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A distance-based method to reconstruct a phylogenetic tree with $n$ leaves takes a distance matrix, $n \times n$ symmetric matrix with $0$s in the diagonal, as its input and reconstructs a tree with $n$ leaves using tools in combinatorics.…

Populations and Evolution · Quantitative Biology 2015-08-03 Jing Xi , Jin Xie , Ruriko Yoshida , Stefan Forcey

Recent theoretical work has demonstrated that Neighbor Joining applied to concatenated DNA sequences is a statistically consistent method of species tree reconstruction. This brief note compares the accuracy of this approach to other…

Populations and Evolution · Quantitative Biology 2016-12-07 Joseph Rusinko , Matthew McPartlon

The Neighbor-Joining algorithm is a recursive procedure for reconstructing trees that is based on a transformation of pairwise distances between leaves. We present a generalization of the neighbor-joining transformation, which uses…

Quantitative Methods · Quantitative Biology 2007-05-23 Dan Levy , Ruriko Yoshida , Lior Pachter

Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences from them construct a value that, in expectation, is additive under a stochastic…

Populations and Evolution · Quantitative Biology 2008-08-21 Mike Steel

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

Populations and Evolution · Quantitative Biology 2009-09-30 Frederick A. Matsen

The Neighbor-Joining algorithm is a popular distance-based phylogenetic method that computes a tree metric from a dissimilarity map arising from biological data. Realizing dissimilarity maps as points in Euclidean space, the algorithm…

Combinatorics · Mathematics 2020-09-18 Ruth Davidson , Abraham Martin del Campo

We show that the neighbor-joining algorithm is a robust quartet method for constructing trees from distances. This leads to a new performance guarantee that contains Atteson's optimal radius bound as a special case and explains many cases…

Data Structures and Algorithms · Computer Science 2007-06-17 Radu Mihaescu , Dan Levy , Lior Pachter

Due to hybridization events in evolution, studying two different genes of a set of species may yield two related but different phylogenetic trees for the set of species. In this case, we want to measure the dissimilarity of the two trees.…

Data Structures and Algorithms · Computer Science 2017-07-28 Zhi-Zhong Chen , Eita Machida , Lusheng Wang

Supertree methods are tree reconstruction techniques that combine several smaller gene trees (possibly on different sets of species) to build a larger species tree. The question of interest is whether the reconstructed supertree converges…

Populations and Evolution · Quantitative Biology 2021-05-06 Lam Si Tung Ho , Vu Dinh

A common assumption in multiple scientific applications is that the distribution of observed data can be modeled by a latent tree graphical model. An important example is phylogenetics, where the tree models the evolutionary lineages of a…

Machine Learning · Statistics 2020-09-24 Ariel Jaffe , Noah Amsel , Yariv Aizenbud , Boaz Nadler , Joseph T. Chang , Yuval Kluger

In many interesting cases the reconstruction of a correct phylogeny is blurred by high mutation rates and/or horizontal transfer events. As a consequence a divergence arises between the true evolutionary distances and the differences…

Populations and Evolution · Quantitative Biology 2010-02-08 F. Tria , E. Caglioti , V. Loreto , A. Pagnani

Among the distance based algorithms in phylogenetic tree reconstruction, the neighbor-joining algorithm has been a widely used and effective method. We propose a new algorithm which counts the number of consistent quartets for cherry…

Populations and Evolution · Quantitative Biology 2023-10-31 Jin-Hwan Cho , Dosang Joe , Young Rock Kim

The widely used model for evolutionary relationships is a bifurcating tree with all taxa/observations placed at the leaves. This is not appropriate if the taxa have been densely sampled across evolutionary time and may be in a direct…

Populations and Evolution · Quantitative Biology 2017-01-12 Prabhav Kalaghatgi , Nico Pfeifer , Thomas Lengauer

In this work we study the interleaving distance between merge trees from a combinatorial point of view. We use a particular type of matching between trees to obtain a novel formulation of the distance. With such formulation, we tackle the…

Combinatorics · Mathematics 2024-11-11 Matteo Pegoraro

Stochastic versions of proximal methods have gained much attention in statistics and machine learning. These algorithms tend to admit simple, scalable forms, and enjoy numerical stability via implicit updates. In this work, we propose and…

Machine Learning · Statistics 2024-09-09 Haoyu Jiang , Jason Xu

The popular neighbor-joining (NJ) algorithm used in phylogenetics is a greedy algorithm for finding the balanced minimum evolution (BME) tree associated to a dissimilarity map. From this point of view, NJ is ``optimal'' when the algorithm…

Quantitative Methods · Quantitative Biology 2007-10-29 Kord Eickmeyer , Peter Huggins , Lior Pachter , Ruriko Yoshida

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

Populations and Evolution · Quantitative Biology 2013-07-24 Ruth Davidson , Seth Sullivant

Rotation distance between rooted binary trees measures the number of simple operations it takes to transform one tree into another. There are no known polynomial-time algorithms for computing rotation distance. We give an efficient,…

Data Structures and Algorithms · Computer Science 2018-03-19 Sean Cleary , Katherine St. John

The study of Markov processes and broadcasting on trees has deep connections to a variety of areas including statistical physics, graphical models, phylogenetic reconstruction, Markov Chain Monte Carlo, and community detection in random…

Probability · Mathematics 2022-10-26 Frederic Koehler , Elchanan Mossel

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski
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