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Parameter sensitivity analysis is a powerful tool in the building and analysis of biochemical network models. For stochastic simulations, parameter sensitivity analysis can be computationally expensive, requiring multiple simulations for…

Computational Physics · Physics 2015-06-04 Patrick B. Warren , Rosalind J. Allen

Recently, distributed algorithms for power system state estimation have attracted significant attention. Along with such advantages as decomposition, parallelization of the original problem and absence of a central computation unit,…

Optimization and Control · Mathematics 2020-07-07 Samal Kubentayeva , Elena Gryazina , Sergei Parsegov , Alexander Gasnikov , Federico Ibáñez

We propose a new estimation method for the Stable Trait, Auto Regressive Trait, and State (STARTS) model, which is well known for its frequent occurrence of improper solutions. The proposed approach is implemented through a two-stage…

Methodology · Statistics 2026-01-06 Satoshi Usami

Thermodynamic phase transitions, a central concept in physics and chemistry, are typically controlled by an interplay of enthalpic and entropic contributions. In most cases, the estimation of the enthalpy in simulations is straightforward…

Soft Condensed Matter · Physics 2025-10-30 Yamin Ben-Shimon , Barak Hirshberg , Yohai Bar-Sinai

The statistics of the diffusive motion of particles often serve as an experimental proxy for their interaction with the environment. However, inferring the physical properties from the observed trajectories is challenging. Inspired by a…

Soft Condensed Matter · Physics 2024-05-29 Amit Federbush , Amit Moscovich , Yohai Bar-Sinai

Power electronic devices such as HVDC and FACTS can be used to improve the damping of poorly damped inter-area modes in large power systems. This involves the use of wide-area feedback signals, which are transmitted via communication…

Systems and Control · Electrical Eng. & Systems 2022-11-17 K. K. Gajjar , Kaustav Dey , A. M. Kulkarni

The increasing deployment of distribution-level phasor measurement units (PMUs) calls for dynamic distribution state estimation (DDSE) approaches that tap into high-rate measurements to maintain a comprehensive view of the…

Optimization and Control · Mathematics 2020-01-09 Jianhan Song , Emiliano Dall'Anese , Andrea Simonetto , Hao Zhu

Many state of the art methods for the thermodynamic and kinetic characterization of large and complex biomolecular systems by simulation rely on ensemble approaches, where data from large numbers of relatively short trajectories are…

Data Analysis, Statistics and Probability · Physics 2017-04-05 Feliks Nüske , Hao Wu , Jan-Hendrik Prinz , Christoph Wehmeyer , Cecilia Clementi , Frank Noé

We show how thermodynamic properties of molecular models can be computed over a large, multidimensional parameter space by combining multistate reweighting analysis with a linear basis function approach. This approach reduces the…

Chemical Physics · Physics 2016-05-18 Levi N. Naden , Michael R. Shirts

The minimum action method (MAM) is to calculate the most probable transition path in randomly perturbed stochastic dynamics, based on the idea of action minimization in the path space. The accuracy of the numerical path between different…

Computational Physics · Physics 2017-05-26 Y Sun , X Zhou

To control a dynamical system it is essential to obtain an accurate estimate of the current system state based on uncertain sensor measurements and existing system knowledge. An optimization-based moving horizon estimation (MHE) approach…

Systems and Control · Electrical Eng. & Systems 2022-05-03 Simon Muntwiler , Kim P. Wabersich , Melanie N. Zeilinger

A scheme is developed for estimating state-dependent drift and diffusion coefficients in a stochastic differential equation from time-series data. The scheme does not require to specify parametric forms for the drift and diffusion…

Biological Physics · Physics 2012-09-28 Jun Ohkubo

The statistical-thermodynamic dislocation theory developed in previous papers is used here in an analysis of high-temperature deformation of aluminum and steel. Using physics-based parameters that we expect theoretically to be independent…

Materials Science · Physics 2017-07-19 K. C. Le , T. M. Tran , J. S. Langer

Sensing is one of the most fundamental tasks for the monitoring, forecasting and control of complex, spatio-temporal systems. In many applications, a limited number of sensors are mobile and move with the dynamics, with examples including…

Machine Learning · Computer Science 2023-07-25 Megan R. Ebers , Jan P. Williams , Katherine M. Steele , J. Nathan Kutz

The definition of metastable states is an ubiquitous task in the design and analysis of molecular simulations, and is a crucial input in a variety of acceleration methods for the sampling of long configurational trajectories. Although…

Computational Physics · Physics 2026-04-16 Noé Blassel , Tony Lelièvre , Gabriel Stoltz

This paper tackles the problem of passive gaze estimation using both event and frame data. Considering the inherently different physiological structures, it is intractable to accurately estimate gaze purely based on a given state. Thus, we…

Computer Vision and Pattern Recognition · Computer Science 2024-07-01 Jiading Li , Zhiyu Zhu , Jinhui Hou , Junhui Hou , Jinjian Wu

Understanding transition pathways between two meta-stable states of a molecular system is crucial to advance drug discovery and material design. However, unbiased molecular dynamics (MD) simulations are computationally infeasible because of…

Machine Learning · Computer Science 2025-01-28 Kiyoung Seong , Seonghyun Park , Seonghwan Kim , Woo Youn Kim , Sungsoo Ahn

We describe how we can precisely measure variations in the entropy S of small solid samples below room temperature, as a function the temperature T or the external magnetic field H, respectively. A simple differential-thermal analysis (DTA)…

Instrumentation and Detectors · Physics 2012-12-18 A. Schilling , M. Reibelt

Methods that combine collective variable (CV) based enhanced sampling and global tempering approaches are used in speeding-up the conformational sampling and free energy calculation of large and soft systems with a plethora of energy…

Computational Physics · Physics 2021-09-01 Anji Babu Kapakayala , Nisanth N. Nair

Energy-based models (EBMs) offer a flexible framework for probabilistic modelling across various data domains. However, training EBMs on data in discrete or mixed state spaces poses significant challenges due to the lack of robust and fast…

Machine Learning · Statistics 2024-12-03 Tobias Schröder , Zijing Ou , Yingzhen Li , Andrew B. Duncan