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Given a collection of features available for inclusion in a predictive model, it may be of interest to quantify the relative importance of a subset of features for the prediction task at hand. For example, in HIV vaccine trials, participant…

Methodology · Statistics 2025-03-27 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Inference for causal effects can benefit from the availability of an instrumental variable (IV) which, by definition, is associated with the given exposure, but not with the outcome of interest other than through a causal exposure effect.…

Methodology · Statistics 2012-01-13 Stijn Vansteelandt , Jack Bowden , Manoochehr Babanezhad , Els Goetghebeur

Mendelian randomization (MR) is a popular method in genetic epidemiology to estimate the effect of an exposure on an outcome by using genetic instruments. These instruments are often selected from a combination of prior knowledge from…

Methodology · Statistics 2019-11-12 Nan Bi , Hyunseung Kang , Jonathan Taylor

Civil registration vital statistics (CRVS) data are used to produce national estimates of maternal mortality, but are often subject to substantial reporting errors due to misclassification of maternal deaths. The accuracy of CRVS systems…

Applications · Statistics 2019-09-19 Emily Peterson , Doris Chou , Ann-Beth Moller , Alison Gemmill , Lale Say , Leontine Alkema

Mendelian randomization (MR) considers using genetic variants as instrumental variables (IVs) to infer causal effects in observational studies. However, the validity of causal inference in MR can be compromised when the IVs are potentially…

Methodology · Statistics 2024-02-06 Ziya Xu , Sai Li

In the field of road safety, it is common to use responsibility analyses to assess the effect of a given factor on the risk of being responsible for an accident, among drivers involved in an accident only. Even if this design is now widely…

Methodology · Statistics 2018-10-16 Marine Dufournet , Emilie Lanoy , Jean-Louis Martin , Vivian Viallon

This paper considers the problem of forecasting mortality rates. A large number of models have already been proposed for this task, but they generally have the disadvantage of either estimating the model in a two-step process, possibly…

Applications · Statistics 2023-05-26 Patrik Andersson , Mathias Lindholm

Road fatalities pose significant public safety and health challenges worldwide, with pedestrians being particularly vulnerable in vehicle-pedestrian crashes due to disparities in physical and performance characteristics. This study employs…

Machine Learning · Computer Science 2025-03-25 Methusela Sulle , Judith Mwakalonge , Gurcan Comert , Saidi Siuhi , Nana Kankam Gyimah

Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounders. However, the availability of instrumental variables in the primary dataset is often challenged due to stringent…

Methodology · Statistics 2026-03-31 Kang Shuai , Shanshan Luo , Wei Li , Yangbo He

Theoretically as well as experimentally it is investigated how people represent their knowledge in order to make decisions or to share their knowledge with others. Experiment 1 probes into the ways how people 6ather information about the…

Artificial Intelligence · Computer Science 2013-04-15 Alf C. Zimmer

Background: The predictive Intensive Care Unit (ICU) scoring system plays an important role in ICU management because it predicts important outcomes, especially mortality. Many scoring systems have been developed and used in the ICU. These…

Artificial Intelligence · Computer Science 2023-07-18 Mingquan Lin , Song Wang , Ying Ding , Lihui Zhao , Fei Wang , Yifan Peng

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the…

There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

Applications · Statistics 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

To answer questions of "causes of effects", the probability of necessity is introduced for assessing whether or not an observed outcome was caused by an earlier treatment. However, the statistical inference for probability of necessity is…

Methodology · Statistics 2025-04-14 Ping Zhang , Ruoyu Wang , Wang Miao

Analyzing large datasets and summarizing it into useful information is the heart of the data mining process. In healthcare, information can be converted into knowledge about patient historical patterns and possible future trends. During the…

Machine Learning · Computer Science 2024-12-02 Dheeman Saha , Aaron Segura , Biraj Tiwari

Instrumental variable methods are widely used for inferring the causal effect in the presence of unmeasured confounders. Existing instrumental variable methods for nonlinear outcome models require stringent identifiability conditions. This…

Methodology · Statistics 2022-07-01 Sai Li , Zijian Guo

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

Understanding causal explanations - reasons given for happenings in one's life - has been found to be an important psychological factor linked to physical and mental health. Causal explanations are often studied through manual…

Computation and Language · Computer Science 2018-10-19 Youngseo Son , Nipun Bayas , H. Andrew Schwartz

The analysis of causal effects when the outcome of interest is possibly truncated by death has a long history in statistics and causal inference. The survivor average causal effect is commonly identified with more assumptions than those…

Methodology · Statistics 2020-03-24 Jaffer M. Zaidi , Eric J. Tchetgen Tchetgen , Tyler J. VanderWeele

Separate modelling of cause specific mortality rates and their projections can yield inconsistent forecasts when the sum of deaths by cause does not match the total observed in a population. We develop a hierarchical probabilistic framework…

Applications · Statistics 2026-03-03 Andrea Nigri , Han Lin Shang , Francesco Ungolo