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Understanding how brain networks learn and manage multiple tasks simultaneously is of interest in both neuroscience and artificial intelligence. In this regard, a recent research thread in theoretical neuroscience has focused on how…

Neurons and Cognition · Quantitative Biology 2024-08-05 Giacomo Vedovati , ShiNung Ching

A core challenge for the brain is to process information across various timescales. This could be achieved by a hierarchical organization of temporal processing through intrinsic mechanisms (e.g., recurrent coupling or adaptation), but…

Neurons and Cognition · Quantitative Biology 2024-01-18 Lucas Rudelt , Daniel González Marx , F. Paul Spitzner , Benjamin Cramer , Johannes Zierenberg , Viola Priesemann

We apply Dynamic Causal Models to electrocorticogram recordings from two macaque monkeys performing a problem-solving task that engages working memory, and induces time-on-task effects. We thus provide a computational account of changes in…

Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Since the earliest electroencephalography experiments, large scale oscillations have been observed in the mammalian brain. More recently, episodes of oscillation and bursting have been identified not only in the cerebral cortex and…

Neurons and Cognition · Quantitative Biology 2025-09-03 Daniel Pouzzner

We address the problem of identifying functional interactions among stochastic neurons with variable-length memory from their spiking activity. The neuronal network is modeled by a stochastic system of interacting point processes with…

Applications · Statistics 2025-07-01 Ricardo F. Ferreira , Matheus E. Pacola , Vitor G. Schiavone , Rodrigo F. O. Pena

We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

Biological Physics · Physics 2007-05-23 S. Panzeri , S. R. Schultz

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

Biological Physics · Physics 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall

In this paper, we consider networks of deterministic spiking neurons, firing synchronously at discrete times; such spiking neural networks are inspired by networks of neurons and synapses that occur in brains. We consider the problem of…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-17 Nancy Lynch , Mien Brabeeba Wang

We describe a new, computationally simple method for analyzing the dynamics of neuronal spike trains driven by external stimuli. The goal of our method is to test the predictions of simple spike-generating models against extracellularly…

Neurons and Cognition · Quantitative Biology 2007-05-23 Daniel S. Reich , Jonathan D. Victor , Bruce W. Knight

Correlations in spike-train ensembles can seriously impair the encoding of information by their spatio-temporal structure. An inevitable source of correlation in finite neural networks is common presynaptic input to pairs of neurons. Recent…

Neurons and Cognition · Quantitative Biology 2015-06-04 Tom Tetzlaff , Moritz Helias , Gaute T. Einevoll , Markus Diesmann

Neural coding is a field of study that concerns how sensory information is represented in the brain by networks of neurons. The link between external stimulus and neural response can be studied from two parallel points of view. The first,…

Neurons and Cognition · Quantitative Biology 2012-03-07 Shinsuke Koyama

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

Neurons and Cognition · Quantitative Biology 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

Conventionally, information is represented by spike rates in the neural system. Here, we consider the ability of temporally modulated activities in neuronal networks to carry information extra to spike rates. These temporal modulations,…

Neurons and Cognition · Quantitative Biology 2014-09-09 C. C. Alan Fung , He Wang , Kin Lam , K. Y. Michael Wong , Si Wu

This paper addresses two main challenges facing systems neuroscience today: understanding the nature and function of a) cortical feedback between sensory areas and b) correlated variability. Starting from the old idea of perception as…

Neurons and Cognition · Quantitative Biology 2015-11-20 Ralf M. Haefner , Pietro Berkes , József Fiser

Cortical neurons include many sub-cellular processes, operating at multiple timescales, which may affect their response to stimulation through non-linear and stochastic interaction with ion channels and ionic concentrations. Since new…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

One of the main current issues in Neurobiology concerns the understanding of interrelated spiking activity among multineuronal ensembles and differences between stimulus-driven and spontaneous activity in neurophysiological experiments.…

Neurons and Cognition · Quantitative Biology 2017-10-13 Ludmila Brochini , Antonio Galves , Pierre Hodara , Guilherme Ost , Christophe Pouzat

We apply an information theoretic treatment of action potential time series measured with microelectrode arrays to estimate the connectivity of mammalian neuronal cell assemblies grown {\it in vitro}. We infer connectivity between two…

Neurons and Cognition · Quantitative Biology 2007-05-23 Luis M. A. Bettencourt , Greg J. Stephens , Michael I. Ham , Guenter W. Gross

The cortical processes involved in learning are not well understood. Recent experiments have studied population-level response in the orofacial somatosensory (S1) and motor (S1) cortices of rhesus macaque monkeys during adaptation to a…

Neurons and Cognition · Quantitative Biology 2014-05-26 Alexander Conway , Fritzie Arce

In daily life situations, we have to perform multiple tasks given a visual stimulus, which requires task-relevant information to be transmitted through our visual system. When it is not possible to transmit all the possibly relevant…

Neurons and Cognition · Quantitative Biology 2019-09-24 Sushrut Thorat , Giacomo Aldegheri , Marcel A. J. van Gerven , Marius V. Peelen