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We propose a reinforcement-learning algorithm to tackle the challenge of reconstructing phylogenetic trees. The search for the tree that best describes the data is algorithmically challenging, thus all current algorithms for phylogeny…

Populations and Evolution · Quantitative Biology 2023-03-14 Dana Azouri , Oz Granit , Michael Alburquerque , Yishay Mansour , Tal Pupko , Itay Mayrose

We consider stochastic approximation with block-coordinate stepsizes and propose adaptive stepsize rules that aim to minimize the expected distance from the next iterate to an (unknown) target point. These stepsize rules employ online…

Optimization and Control · Mathematics 2025-12-09 Tao Jiang , Lin Xiao

There has been a lot of recent work on Bayesian methods for reinforcement learning exhibiting near-optimal online performance. The main obstacle facing such methods is that in most problems of interest, the optimal solution involves…

Machine Learning · Computer Science 2009-12-31 Christos Dimitrakakis

We consider the problem of learning the structure of undirected graphical models with bounded treewidth, within the maximum likelihood framework. This is an NP-hard problem and most approaches consider local search techniques. In this…

Machine Learning · Computer Science 2012-12-12 K. S. Sesh Kumar , Francis Bach

Random forests are a statistical learning technique that use bootstrap aggregation to average high-variance and low-bias trees. Improvements to random forests, such as applying Lasso regression to the tree predictions, have been proposed in…

Machine Learning · Statistics 2025-11-13 Jing Shang , James Bannon , Benjamin Haibe-Kains , Robert Tibshirani

Data reconstruction attacks on trained neural networks aim to recover the data on which the network has been trained and pose a significant threat to privacy, especially if the training dataset contains sensitive information. Here, we…

Machine Learning · Computer Science 2026-05-08 Edward Tansley , Roy Makhlouf , Estelle Massart , Coralia Cartis

Connected acyclic graphs (trees) are data objects that hierarchically organize categories. Collections of trees arise in a diverse variety of fields, including evolutionary biology, public health, machine learning, social sciences and…

Methodology · Statistics 2025-12-01 Maria Alejandra Valdez Cabrera , Amy D Willis , Armeen Taeb

Ancestral state reconstruction is one of the most important tasks in evolutionary biology. Conditions under which we can reliably reconstruct the ancestral state have been studied for both discrete and continuous traits. However, the…

Populations and Evolution · Quantitative Biology 2021-11-16 Lam Si Tung Ho , Vu Dinh

Methods for reconstructing the topology of complex networks from time-resolved observations of node dynamics are gaining relevance across scientific disciplines. Of biggest practical interest are methods that make no assumptions about…

We show that the problem of constructing tree-structured descriptions of data layouts that are optimal with respect to space or other criteria from given sequences of displacements, can be solved in polynomial time. The problem is relevant…

Data Structures and Algorithms · Computer Science 2015-07-01 Robert Ganian , Martin Kalany , Stefan Szeider , Jesper Larsson Träff

The number of algorithms available to reconstruct a biological network from a dataset of high-throughput measurements is nowadays overwhelming, but evaluating their performance when the gold standard is unknown is a difficult task. Here we…

Molecular Networks · Quantitative Biology 2012-09-11 Giuseppe Jurman , Michele Filosi , Roberto Visintainer , Samantha Riccadonna , Cesare Furlanello

Research into the classification of time series has made enormous progress in the last decade. The UCR time series archive has played a significant role in challenging and guiding the development of new learners for time series…

Random forests are considered one of the best out-of-the-box classification and regression algorithms due to their high level of predictive performance with relatively little tuning. Pairwise proximities can be computed from a trained…

Machine Learning · Statistics 2023-03-02 Jake S. Rhodes , Adele Cutler , Kevin R. Moon

Geodesic distance, sometimes called shortest path length, has proven useful in a great variety of applications, such as information retrieval on networks including treelike networked models. Here, our goal is to analytically determine the…

Combinatorics · Mathematics 2020-10-29 Fei Ma , Ping Wang , Xudong Luo

Balanced minimum evolution (BME) is a statistically consistent distance-based method to reconstruct a phylogenetic tree from an alignment of molecular data. In 2000, Pauplin showed that the BME method is equivalent to optimizing a linear…

Populations and Evolution · Quantitative Biology 2015-03-14 David C. Haws , Terrell Hodge , Ruriko Yoshida

An increasing array of biomedical and computer vision applications requires the predictive modeling of complex data, for example images and shapes. The main challenge when predicting such objects lies in the fact that they do not comply to…

Machine Learning · Statistics 2017-02-17 Dimosthenis Tsagkrasoulis , Giovanni Montana

Dual-tree algorithms are a widely used class of branch-and-bound algorithms. Unfortunately, developing dual-tree algorithms for use with different trees and problems is often complex and burdensome. We introduce a four-part logical split:…

Data Structures and Algorithms · Computer Science 2013-04-17 Ryan R. Curtin , William B. March , Parikshit Ram , David V. Anderson , Alexander G. Gray , Charles L. Isbell

Man-made environments typically comprise planar structures that exhibit numerous geometric relationships, such as parallelism, coplanarity, and orthogonality. Making full use of these relationships can considerably improve the robustness of…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Yangbin Lin , Jialian Li , Cheng Wang , Zhonggui Chen , Zongyue Wang , Jonathan Li

We study the problem of approximating a discrete probability distribution, such as the next-token distribution of a large language model, by a dyadic distribution induced by a binary tree under encoding rate constraints. The objective is to…

Information Theory · Computer Science 2026-05-08 Daniella Bar-Lev , Farzad Farnoud , Ryan Gabrys

In this paper, we lay the groundwork on the comparison of phylogenetic networks based on edge contractions and expansions as edit operations, as originally proposed by Robinson and Foulds to compare trees. We prove that these operations…

Data Structures and Algorithms · Computer Science 2025-02-21 Bertrand Marchand , Nadia Tahiri , Olivier Tremblay-Savard , Manuel Lafond