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We propose two different approaches for introducing the information temperature of the binary N-th order Markov chains. The first approach is based on comparing the Markov sequences with the equilibrium Ising chains at given temperatures.…

Data Analysis, Statistics and Probability · Physics 2022-10-05 O. V. Usatenko , S. S. Melnyk , G. M. Pritula , V. A. Yampol'skii

Predictability of behavior has emerged an an important characteristic in many fields including biology, medicine, and marketing. Behavior can be recorded as a sequence of actions performed by an individual over a given time period. This…

Methodology · Statistics 2017-11-13 Brian Vegetabile , Jenny Molet , Tallie Z. Baram , Hal Stern

We investigate on a possible way to connect the presence of Low-Complexity Sequences (LCS) in DNA genomes and the nonstationary properties of base correlations. Under the hypothesis that these variations signal a change in the DNA function,…

A versatile approach to modeling the conformations and energetics of DNA loops is presented. The model is based on the classical theory of elasticity, modified to describe the intrinsic twist and curvature of DNA, the DNA bending…

Biological Physics · Physics 2007-05-23 Alexander Balaeff , L. Mahadevan , Klaus Schulten

The thermodynamic properties of DNA circular molecules are investigated by a new path integral computational method which treats in the real space the fundamental forces stabilizing the molecule. The base pair and stacking contributions to…

Soft Condensed Matter · Physics 2014-11-11 Marco Zoli

Any continuous curve in a higher dimensional space can be considered a trajectory that can be parameterized by a single variable, usually taken as time. It is well known that a continuous curve can have a fractional dimensionality, which…

Data Analysis, Statistics and Probability · Physics 2024-05-08 Roxana Peña-Mendieta , Ania Mesa-Rodríguez , Ernesto Estevez-Rams , Daniel Estevez-Moya , Danays Kunka

Information has an entropic character which can be analyzed within the Statistical Theory in molecular systems. R. Landauer and C.H. Bennett showed that a logical copy can be carried out in the limit of no dissipation if the computation is…

Biological Physics · Physics 2012-08-15 J. Ricardo Arias-Gonzalez

To quantify the randomness of Markov trajectories with fixed initial and final states, Ekroot and Cover proposed a closed-form expression for the entropy of trajectories of an irreducible finite state Markov chain. Numerous applications,…

Information Theory · Computer Science 2016-11-18 Mohamed Kafsi , Matthias Grossglauser , Patrick Thiran

We characterize different cell states, related to cancer and ageing phenotypes, by a measure of entropy of network ensembles, integrating gene expression values and protein interaction networks. The entropy measure estimates the parameter…

Molecular Networks · Quantitative Biology 2013-05-24 G. Menichetti , G. Bianconi , E. Giampieri , G. Castellani , D. Remondini

A theory of symbolic dynamic systems with long-range correlations based on the consideration of the binary N-step Markov chains developed earlier in Phys. Rev. Lett. 90, 110601 (2003) is generalized to the biased case (non equal numbers of…

Data Analysis, Statistics and Probability · Physics 2015-06-26 Z. A. Mayzelis , S. S. Apostolov , S. S. Mel'nyk , O. V. Usatenko , V. A. Yampol'skii

A unified model is constructed to study the recently observed DNA entropic elasticity, cooperative extensibility, and supercoiling property. With the introduction of a new structural parameter (the folding angle $\phi$), bending…

Soft Condensed Matter · Physics 2007-05-23 Zhou Haijun , Zhang Yang , Ou-Yang Zhong-can

Estimating the entropy rate of discrete time series is a challenging problem with important applications in numerous areas including neuroscience, genomics, image processing and natural language processing. A number of approaches have been…

Methodology · Statistics 2023-03-22 Ioannis Papageorgiou , Ioannis Kontoyiannis

Thermalization is one of the most important phenomena in statistical physics. Often, the transition probabilities between different states in the phase space is or can be approximated by constants. In this case, the system can be described…

Statistical Mechanics · Physics 2022-09-13 Francesco Caravelli

Estimating the entropy of a discrete random variable is a fundamental problem in information theory and related fields. This problem has many applications in various domains, including machine learning, statistics and data compression. Over…

Information Theory · Computer Science 2020-12-22 Yuval Shalev , Amichai Painsky , Irad Ben-Gal

The determination of block-entropies is a well established method for the investigation of discrete data, also called symbols (7). There is a large variety of such symbolic sequences, ranging from texts written in natural languages,…

Disordered Systems and Neural Networks · Physics 2007-05-23 Miguel Angel Jimenez-Montano , Werner Ebeling , Thorsten Poeschel

We numerically test the method of non-sequential recursive pair substitutions to estimate the entropy of an ergodic source. We compare its performance with other classical methods to estimate the entropy (empirical frequencies, return…

Statistical Mechanics · Physics 2009-07-21 Lucio M. Calcagnile , Stefano Galatolo , Giulia Menconi

In many biochemical processes, proteins bound to DNA at distant sites are brought into close proximity by loops in the underlying DNA. For example, the function of some gene-regulatory proteins depends on such DNA looping interactions. We…

Quantitative Methods · Quantitative Biology 2009-11-13 John F Beausang , Philip C Nelson

Topological and metric entropies of the DNA sequences from different organisms were calculated. Obtained results were compared each other and with ones of corresponding artificial sequences. For all envisaged DNA sequences there is a…

Statistical Mechanics · Physics 2016-08-31 Olga V. Kirillova

A binary string transmitted via a memoryless i.i.d. deletion channel is received as a subsequence of the original input. From this, one obtains a posterior distribution on the channel input, corresponding to a set of candidate…

Information Theory · Computer Science 2019-03-05 Arash Atashpendar , Marc Beunardeau , Aisling Connolly , Rémi Géraud , David Mestel , A. W. Roscoe , Peter Y. A. Ryan

The Chapter starts with introductory information about quantitative linguistics notions, like rank--frequency dependence, Zipf's law, frequency spectra, etc. Similarities in distributions of words in texts with level occupation in quantum…

Data Analysis, Statistics and Probability · Physics 2024-01-04 Andrij Rovenchak