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We report current blockade (CB) characteristics of molecular motifs residing on a model dsDNA using electrokinetic Brownian dynamics (EKBD) and study the role of the valence of the counterions as the dsDNA translocates through a solitary…

Soft Condensed Matter · Physics 2023-08-29 Swarnadeep Seth , Aniket Bhattacharya

Genome editing allows scientists to change an organism's DNA. One promising genome editing protocol, already validated in living organisms, is based on clustered regularly interspaced short palindromic repeats (CRISPR)/Cas protein-nucleic…

Biological Physics · Physics 2019-07-25 Angana Ray , Rosa Di Felice

The transport of bio-particles in viscous flows exhibits a rich variety of dynamical behaviour, such as morphological transitions, complex orientation dynamics or deformations. Characterising such complex behaviour under well controlled…

We explore nanoribbons from topological two-dimensional stanene as channel material in tunnel field effect transistors. This novel technological option offers the possibility to build pure one-dimensional (1D) channel devices (comprised of…

Mesoscale and Nanoscale Physics · Physics 2018-04-11 Enrique G. Marin , Damiano Marian , Giuseppe Iannaccone , Gianluca Fiori

Portable genome sequencing technology is revolutionizing genomic research by providing a faster, more flexible method of sequencing DNA and RNA [1, 2]. The unprecedented shift from bulky stand-alone benchtop equipment confined in a…

Cryptography and Security · Computer Science 2024-07-18 Carson Stillman , Jonathan E. Bravo , Christina Boucher , Sara Rampazzi

The fluidic behavior of water at the micro/nano scale is studied by using of single DNA molecules as a model system. Stable curved DNA patterns with spans about one micron were generated by using of water flows, and observed by Atomic Force…

Biological Physics · Physics 2007-05-23 Yi Zhang , Huabing Li , Xiaoling Lei , Junhong Lv , Xiaobai Ai , Hu Jun , Shiyi Chen , Fang Haiping

Exploiting physical processes for fast and energy-efficient computation bears great potential in the advancement of modern hardware components. This paper explores non-linear charge tunneling in nanoparticle networks, controlled by external…

Computational Physics · Physics 2024-02-20 Evan Wonisch , Jonas Mensing , Andreas Heuer

Detection of nano-mechanical displacement by transport techniques has reached high level of sensitivity and versatility. In order to detect the amplitude of oscillation of nano-mechanical oscillator a widely used technique consists to…

Mesoscale and Nanoscale Physics · Physics 2017-01-18 Yue Wang , Fabio Pistolesi

Electron transmission through molecules and molecular interfaces has been a subject of intensive research due to recent interest in electron transfer phenomena underlying the operation of the scanning tunneling microscope (STM) on one hand,…

Condensed Matter · Physics 2015-06-24 Abraham Nitzan

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

With the progressive scale-down of semiconductor's feature size, people are looking forward to More Moore and More than Moore. In order to offer a possible alternative implementation process, people are trying to figure out a feasible…

Emerging Technologies · Computer Science 2018-07-06 Chuan Zhang , Lulu Ge , Yuchen Zhuang , Ziyuan Shen , Zhiwei Zhong , Zaichen Zhang , Xiaohu You

Miniature DNA sequencing hardware has begun to succeed in mobile contexts, driving demand for efficient machine learning at the edge. This domain leverages deep learning techniques familiar from speech and time-series analysis for both…

Hardware Architecture · Computer Science 2025-10-13 Sebastian Magierowski , Zhongpan Wu , Abel Beyene , Karim Hammad

So far transport properties of nanoscale contacts have been mostly studied within the static scattering approach. The electron dynamics and the transient behavior of current flow, however, remain poorly understood. We present a numerical…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Na Sai , Neil Bushong , Ryan Hatcher , Massimiliano Di Ventra

Angstrom-scale fluidic channels are ubiquitous in nature, and play an important role in regulating cellular traffic, signaling, and responding to stimuli. Synthetic channels are now a reality with the emergence of several cutting-edge…

Mesoscale and Nanoscale Physics · Physics 2022-12-20 Yi You , Abdulghani Ismail , Gwang-Hyeon Nam , Solleti Goutham , Ashok Keerthi , Boya Radha

Quantum tunnelling of electrons can be confined to the sub-cycle time scale of strong light fields, contributing decisively to the extreme time resolution of attosecond science. Because tunnelling also enables atomic-scale spatial…

The threading of a polymer chain through a small pore is a classic problem in polymer dynamics and underlies nanopore sensing technology. However important experimental aspects of the polymer motion in a solid-state nanopore, such as an…

Biological Physics · Physics 2016-07-18 Nicholas A. W. Bell , Ulrich F. Keyser

We examine the behavior of a model which describes the melting of double-stranded DNA chains. The model, with displacement-dependent stiffness constants and a Morse on-site potential, is analyzed numerically; depending on the stiffness…

Statistical Mechanics · Physics 2009-10-31 Nikos Theodorakopoulos , Thierry Dauxois , Michel Peyrard

Inspired by its central role in many biological processes, the transport of biopolymers across nanoscale pores is at the heart of a single-molecule sensing technology aimed at nucleic acid and protein sequencing, as well as biomarker…

Biological Physics · Physics 2025-10-16 Martin Charron , Breeana Elliott , Nada Kerrouri , Liqun He , Vincent Tabard-Cossa

We inspect signatures of dynamical quantum phase transitions driven by two types of quenches acting on a correlated quantum dot embedded between superconducting and metallic reservoirs. Under stationary conditions the proximity induced…

Mesoscale and Nanoscale Physics · Physics 2022-03-29 Kacper Wrześniewski , Ireneusz Weymann , Nicholas Sedlmayr , Tadeusz Domański

DNA storage is now being considered as a new archival storage method for its durability and high information density, but still facing some challenges like high costs and low throughput. By reducing sequencing sample size for decoding…

Information Theory · Computer Science 2025-04-22 Ruiying Cao , Xin Chen