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Biological tissues are composed of discrete compartments of biochemical media that often exhibit subtle differences in refractive index. Light propagating through these compartments partially diffracts in a forward direction with a pi/2…
Conventional approaches for 3D imaging in or through scattering media are usually limited to 2D reconstruction of objects at some discontinuous locations, although the time-consuming iteration, guide-star, or complex system are implemented.…
Optical imaging relies on the ability to illuminate an object, collect and analyze the light it scatters or transmits. Propagation through complex media such as biological tissues was so far believed to degrade the attainable depth as well…
Purpose: Visualization and monitoring of capillary loops in dermis and mucosa are interesting for various clinical applications, including rheumatology, early cancer, and shock detection. However, the limitations of existing imaging…
Fluorescence microscopic imaging in centimeter-deep tissue has been highly sought-after for many years because much interesting in vivo micro-information, such as microcirculation, tumor angiogenesis, and metastasis, may deeply locate in…
Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…
Imaging with optical resolution through highly scattering media is a long sought-after goal with important applications in deep tissue imaging. Although being the focus of numerous works, this goal was considered impractical until recently.…
We demonstrate the preservation of time-energy entanglement of near-IR photons through thick biological media ($\leq$1.55 mm) and tissue ($\leq$ 235 $\mu$m) at room temperature. Using a Franson-type interferometer, we demonstrate…
Imaging with optical resolution through and inside complex samples is a difficult challenge with important applications in many fields. The fundamental problem is that inhomogeneous samples, such as biological tissues, randomly scatter and…
X-ray "ghost" imaging has drawn great attention for its potential to lower radiation dose in medical diagnosis. For practical implementation, however, the efficiency and image quality have to be greatly improved. Here we demonstrate a…
Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…
Complex-field imaging is indispensable for numerous applications at wavelengths from X-ray to THz, with amplitude describing transmittance (or reflectivity) and phase revealing intrinsic structure of the target object. Coherent diffraction…
We study by means of experiments and Monte Carlo simulations, the scattering of light in random media, to determine the distance upto which photons travel along almost undeviated paths within a scattering medium, and are therefore capable…
X-ray imaging is an invaluable tool for noninvasive analysis in many fields ranging from basic science to medicine and security. The development of low-dose large area imaging solutions still represents an important challenge for various…
Ultrathin lensless fibre endoscopes offer minimally invasive investigation, but they mostly operate as a rigid type due to the need for prior calibration of a fibre probe. Furthermore, most implementations work in fluorescence mode rather…
When waves propagate through a complex medium, they undergo several scattering events. This phenomenon is detrimental to imaging, as it causes full blurring of the image. Here we describe a method for detecting, localizing and…
We present a novel imaging system for ultracold quantum gases in expansion. After release from a confining potential, atoms fall through a sheet of resonant excitation laser light and the emitted fluorescence photons are imaged onto an…
Time-resolved fluorescence imaging is a key tool in biomedical applications, as it allows to non-invasively obtain functional and structural information. However, the big amount of collected data introduces challenges in both acquisition…
Light microscopy as well as image acquisition and processing suffer from physical and technical prejudices which preclude a correct interpretation of biological observations which can be reflected in, e.g., medical and pharmacological…
Low-light-level imaging techniques have application in many diverse fields, ranging from biological sciences to security. We demonstrate a single-photon imaging system based on a time-gated inten- sified CCD (ICCD) camera in which the image…