacitive pressure sensor has been carried out. However, to the best of our knowledge, no elaborate work has been performed on mathematical formulation and simulation of…

Applied Physics · Physics 2019-10-02 Rishabh Bhooshan Mishra , S. Santosh Kumar

Autonomic nervous system is important for cardiac function regulation. Modeling of autonomic cardiac regulation can contribute to health tracking and disease management. This study proposed a mathematical model that simulates autonomic…

Medical Physics · Physics 2024-08-28 Runwei Lin , Frank Halfwerk , Dirk Donker , Gozewijn Dirk Laverman , Ying Wang

Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to…

Tissues and Organs · Quantitative Biology 2018-07-04 Laura Ellwein Fix , Joseph Khoury , Russell Moores , Lauren Linkous , Matthew Brandes , Henry J. Rozycki

We report three-dimensional and time-dependent numerical simulations of the propagation of electrical action potentials in a model of rabbit ventricular tissue. The simulations are performed using a finite-element method for the solution of…

Quantitative Methods · Quantitative Biology 2021-05-20 Peter Mortensen , Muhamad H. N. Aziz , Hao Gao , Radostin D. Simitev

The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in space and frictionless sliding of the myocardium.…

Computational Engineering, Finance, and Science · Computer Science 2018-12-11 Martin R. Pfaller , Julia M. Hörmann , Martina Weigl , Andreas Nagler , Radomir Chabiniok , Cristóbal Bertoglio , Wolfgang A. Wall

We present a technique designed for parallelizing large rigid body simulations, capable of exploiting multiple CPU cores within a computer and across a network. Our approach can be applied to simulate both unilateral and bilateral…

Graphics · Computer Science 2024-03-27 Manas Kale , Paul G. Kry

Predicting cardiac indices has long been a focal point in the medical imaging community. While various deep learning models have demonstrated success in quantifying cardiac indices, they remain susceptible to mild input perturbations, e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Xiangyang Zhu , Kede Ma , Wufeng Xue

Motivated by existing models used for soft body simulation which are rather complex to implement, we present a novel technique which is based on simple laws of physics and gives high quality results in real-time. We base the implementation…

Computational Physics · Physics 2007-05-23 Matyka Maciej , Ollila Mark

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée

This paper presents a novel particle method to compute strongly coupled incompressible fluid and rigid bodies. The method adopts a velocity-based formulation and utilizes the linear complementarity problem for the incompressibility…

Fluid Dynamics · Physics 2023-03-01 Shugo Miyamoto , Seiichi Koshizuka

Predictive high-fidelity finite element simulations of human cardiac mechanics co\-mmon\-ly require a large number of structural degrees of freedom. Additionally, these models are often coupled with lumped-parameter models of hemodynamics.…

Computational Engineering, Finance, and Science · Computer Science 2020-02-18 Martin R. Pfaller , Maria Cruz Varona , Johannes Lang , Cristóbal Bertoglio , Wolfgang A. Wall

Ewald summation and physically equivalent methods such as particle-mesh Ewald, kubic-harmonic expansions, or Lekner sums are commonly used to calculate long-range electrostatic interactions in computer simulations of polar and charged…

Chemical Physics · Physics 2009-10-31 Gerhard Hummer , Niels Grønbech-Jensen , Martin Neumann

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

Electrical impedance tomography is an imaging modality for extracting information on the interior structure of a physical body from boundary measurements of current and voltage. This work studies a new robust way of modeling the contact…

Numerical Analysis · Mathematics 2022-07-06 J. Dardé , N. Hyvönen , T. Kuutela , T. Valkonen

The creation of unique control methods for a hand prosthesis is still a problem that has to be addressed. The best choice of a human-machine interface (HMI) that should be used to enable natural control is still a challenge. Surface…

In a previous publication we demonstrated that the stable and unstable equilibrium states of prismatic Coulomb actuated Euler-Bernoulli micro-beams, clamped at both ends, can successfully be simulated combining finite element analysis (FEM)…

We present a novel mathematical model that simulates myocardial blood perfusion by embedding multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, reduced valve…

Computational Engineering, Finance, and Science · Computer Science 2023-03-27 Alberto Zingaro , Christian Vergara , Luca Dede' , Francesco Regazzoni , Alfio Quarteroni

Computer simulation of "virtual interventions" may inform optimal valve repair for a given patient prior to intervention. However, the paucity of noninvasive methods to determine in vivo mechanical parameters of valves limits the accuracy…

Quantitative Methods · Quantitative Biology 2025-07-09 Wensi Wu , Mitchell Daneker , Christian Herz , Hannah Dewey , Jeffrey A. Weiss , Alison M. Pouch , Lu Lu , Matthew A. Jolley

Fluid flow simulation is a highly active area with applications in a wide range of engineering problems and interactive systems. Meshless methods like the Moving Particle Semi-implicit (MPS) are a great alternative to deal efficiently with…

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